Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity.
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Antonio Lopez-Beltran | Alexander Kutikov | Andrew J Armstrong | B. Shuch | A. Lopez‐Beltran | A. Armstrong | B. Rini | J. Eble | G. Martignoni | V. Ficarra | A. Amin | A. Kutikov | John N Eble | Guido Martignoni | Vincenzo Ficarra | Brian I Rini | Brian Shuch | Ali Amin | A. López-Beltran
[1] J. Reeves,et al. Pazopanib versus sunitinib in metastatic renal-cell carcinoma. , 2013, The New England journal of medicine.
[2] M. Ladanyi,et al. Distinctive neoplasms characterised by specific chromosomal translocations comprise a significant proportion of paediatric renal cell carcinomas. , 2003, Pathology.
[3] M. Ladanyi,et al. Xp11 Translocation Renal Cell Carcinoma in Adults: Expanded Clinical, Pathologic, and Genetic Spectrum , 2007, The American journal of surgical pathology.
[4] K. Dykema,et al. Combining differential expression, chromosomal and pathway analyses for the molecular characterization of renal cell carcinoma. , 2012, Canadian Urological Association journal = Journal de l'Association des urologues du Canada.
[5] Holger Moch,et al. Morphologic and Molecular Characterization of Renal Cell Carcinoma in Children and Young Adults , 2004, The American journal of surgical pathology.
[6] S. Boorjian,et al. The impact of temporal presentation on clinical and pathological outcomes for patients with sporadic bilateral renal masses. , 2008, European urology.
[7] G. Kovacs,et al. Differentiation between papillary and nonpapillary renal cell carcinomas by DNA analysis. , 1989, Journal of the National Cancer Institute.
[8] R. Motzer,et al. Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma , 2012, Cancer.
[9] E. Plimack,et al. Coexisting hybrid malignancy in a solitary sporadic solid benign renal mass: implications for treating patients following renal biopsy. , 2014, The Journal of urology.
[10] P. Camparo,et al. Hybrid oncocytic/chromophobe renal cell tumours do not display genomic features of chromophobe renal cell carcinomas , 2013, Virchows Archiv.
[11] Ximing J. Yang,et al. Detection of DNA copy number changes and oncogenic signaling abnormalities from gene expression data reveals MYC activation in high-grade papillary renal cell carcinoma. , 2007, Cancer research.
[12] Steven J. M. Jones,et al. Comprehensive molecular characterization of clear cell renal cell carcinoma , 2013, Nature.
[13] S. Fleming,et al. Collecting duct carcinoma of the kidney , 1986, Histopathology.
[14] Lars Egevad,et al. The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia , 2013, The American journal of surgical pathology.
[15] Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas , 1997, Nature Genetics.
[16] J. Cheville,et al. Solid renal tumors: an analysis of pathological features related to tumor size. , 2003, The Journal of urology.
[17] P. Russo,et al. Chromophobe Renal Cell Carcinoma: A Clinicopathologic Study of 203 Tumors in 200 Patients With Primary Resection at a Single Institution , 2011, The American journal of surgical pathology.
[18] C. Stief,et al. Impact of clinical and histopathological parameters on disease specific survival in patients with collecting duct renal cell carcinoma: development of a disease specific risk model. , 2013, The Journal of urology.
[19] R. Motzer,et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial , 2011, The Lancet.
[20] G. Alves,et al. Pathology and Genetics , 2014 .
[21] A. Belldegrun,et al. Quality of pathological reporting for renal cell cancer: implications for systemic therapy, prognostication and surveillance , 2011, BJU international.
[22] R. Parker,et al. Histologic Predictors of Renal Cell Carcinoma Response to Interleukin-2-Based Therapy , 2005, Journal of immunotherapy.
[23] J. Cheville,et al. Histological subtype is an independent predictor of outcome for patients with renal cell carcinoma. , 2010, The Journal of urology.
[24] B. Rini,et al. Erratum: Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial (Lancet (2011) 378 (1931-39)) , 2012 .
[25] M. Ladanyi,et al. Utilization of a TFE3 Break-apart FISH Assay in a Renal Tumor Consultation Service , 2013, The American journal of surgical pathology.
[26] J. Cheville,et al. Comparisons of Outcome and Prognostic Features Among Histologic Subtypes of Renal Cell Carcinoma , 2003, The American journal of surgical pathology.
