Complicated grief and related bereavement issues for DSM‐5

Bereavement is a severe stressor that typically incites painful and debilitating symptoms of acute grief that commonly progresses to restoration of a satisfactory, if changed, life. Normally, grief does not need clinical intervention. However, sometimes acute grief can gain a foothold and become a chronic debilitating condition called complicated grief. Moreover, the stress caused by bereavement, like other stressors, can increase the likelihood of onset or worsening of other physical or mental disorders. Hence, some bereaved people need to be diagnosed and treated. A clinician evaluating a bereaved person is at risk for both over‐and under‐diagnosis, either pathologizing a normal condition or neglecting to treat an impairing disorder. The authors of DSM IV focused primarily on the problem of over‐diagnosis, and omitted complicated grief because of insufficient evidence. We revisit bereavement considerations in light of new research findings. This article focuses primarily on a discussion of possible inclusion of a new diagnosis and dimensional assessment of complicated grief. We also discuss modifications in the bereavement V code and refinement of bereavement exclusions in major depression and other disorders. Depression and Anxiety, 2011. © 2011 Wiley‐Liss, Inc.

[1]  G. Prati,et al.  Self-worth mediates the effects of violent loss on PTSD symptoms. , 2011, Journal of traumatic stress.

[2]  Yoshiharu Kim,et al.  Prevalence and determinants of complicated grief in general population. , 2010, Journal of affective disorders.

[3]  R. Bryant,et al.  Social problem solving in complicated grief. , 2010, The British journal of clinical psychology.

[4]  M. Shevlin,et al.  A confirmatory factor analysis of combined models of the Harvard Trauma Questionnaire and the Inventory of Complicated Grief-Revised: are we measuring complicated grief or posttraumatic stress? , 2010, Journal of anxiety disorders.

[5]  H. Chuang,et al.  Determinants of complicated grief in caregivers who cared for terminal cancer patients , 2010, Supportive Care in Cancer.

[6]  H. Prigerson,et al.  Prolonged Grief Disorder, Depression, and Posttraumatic Stress Disorder Among Bereaved Kosovar Civilian War Survivors: a Preliminary Investigation , 2010, The International journal of social psychiatry.

[7]  R. Bryant,et al.  Impaired autobiographical memory in complicated grief. , 2010, Behaviour research and therapy.

[8]  D. Stein,et al.  What is a mental/psychiatric disorder? From DSM-IV to DSM-V , 2010, Psychological Medicine.

[9]  C. Hultman,et al.  The effect of traumatic bereavement on tsunami-exposed survivors. , 2009, Journal of traumatic stress.

[10]  A. Kersting,et al.  Complicated grief in patients with unipolar depression. , 2009, Journal of affective disorders.

[11]  T. Elbert,et al.  Prolonged Grief Disorder and Depression in Widows Due to the Rwandan Genocide , 2009, Omega.

[12]  M. First,et al.  Stigmatization and Receptivity to Mental Health Services Among Recently Bereaved Adults , 2009, Death studies.

[13]  G. Bonanno,et al.  Prolonged Grief Disorder: Psychometric Validation of Criteria Proposed for DSM-V and ICD-11 , 2009, PLoS medicine.

[14]  N. Melhem,et al.  The incidence and course of depression in bereaved youth 21 months after the loss of a parent to suicide, accident, or sudden natural death. , 2009, The American journal of psychiatry.

[15]  S. Zisook,et al.  Grief and bereavement: what psychiatrists need to know , 2009, World psychiatry : official journal of the World Psychiatric Association.

[16]  J. Fontaine,et al.  Confirming the Distinctiveness of Complicated Grief from Depression and Anxiety Among Adolescents , 2009, Death studies.

[17]  E. Uhlenhuth,et al.  Escitalopram: an open-label study of bereavement-related depression and grief. , 2009, Journal of affective disorders.

[18]  H. Prigerson,et al.  Unresolved grief in a national sample of bereaved parents: impaired mental and physical health 4 to 9 years later. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[19]  R. Bryant,et al.  Self-defining memories in complicated grief. , 2008, Behaviour research and therapy.

