Emerging Role of SIGIRR rs7396562(T/G) Polymorphism in Systemic Lupus Erythematosus in a Chinese Population

[1]  D. Ye,et al.  Therapeutic potential of SIGIRR in systemic lupus erythematosus , 2013, Rheumatology International.

[2]  C. Kimchi-Sarfaty,et al.  Understanding the contribution of synonymous mutations to human disease , 2011, Nature Reviews Genetics.

[3]  C. Garlanda,et al.  SIGIRR/TIR-8 is an inhibitor of Toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis. , 2010, Arthritis and rheumatism.

[4]  C. Garlanda,et al.  Lack of SIGIRR/TIR8 aggravates hydrocarbon oil‐induced lupus nephritis , 2010, The Journal of pathology.

[5]  S. Akira,et al.  Pattern Recognition Receptors and Inflammation , 2010, Cell.

[6]  C. Dinarello,et al.  High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein. , 2010, Journal of autoimmunity.

[7]  V. Tuohy,et al.  The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. , 2010, Immunity.

[8]  L. Rönnblom,et al.  C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis. , 2009, Arthritis and rheumatism.

[9]  C. Garlanda,et al.  TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. , 2009, Trends in immunology.

[10]  D. Pisetsky,et al.  The Role of Extracellular DNA in Autoimmunity in SLE , 2009, Scandinavian journal of immunology.

[11]  J. Lünemann,et al.  Antiviral immune responses: triggers of or triggered by autoimmunity? , 2009, Nature Reviews Immunology.

[12]  Xia Li,et al.  The Essential Role of Single Ig IL-1 Receptor-Related Molecule/Toll IL-1R8 in Regulation of Th2 Immune Response1 , 2009, The Journal of Immunology.

[13]  C. Garlanda,et al.  Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens , 2008, The Journal of experimental medicine.

[14]  K. Chow,et al.  Climatic influence on the prevalence of noncutaneous disease flare in systemic lupus erythematosus in Hong Kong. , 2008, The Journal of rheumatology.

[15]  C. Garlanda,et al.  Damping Excessive Inflammation and Tissue Damage in Mycobacterium tuberculosis Infection by Toll IL-1 Receptor 8/Single Ig IL-1-Related Receptor, a Negative Regulator of IL-1/TLR Signaling1 , 2007, The Journal of Immunology.

[16]  A. Mansell,et al.  The negative regulation of Toll‐like receptor and associated pathways , 2007, Immunology and cell biology.

[17]  M. Feldmann,et al.  Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP. , 2004, Blood.

[18]  C. Garlanda,et al.  Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[19]  L. O’Neill SIGIRR puts the brakes on Toll-like receptors , 2003, Nature Immunology.

[20]  G. Hughes,et al.  Morbidity and Mortality in Systemic Lupus Erythematosus During a 10-Year Period: A Comparison of Early and Late Manifestations in a Cohort of 1,000 Patients , 2003, Medicine.

[21]  G. Stark,et al.  SIGIRR, a negative regulator of Toll-like receptor–interleukin 1 receptor signaling , 2003, Nature Immunology.

[22]  T. McAlindon Update on the epidemiology of systemic lupus erythematosus: new spins on old ideas , 2000, Current opinion in rheumatology.

[23]  J. Sims,et al.  Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily. , 1999, Cytokine.

[24]  M. Hochberg,et al.  Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. , 1997, Arthritis and rheumatism.

[25]  P. Gregersen,et al.  Microarray Analyses of Peripheral Blood Cells Identifies Unique Gene Expression Signature in Psoriatic Arthritis , 2005, Molecular medicine.