[27] P. Camparo,et al. Targeted agents in metastatic Xp11 translocation/TFE3 gene fusion renal cell carcinoma (RCC): a report from the Juvenile RCC Network. , 2009, Annals of oncology : official journal of the European Society for Medical Oncology.
[28] Z. Gatalica,et al. Sporadic hybrid oncocytic/chromophobe tumor of the kidney: a clinicopathologic, histomorphologic, immunohistochemical, ultrastructural, and molecular cytogenetic study of 14 cases , 2010, Virchows Archiv.
[29] A. Zisman,et al. Renal oncocytoma--are there sufficient grounds to consider surveillance following prenephrectomy histologic diagnosis. , 2012, Urologic oncology.
[30] T. Choueiri,et al. Metastatic non–clear cell renal cell carcinoma treated with targeted therapy agents: Characterization of survival outcome and application of the International mRCC Database Consortium criteria , 2013, Cancer.
[31] J. Ioannidis,et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. , 2009, Annals of Internal Medicine.
[32] Arianna Di Napoli,et al. Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney. , 2009, Cancer research.
[33] M. Merino,et al. The Morphologic Spectrum of Kidney Tumors in Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC) Syndrome , 2007, The American journal of surgical pathology.
[34] G. Demetri,et al. Tivantinib (ARQ 197), a selective inhibitor of MET, in patients with microphthalmia transcription factor–associated tumors , 2012, Cancer.
[35] J. Manola,et al. A phase II trial of doxorubicin and gemcitabine in renal cell carcinoma with sarcomatoid features: ECOG 8802 , 2012, Medical Oncology.
[36] S. Culine,et al. Prospective multicenter phase II study of gemcitabine plus platinum salt for metastatic collecting duct carcinoma: results of a GETUG (Groupe d'Etudes des Tumeurs Uro-Génitales) study. , 2007, The Journal of urology.
[37] Michael J Wallace,et al. Percutaneous biopsy of primary tumor in metastatic renal cell carcinoma to predict high risk pathological features: comparison with nephrectomy assessment. , 2010, The Journal of urology.
[38] R. Ghavamian,et al. Renal medullary carcinoma: the Bronx experience. , 2007, Urology.
[39] Bohuslav Melichar,et al. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial , 2007, The Lancet.
[40] R. Uzzo,et al. Pathological concordance and surgical outcomes of sporadic synchronous unilateral multifocal renal masses treated with partial nephrectomy. , 2013, The Journal of urology.
[41] C. Sternberg,et al. Pazopanib in Locally Advanced or Metastatic Renal Cell Carcinoma: Results of a Randomized Phase III Trial , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[42] A. Scarpa,et al. Pathology and Genetics , 2010 .
[43] W Marston Linehan,et al. The genetic basis of cancer of kidney cancer: implications for gene‐specific clinical management , 2005, BJU international.
[44] W. Samlowski,et al. Phase II study of erlotinib in patients with locally advanced or metastatic papillary histology renal cell cancer: SWOG S0317. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[45] M. Milowsky,et al. Active chemotherapy for sarcomatoid and rapidly progressing renal cell carcinoma , 2004, Cancer.
[46] R. Figlin,et al. Prolonged survival with personalized immunotherapy (AGS-003) in combination with sunitinib in unfavorable risk metastatic RCC (mRCC). , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[47] Mahul B. Amin,et al. Prognostic Impact of Histologic Subtyping of Adult Renal Epithelial Neoplasms: An Experience of 405 Cases , 2002, The American journal of surgical pathology.
[48] A. G. Kessel,et al. Nuclear localization and transactivating capacities of the papillary renal cell carcinoma-associated TFE3 and PRCC (fusion) proteins , 2000, Oncogene.
[49] R. Motzer,et al. Medullary renal cell carcinoma and response to therapy with bortezomib. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[50] M. Merino,et al. Collecting duct carcinoma of the kidney. , 1990, Human pathology.
[51] M. Atkins,et al. Phase II trial of carboplatin and paclitaxel in papillary renal cell carcinoma. , 2009, Clinical genitourinary cancer.
[52] L. Ngo,et al. Angiomyolipoma with minimal fat: can it be differentiated from clear cell renal cell carcinoma by using standard MR techniques? , 2012, Radiology.
[53] Maria Merino,et al. Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome. , 2002, Cancer cell.