[20]  S. Zisook,et al.  Does bereavement-related major depression differ from major depression associated with other stressful life events? , 2008, The American journal of psychiatry.

[21]  Joseph M. Currier,et al.  Predictors of grief following the death of one's child: the contribution of finding meaning. , 2008, Journal of clinical psychology.

[22]  Cindy L. Bryce,et al.  Posttraumatic Stress and Complicated Grief in Family Members of Patients in the Intensive Care Unit , 2008, Journal of General Internal Medicine.

[23]  Mary-Frances O'Connor,et al.  Craving love? Enduring grief activates brain's reward center , 2008, NeuroImage.

[24]  H. Prigerson,et al.  Psychiatric illness in the next of kin of patients who die in the intensive care unit* , 2008, Critical care medicine.

[25]  S. Guerin,et al.  A study of complicated grief symptoms in people with intellectual disabilities. , 2008, Journal of intellectual disability research : JIDR.

[26]  R. Morrison,et al.  Elevated Rates of Prolonged Grief Disorder in African Americans , 2008, Death studies.

[27]  A. Kersting,et al.  Association of MAO-A Variant with Complicated Grief in Major Depression , 2008, Neuropsychobiology.

[28]  J. Holland,et al.  Factors of complicated grief pre‐death in caregivers of cancer patients , 2008, Psycho-oncology.

[29]  F. Gutzwiller,et al.  Suicide after bereavement: an overlooked problem , 2008, Psychological Medicine.

[30]  Carol A. Perlman,et al.  Complicated grief and impaired sleep in patients with bipolar disorder. , 2007, Bipolar disorders.

[31]  Tim Dalgleish,et al.  Levels of specificity of autobiographical memories and of biographical memories of the deceased in bereaved individuals with and without complicated grief. , 2007, Journal of abnormal psychology.

[32]  N. Simon,et al.  Complicated grief: a case series using escitalopram. , 2007, The American journal of psychiatry.

[33]  H. Reihani-Kermani,et al.  The prevalence of complicated grief among Bam earthquake survivors in Iran. , 2007, Archives of Iranian medicine.

[34]  Carol A. Perlman,et al.  The prevalence and correlates of psychiatric comorbidity in individuals with complicated grief. , 2007, Comprehensive psychiatry.

[35]  H. Prigerson,et al.  The influence of symptoms of prolonged grief disorder, depression, and anxiety on quality of life among bereaved adults , 2007, European Archives of Psychiatry and Clinical Neuroscience.

[36]  C. Reynolds,et al.  An attachment-based model of complicated grief including the role of avoidance , 2007, European Archives of Psychiatry and Clinical Neuroscience.

[37]  James Savarino,et al.  Suicide attempts among patients starting depression treatment with medications or psychotherapy. , 2007, The American journal of psychiatry.

[38]  S. Maguen,et al.  Prevalence and psychological correlates of complicated grief among bereaved adults 2.5-3.5 years after September 11th attacks. , 2007, Journal of traumatic stress.

[39]  S. Zisook,et al.  Validity of the bereavement exclusion criterion for the diagnosis of major depressive episode. , 2007, World psychiatry : official journal of the World Psychiatric Association.

[40]  G. Bonanno,et al.  Is there more to complicated grief than depression and posttraumatic stress disorder? A test of incremental validity. , 2007, Journal of abnormal psychology.

[41]  C. Reynolds,et al.  Clinical presentation and treatment outcome of African Americans with complicated grief. , 2007, Psychiatric Services.

[42]  W. Nolen,et al.  Cognitive behaviour therapy to prevent complicated grief among relatives and spouses bereaved by suicide: cluster randomised controlled trial , 2007, BMJ : British Medical Journal.

[43]  M. Shear,et al.  Phenomenology and correlates of complicated grief in children and adolescents. , 2007, Journal of the American Academy of Child and Adolescent Psychiatry.

[44]  A. Maercker,et al.  Comparison of two diagnostic systems for Complicated Grief. , 2007, Journal of affective disorders.

