Intraoperative Plasma: Rbc Ratio Affects Postoperative Coagulopathy And Resuscitation Requirements

Early and increased amounts of plasma have been associated with improved survival after penetrating and blunt injury. However, no studies involving burn patients demonstrate the effects of intraoperative plasma administration on postoperative resuscitation requirements. This study examined perioperative transfusion ratios [plasma:RBC (P:R)] and the role of early, aggressive plasma administration in a contemporary burn center.

[1]  Martin H. Dauber,et al.  Miller’s Anesthesia , 2010 .

[2]  D. Dries.  The Ratio of Blood Products Transfused Affects Mortality in Patients Receiving Massive Transfusions at a Combat Support Hospital , 2009 .

[3]  J. Michalek,et al.  Increased Plasma and Platelet to Red Blood Cell Ratios Improves Outcome in 466 Massively Transfused Civilian Trauma Patients , 2008, Annals of surgery.

[4]  A. Sauaia,et al.  Postinjury life threatening coagulopathy: is 1:1 fresh frozen plasma:packed red blood cells the answer? , 2008, The Journal of trauma.

[5]  J. Duchesne,et al.  Review of current blood transfusions strategies in a mature level I trauma center: were we wrong for the last 60 years? , 2008, The Journal of trauma.

[6]  J. Holcomb,et al.  Transfusion practice in military trauma , 2008, Transfusion medicine.

[7]  C. Wade,et al.  Effect of plasma and red blood cell transfusions on survival in patients with combat related traumatic injuries. , 2008, The Journal of trauma.

[8]  J. Hunt,et al.  The Parkland Formula Under Fire: Is the Criticism Justified? , 2008, Journal of burn care & research : official publication of the American Burn Association.

[9]  C. Wade,et al.  The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. , 2007, The Journal of trauma.

[10]  C. Cocanour,et al.  Fresh frozen plasma should be given earlier to patients requiring massive transfusion. , 2007, The Journal of trauma.

[11]  Andrew D. Rosenberg,et al.  Practice guidelines for perioperative blood transfusion and adjuvant therapies: An updated report by the American Society of Anesthesiologists Task Force on perioperative blood transfusion and adjuvant therapies , 2006 .

[12]  Jeffrey L. Apfelbaum,et al.  Practice Guidelines for Perioperative Blood Transfusion and Adjuvant Therapies: An Updated Report by the American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies , 2006, Anesthesiology.

[13]  E. Moore,et al.  Evolution of a Multidisciplinary Clinical Pathway for the Management of Unstable Patients With Pelvic Fractures , 2001, Annals of surgery.

[14]  Consensus conference. Fresh-frozen plasma. Indications and risks. , 1985, JAMA.