[54] M. Colecchia,et al. Treatment of collecting duct carcinoma: current status and future perspectives. , 2014, Anticancer research.
[55] R. Grobholz,et al. Collecting Duct Carcinomas Represent a Unique Tumor Entity Based on Genetic Alterations , 2013, PloS one.
[56] B. Delahunt,et al. Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families. , 2002, Cancer research.
[57] R. Motzer,et al. Treatment outcome with mTOR inhibitors for metastatic renal cell carcinoma with nonclear and sarcomatoid histologies. , 2014, Annals of oncology : official journal of the European Society for Medical Oncology.
[58] N. Vogelzang,et al. Disease-Specific Survival in De Novo Metastatic Renal Cell Carcinoma in the Cytokine and Targeted Therapy Era , 2013, PloS one.
[60] P. Argani,et al. Dysregulation of the mammalian target of rapamycin pathway in chromophobe renal cell carcinomas. , 2013, Human pathology.
[61] W. Linehan,et al. Renal Tumors in the Birt-Hogg-Dubé Syndrome , 2002, The American journal of surgical pathology.
[62] L. Schwartz,et al. Sarcomatoid-variant Renal Cell Carcinoma: Treatment Outcome and Survival in Advanced Disease , 2011, American journal of clinical oncology.
[63] M. Gordon,et al. Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma , 2008 .
[64] Apurva A Desai,et al. Sorafenib in advanced clear-cell renal-cell carcinoma. , 2007, The New England journal of medicine.
[65] R. Motzer,et al. Treatment outcome and survival associated with metastatic renal cell carcinoma of non-clear-cell histology. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[66] C. Lohse,et al. Multifocal Renal Cell Carcinoma: Clinicopathologic Features and Outcomes for Tumors ≤4 cm , 2008, Advances in urology.
[67] Steven J. M. Jones,et al. Comprehensive molecular characterization of clear cell renal cell carcinoma , 2013, Nature.
[68] Amnon Zisman,et al. Cytogenetic and Molecular Tumor Profiling for Type 1 and Type 2 Papillary Renal Cell Carcinoma , 2009, Clinical Cancer Research.
[69] B. Delahunt,et al. Uncommon and recently described renal carcinomas , 2009, Modern Pathology.
[70] J. Sosman,et al. A study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors. , 2013 .
[71] P. Choyke,et al. Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancer. , 2007, The Journal of urology.
[72] David C. Smith,et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. , 2012, The New England journal of medicine.
[73] M. Remzi,et al. Comparison of type I and II papillary renal cell carcinoma (RCC) and clear cell RCC , 2008, BJU international.
[74] W. Linehan,et al. Targeting the mTOR pathway in Chromophobe Kidney Cancer , 2012, Journal of Cancer.
[75] B. Delahunt,et al. Morphologic typing of papillary renal cell carcinoma: comparison of growth kinetics and patient survival in 66 cases. , 2001, Human pathology.
[76] W. Marston Linehan,et al. Molecular Sub-Classification of Renal Epithelial Tumors Using Meta-Analysis of Gene Expression Microarrays , 2011, PloS one.
[77] P. Russo,et al. Immunohistochemical expression of hypoxia inducible factor-1alpha and its downstream molecules in sarcomatoid renal cell carcinoma. , 2007, Journal of Urology.
[78] L. Truong,et al. Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms , 2005, Modern Pathology.
[79] A. Paetau,et al. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer , 2002, Nature Genetics.
[80] P. Argani,et al. Translocation renal cell carcinoma , 2008, Cancer.
[81] G. Kovacs,et al. Molecular cytogenetics of renal cell tumors. , 1993, Advances in cancer research.
[82] W. Rathmell,et al. High-dose-intensity MVAC for Advanced Renal Medullary Carcinoma: Report of Three Cases and Literature Review. , 2008, Urology.
[83] A. Nagy,et al. Lack of mutation of the folliculin gene in sporadic chromophobe renal cell carcinoma and renal oncocytoma , 2004, International journal of cancer.
[84] Lisa L. Smith,et al. A phase 2 trial of sunitinib in patients with advanced non-clear cell renal cell carcinoma. , 2012, European urology.
[85] F. Mostofi,et al. Renal Medullary Carcinoma The Seventh Sickle Cell Nephropathy , 1995, The American journal of surgical pathology.