[45]  Carol H. Ott,et al.  Spousal Bereavement in Older Adults: Common, Resilient, and Chronic Grief With Defining Characteristics , 2007, The Journal of nervous and mental disease.

[46]  W. Stroebe,et al.  Patterns of Attachment and Parents' Adjustment to the Death of Their Child , 2007, Personality & social psychology bulletin.

[47]  S. Zisook,et al.  Is bereavement-related depression different than non-bereavement-related depression? , 2007, Psychological Medicine.

[48]  D. Sæbye,et al.  Premorbid IQ varies across different definitions of schizophrenia. , 2007, World psychiatry : official journal of the World Psychiatric Association.

[49]  H. Prigerson,et al.  Parental Control, Partner Dependency, and Complicated Grief Among Widowed Adults in the Community , 2007, The Journal of nervous and mental disease.

[50]  P. Boelen,et al.  Negative cognitions and avoidance in emotional problems after bereavement: a prospective study. , 2006, Behaviour research and therapy.

[51]  H. Prigerson,et al.  Update on bereavement research: evidence-based guidelines for the diagnosis and treatment of complicated bereavement. , 2006, Journal of palliative medicine.

[52]  S. Essock,et al.  Screening for complicated grief among Project Liberty service recipients 18 months after September 11, 2001. , 2006, Psychiatric services.

[53]  Song Zhang,et al.  Predictors of complicated grief among dementia caregivers: a prospective study of bereavement. , 2006, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[54]  S. J. Marwit,et al.  An Investigation of the Relationship of Personality, Coping, and Grief Intensity Among Bereaved Mothers , 2006, Death studies.

[55]  Joseph M. Currier,et al.  Sense-Making, Grief, and the Experience of Violent Loss: Toward a Mediational Model , 2006, Death studies.

[56]  E. Frank,et al.  Treating complicated grief and substance use disorders: a pilot study. , 2006, Journal of substance abuse treatment.

[57]  A. Lerner Diagnostic Criteria in Neurology , 2006 .

[58]  Arlen C. Moller,et al.  On the Benefits of Giving as Well as Receiving Autonomy Support: Mutuality in Close Friendships , 2006, Personality & social psychology bulletin.

[59]  Meliss Vessier-Batchen,et al.  Coping and Complicated Grief in Survivors of Homicide and Suicide Decedents , 2006, Journal of forensic nursing.

[60]  C. Reynolds,et al.  Indirect self-destructive behavior and overt suicidality in patients with complicated grief. , 2006, The Journal of clinical psychiatry.

[61]  C. M. Parkes,et al.  An Exploration of Associations Between Separation Anxiety in Childhood and Complicated Grief in Later Life , 2006, The Journal of nervous and mental disease.

[62]  C. M. Parkes Symposium on Complicated Grief , 2006 .

[63]  P. Maciejewski,et al.  A Call for Sound Empirical Testing and Evaluation of Criteria for Complicated Grief Proposed for DSM-V , 2006 .

[64]  H. Schut,et al.  Complicated Grief: A Conceptual Analysis of the Field , 2006 .

[65]  T. Monk,et al.  The Daily Life of Complicated Grief Patients—What Gets Missed, What Gets Added? , 2006, Death studies.

[66]  K. Shear,et al.  Attachment, loss, and complicated grief. , 2005, Developmental psychobiology.

[67]  P. Boelen,et al.  Complicated grief, depression, and anxiety as distinct postloss syndromes: a confirmatory factor analysis study. , 2005, The American journal of psychiatry.

[68]  W. Stroebe,et al.  The broken heart: suicidal ideation in bereavement. , 2005, The American journal of psychiatry.

[69]  J. Lonnqvist,et al.  Suicide prevention strategies: a systematic review. , 2005, JAMA.

[70]  H. Prigerson,et al.  Complicated grief and suicidal ideation in adult survivors of suicide. , 2005, Suicide & life-threatening behavior.

[71]  Carol A. Perlman,et al.  Complicated grief and its correlates in patients with bipolar disorder. , 2005, The Journal of clinical psychiatry.

[72]  Daniel J Buysse,et al.  Sleep quality in complicated grief. , 2005, Journal of traumatic stress.