[86] J. Brooks,et al. Mutations of the VHL tumour suppressor gene in renal carcinoma , 1994, Nature Genetics.
[87] R. Motzer,et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial , 2008, The Lancet.
[88] A. Belldegrun,et al. Cytoreductive nephrectomy for kidney cancer with sarcomatoid histology--is up-front resection indicated and, if not, is it avoidable? , 2009, The Journal of urology.
[89] M. Gordon. Metastatic Sarcomatoid Renal Cell Carcinoma Treated With Vascular Endothelial Growth Factor–Targeted Therapy , 2009 .
[90] A. Belldegrun,et al. Pathobiology and prognosis of chromophobe renal cell carcinoma. , 2008, Urologic oncology.
[91] M. Zhou,et al. Renal mass biopsy--a renaissance? , 2008, The Journal of urology.
[92] Ximing J. Yang,et al. Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma , 2010, BMC Cancer.
[93] K. Moon,et al. Sarcomatoid differentiation as a prognostic factor for immunotherapy in metastatic renal cell carcinoma , 2007, Journal of surgical oncology.
[94] P. Tamboli,et al. Vascular endothelial growth factor‐targeted therapy for the treatment of adult metastatic Xp11.2 translocation renal cell carcinoma , 2010, Cancer.
[95] J. Srigley,et al. Collecting duct carcinoma of kidney. , 1998, Seminars in diagnostic pathology.
[96] B. Trock,et al. Multiphasic enhancement patterns of small renal masses (≤4 cm) on preoperative computed tomography: utility for distinguishing subtypes of renal cell carcinoma, angiomyolipoma, and oncocytoma. , 2012, Urology.
[97] M. Ladanyi,et al. TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition. , 2007, Cancer research.
[98] S. Störkel,et al. Ultrastructural appearance and cytoskeletal architecture of the clear, chromophilic, and chromophobe types of human renal cell carcinoma in vitro. , 1993, The American journal of pathology.
[99] J. Ioannidis,et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. , 2009, Journal of clinical epidemiology.
[100] S. Störkel,et al. Human chromophobe cell renal carcinoma , 1985, Virchows Archiv. B, Cell pathology including molecular pathology.
[101] E. Jellinek. Grawitz Tumor of Kidney. , 1904, California state journal of medicine.
[102] R. Figlin,et al. Collecting duct renal cell carcinoma: clinical study of a rare tumor. , 2002, The Journal of urology.
[103] A. Belldegrun,et al. Impact of pathological tumour characteristics in patients with sarcomatoid renal cell carcinoma , 2012, BJU international.
[104] N. Rioux-Leclercq,et al. Prognostic value of histologic subtypes in renal cell carcinoma: a multicenter experience. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[105] M. Ladanyi,et al. Translocation carcinomas of the kidney after chemotherapy in childhood. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[106] E. Perlman,et al. Renal medullary carcinoma: clinical, pathologic, immunohistochemical, and genetic analysis with pathogenetic implications. , 2002, Urology.
[107] Y. Allory,et al. Triple combination of bevacizumab, gemcitabine and platinum salt in metastatic collecting duct carcinoma. , 2013, Annals of oncology : official journal of the European Society for Medical Oncology.
[108] W. Linehan,et al. Sarcomatoid renal cell carcinoma: a comprehensive review of the biology and current treatment strategies. , 2012, The oncologist.
[109] M. Ali,et al. Sarcomatoid renal cell carcinoma: the chromophobe connection. , 1997, The American journal of surgical pathology.
[110] David McDermott,et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. , 2007, The New England journal of medicine.
[111] F. Waldman,et al. Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors , 2008, Clinical Cancer Research.
[112] L. Truong,et al. Clear cell papillary renal cell carcinoma is the fourth most common histologic type of renal cell carcinoma in 290 consecutive nephrectomies for renal cell carcinoma. , 2014, Human pathology.
[113] R. Motzer,et al. Treatment outcome for metastatic papillary renal cell carcinoma patients , 2006, Cancer.
[114] Keith T Flaherty,et al. Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[115] D. Grignon,et al. Clear cell papillary renal cell carcinoma: differential diagnosis and extended immunohistochemical profile , 2013, Modern Pathology.
[116] Ximing J. Yang,et al. Gene expression profiling of renal medullary carcinoma , 2004, Cancer.