[73]  C. Reynolds,et al.  Treatment of complicated grief: a randomized controlled trial. , 2005, JAMA.

[74]  R. Glass Is grief a disease? Sometimes. , 2005, JAMA.

[75]  G. Bonanno,et al.  Resilience to loss in bereaved spouses, bereaved parents, and bereaved gay men. , 2005, Journal of personality and social psychology.

[76]  R. Neimeyer,et al.  Insomnia and Complicated Grief Symptoms in Bereaved College Students , 2005, Behavioral sleep medicine.

[77]  R. Langner,et al.  Complicated grief as a stress response disorder: evaluating diagnostic criteria in a German sample. , 2005, Journal of psychosomatic research.

[78]  G. Bonanno,et al.  Grief processing and deliberate grief avoidance: a prospective comparison of bereaved spouses and parents in the United States and the People's Republic of China. , 2005, Journal of consulting and clinical psychology.

[79]  Amy E. Latham,et al.  Suicidality and bereavement: complicated grief as psychiatric disorder presenting greatest risk for suicidality. , 2004, Suicide & life-threatening behavior.

[80]  R. Schulz,et al.  Positive aspects of caregiving and adaptation to bereavement. , 2004, Psychology and aging.

[81]  Z. Steel,et al.  Complicated grief in Bosnian refugees: associations with posttraumatic stress disorder and depression. , 2004, Comprehensive psychiatry.

[82]  C. Reynolds,et al.  Traumatic grief among adolescents exposed to a peer's suicide. , 2004, The American journal of psychiatry.

[83]  G. Bonanno,et al.  Prospective patterns of resilience and maladjustment during widowhood. , 2004, Psychology and aging.

[84]  J. Ogrodniczuk,et al.  Recognizing Complicated Grief in Clinical Practice , 2003, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[85]  P. Boelen,et al.  The role of cognitive variables in psychological functioning after the death of a first degree relative. , 2003, Behaviour research and therapy.

[86]  P. Boelen,et al.  The role of negative interpretations of grief reactions in emotional problems after bereavement. , 2003, Journal of behavior therapy and experimental psychiatry.

[87]  L. Hankoff Reducing Suicide: A National Imperative , 2003 .

[88]  Carol H. Ott THE IMPACT OF COMPLICATED GRIEF ON MENTAL AND PHYSICAL HEALTH AT VARIOUS POINTS IN THE BEREAVEMENT PROCESS , 2003, Death studies.

[89]  J. Ogrodniczuk,et al.  Differentiating Symptoms of Complicated Grief and Depression among Psychiatric Outpatients , 2003, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[90]  P. Boelen,et al.  Positive Thinking in Bereavement: Is it Related to Depression, Anxiety, or Grief Symptomatology? , 2002, Psychological reports.

[91]  N. Laor,et al.  POSTTRAUMATIC, DISSOCIATIVE AND GRIEF SYMPTOMS IN TURKISH CHILDREN EXPOSED TO THE 1999 EARTHQUAKES , 2002, The Journal of nervous and mental disease.

[92]  P. Maciejewski,et al.  RATES AND RISKS OF COMPLICATED GRIEF AMONG PSYCHIATRIC CLINIC PATIENTS IN KARACHI, PAKISTAN , 2002, Death studies.

[93]  C. Reynolds,et al.  Comorbidity of axis I disorders in patients with traumatic grief. , 2001, The Journal of clinical psychiatry.

[94]  K. Meert,et al.  Parental coping and bereavement outcome after the death of a child in the pediatric intensive care unit , 2001, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[95]  J. Ogrodniczuk,et al.  Patient Personality and Time-limited Group Psychotherapy for Complicated Grief , 2001, International journal of group psychotherapy.

[96]  C. Reynolds,et al.  Traumatic grief treatment: a pilot study. , 2001, The American journal of psychiatry.

[97]  S. Zisook,et al.  Bupropion sustained release for bereavement: results of an open trial. , 2001, The Journal of clinical psychiatry.

[98]  Debby E. Doughty,et al.  Traumatic Grief in a Convenience Sample of Victims Seeking Support Services After a Terrorist Incident , 2001, Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists.

[99]  P. Maciejewski,et al.  Quality of life impairments associated with diagnostic criteria for traumatic grief , 2000, Psychological Medicine.

[100]  C. Mazure,et al.  Diagnostic criteria for traumatic grief. , 2000, Death studies.

[101]  D. Kupfer,et al.  Influence of traumatic grief on suicidal ideation among young adults. , 1999, The American journal of psychiatry.

[102]  C. Mazure,et al.  Gender differences in the effects of bereavement-related psychological distress in health outcomes , 1999, Psychological Medicine.

[103]  D. Kupfer,et al.  Treatment of bereavement-related major depressive episodes in later life: a controlled study of acute and continuation treatment with nortriptyline and interpersonal psychotherapy. , 1999, The American journal of psychiatry.

[104]  S. Zisook,et al.  PTSD Following Bereavement , 1998, Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists.

[105]  H. Prigerson,et al.  The influence of marital quality and attachment styles on traumatic grief and depressive symptoms. , 1998, The Journal of nervous and mental disease.

[106]  D. Mazza Bereavement in adult life , 1998, BMJ.

[107]  B. Raphael,et al.  A Longitudinal Study Comparing Bereavement Phenomena in Recently Bereaved Spouses, Adult Children and Parents , 1998, The Australian and New Zealand journal of psychiatry.

[108]  S. Zisook,et al.  The many faces of depression following spousal bereavement. , 1997, Journal of affective disorders.

[109]  M. Hall,et al.  Case Histories of Traumatic Grief , 1997 .

[110]  G. Bonanno,et al.  Diagnostic criteria for complicated grief disorder. , 1997, The American journal of psychiatry.

[111]  C. Reynolds,et al.  Traumatic Grief: A Case of Loss-Induced Trauma , 1997 .

[112]  C. Reynolds,et al.  Suicidal ideation in elderly bereaved: the role of complicated grief. , 1997, Suicide & life-threatening behavior.

[113]  S. Nolen-Hoeksema,et al.  Rumination and psychological distress among bereaved partners. , 1997, Journal of personality and social psychology.

[114]  Daniel J Buysse,et al.  Sleep in the wake of complicated grief symptoms: An exploratory study , 1997, Biological Psychiatry.

[115]  B. Raphael,et al.  Measuring core bereavement phenomena , 1997, Psychological Medicine.

[116]  C. Reynolds,et al.  Complicated grief as a disorder distinct from bereavement-related depression and anxiety: a replication study. , 1996, The American journal of psychiatry.

[117]  M. Hofer On the Nature and Consequences of Early Loss , 1996, Psychosomatic medicine.

[118]  C. Reynolds,et al.  Inventory of complicated grief: A scale to measure maladaptive symptoms of loss , 1995, Psychiatry Research.

[119]  R A McCormick,et al.  Testing a tripartite model: II. Exploring the symptom structure of anxiety and depression in student, adult, and patient samples. , 1995, Journal of abnormal psychology.

[120]  R A McCormick,et al.  Testing a tripartite model: I. Evaluating the convergent and discriminant validity of anxiety and depression symptom scales. , 1995, Journal of abnormal psychology.

[121]  D. Brent,et al.  Major depression or uncomplicated bereavement? A follow-up of youth exposed to suicide. , 1994, Journal of the American Academy of Child and Adolescent Psychiatry.

[122]  M. Horowitz,et al.  Pathological grief: an intensive case study. , 1993, Psychiatry.

[123]  G. Bonanno,et al.  Pathological grief: diagnosis and explanation. , 1993, Psychosomatic medicine.

[124]  S. Zisook,et al.  Early psychological reaction to the stress of widowhood. , 1991, Psychiatry.

[125]  D. Watson,et al.  Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications. , 1991, Journal of abnormal psychology.

[126]  Daniel J Buysse,et al.  Acute open-trial nortriptyline therapy of bereavement-related depression in late life. , 1991, The Journal of clinical psychiatry.

[127]  S. J. Marwit DSM-III-R, grief reactions, and a call for revision , 1991 .

[128]  S. Zisook,et al.  Factors in the persistence of unresolved grief among psychiatric outpatients. , 1985, Psychosomatics.

[129]  M. Hofer,et al.  Relationships as regulators: a psychobiologic perspective on bereavement. , 1984, Psychosomatic medicine.

[130]  C. Marmar,et al.  Pathological grief and the activation of latent self-images. , 1980, The American journal of psychiatry.

[131]  John Bowlby,et al.  Loss--Sadness and Depression , 1980 .

[132]  S. Zisook,et al.  Clinical aspects of grief and bereavement. , 1979, Primary care.

[133]  S. Zisook,et al.  Psychiatry: unresolved grief. Clinical considerations. , 1976, Postgraduate medicine.

[134]  C. M. Parkes The First Year of Bereavement †. , 1974, Psychiatry.

[135]  C. M. Parkes BEREAVEMENT AND MENTAL ILLNESS. 1. A CLINICAL STUDY OF THE GRIEF OF BEREAVED PSYCHIATRIC PATIENTS. , 1965, The British journal of medical psychology.

[136]  C. M. Parkes Effects of Bereavement on Physical and Mental Health—a Study of the Medical Records of Widows , 1964, British medical journal.

[137]  Parkes Cm Effects of Bereavement on Physical and Mental Health—a Study of the Medical Records of Widows , 1964 .

[138]  G. L. Engel Is Grief a Disease?: A Challenge for Medical Research , 1961, Psychosomatic medicine.

[139]  Sigmund Freud,et al.  Mourning and Melancholia , 1922 .

[140]  M. Nagamine,et al.  [Mental health of the families of crime victims and factors related to their recovery]. , 2009, Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.

[141]  P. Buckley Antecedents and Sequelae of Sudden Parental Death in Offspring and Surviving Caregivers , 2009 .

[142]  S. Murphy The loss of a child: Sudden death and extended illness perspectives. , 2008 .

[143]  W. Stroebe,et al.  Ruminative coping as avoidance: a reinterpretation of its function in adjustment to bereavement. , 2007, European archives of psychiatry and clinical neuroscience.

[144]  A. Kersting,et al.  Complicated grief after traumatic loss: a 14-month follow up study. , 2007, European archives of psychiatry and clinical neuroscience.

[145]  H. Prigerson,et al.  Complicated grief in survivors of suicide. , 2004, Crisis.

[146]  D. R. Lehman,et al.  Resilience to loss and chronic grief: a prospective study from preloss to 18-months postloss. , 2002, Journal of personality and social psychology.

[147]  M K Shear,et al.  Traumatic grief as a risk factor for mental and physical morbidity. , 1997, The American journal of psychiatry.

[148]  D. Kupfer,et al.  Anxiety among widowed elders: is it distinct from depression and grief? , 1996, Anxiety.

[149]  M. Viederman Grief: normal and pathological variants. , 1995, The American journal of psychiatry.

[150]  D. Kupfer,et al.  Complicated grief and bereavement-related depression as distinct disorders: preliminary empirical validation in elderly bereaved spouses. , 1995, The American journal of psychiatry.

[151]  S. Zisook,et al.  Anxiety and bereavement. , 1990, Psychiatric medicine.

[152]  G. Hartz Adult grief and its interface with mood disorder: proposal of a new diagnosis of complicated bereavement. , 1986, Comprehensive psychiatry.

[153]  C. Dopson,et al.  Unresolved grief in the family. , 1983, American family physician.

[154]  Harper Mb,et al.  Unresolved grief in the family. , 1983 .

[155]  C. M. Parkes Bereavement; studies of grief in adult life , 1972 .

[156]  C. M. Parkes The first year of bereavement. A longitudinal study of the reaction of London widows to the death of their husbands. , 1970, Psychiatry.

[157]  G. L. Engel,et al.  GRIEF AND GRIEVING. , 1964, The American journal of nursing.

[158]  S. Freud The Standard Edition of the Complete Psychological Works of Sigmund Freud , 1953 .