Mutational heterogeneity in human cancers: origin and consequences.
暂无分享,去创建一个
[1] Sven Diederichs,et al. The hallmarks of cancer , 2012, RNA biology.
[2] R. Beckman. Mutator Mutations Enhance Tumorigenic Efficiency across Fitness Landscapes , 2009, PloS one.
[3] D. Louis,et al. Faculty Opinions recommendation of Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. , 2009 .
[4] Kun-Liang Guan,et al. Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α , 2009, Science.
[5] J. Stamatoyannopoulos,et al. Human mutation rate associated with DNA replication timing , 2009, Nature Genetics.
[6] M. Bronner,et al. Genomic biomarkers to improve ulcerative colitis neoplasia surveillance. , 2008, The American journal of pathology.
[7] P. Hanawalt,et al. Transcription-coupled DNA repair: two decades of progress and surprises , 2008, Nature Reviews Molecular Cell Biology.
[8] Andrey Korshunov,et al. Analysis of the IDH1 codon 132 mutation in brain tumors , 2008, Acta Neuropathologica.
[9] G. Parmigiani,et al. Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers , 2008, Proceedings of the National Academy of Sciences.
[10] Amy E. Hawkins,et al. DNA sequencing of a cytogenetically normal acute myeloid leukemia genome , 2008, Nature.
[11] Brian H. Dunford-Shore,et al. Somatic mutations affect key pathways in lung adenocarcinoma , 2008, Nature.
[12] G. Parmigiani,et al. Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses , 2008, Science.
[13] D. Busam,et al. An Integrated Genomic Analysis of Human Glioblastoma Multiforme , 2008, Science.
[14] Joshua M. Korn,et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways , 2008, Nature.
[15] M. Stratton,et al. Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing , 2008, Proceedings of the National Academy of Sciences.
[16] C. Harris,et al. Advances in chemical carcinogenesis: a historical review and prospective. , 2008, Cancer research.
[17] L. Loeb,et al. DNA polymerases and human disease , 2008, Nature Reviews Genetics.
[18] N. Wright,et al. Colonic crypt organization and tumorigenesis , 2008, Nature Reviews Cancer.
[19] Antony V. Cox,et al. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing , 2008, Nature Genetics.
[20] Robert A Beckman,et al. Genetic instability is not a requirement for tumor development. , 2008, Cancer research.
[21] Robert A Beckman,et al. Cancers exhibit a mutator phenotype: clinical implications. , 2008, Cancer research.
[22] A. Ullrich,et al. Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer. , 2008, Cancer cell.
[23] Rakesh Nagarajan,et al. Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. , 2008, Blood.
[24] Martin A. Nowak,et al. Comparative lesion sequencing provides insights into tumor evolution , 2008, Proceedings of the National Academy of Sciences.
[25] Sam W. Lee,et al. Clonal selection in malignant transformation of human fibroblasts transduced with defined cellular oncogenes. , 2008, Cancer research.
[26] K. Kinzler,et al. Epitope landscape in breast and colorectal cancer. , 2008, Cancer research.
[27] Derek Y. Chiang,et al. Characterizing the cancer genome in lung adenocarcinoma , 2007, Nature.
[28] S. Fröhling,et al. High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia. , 2007, Blood.
[29] A. Sparks,et al. The Genomic Landscapes of Human Breast and Colorectal Cancers , 2007, Science.
[30] Carlo C. Maley,et al. Animal Cell Differentiation Patterns Suppress Somatic Evolution , 2007, PLoS Comput. Biol..
[31] Giovanni Parmigiani,et al. Response to Comments on "The Consensus Coding Sequences of Human Breast and Colorectal Cancers" , 2007, Science.
[32] Guy Cavet,et al. Comment on "The Consensus Coding Sequences of Human Breast and Colorectal Cancers" , 2007, Science.
[33] Shenghui He,et al. Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU , 2007, Nature.
[34] Martin A. Nowak,et al. Genetic Progression and the Waiting Time to Cancer , 2007, PLoS Comput. Biol..
[35] D. Lin,et al. Fen1 mutations result in autoimmunity, chronic inflammation and cancers , 2007, Nature Medicine.
[36] S. Nakajima,et al. Werner syndrome protein interacts functionally with translesion DNA polymerases , 2007, Proceedings of the National Academy of Sciences.
[37] C. Maley,et al. Increasing genomic instability during premalignant neoplastic progression revealed through high resolution array‐CGH , 2007, Genes, chromosomes & cancer.
[38] G. Prindull,et al. Are postnatal hemangioblasts generated by dedifferentiation from committed hematopoietic stem cells? , 2007, Experimental hematology.
[39] E. Birney,et al. Patterns of somatic mutation in human cancer genomes , 2007, Nature.
[40] W. Gerald,et al. A Genome-Wide Screen for Promoter Methylation in Lung Cancer Identifies Novel Methylation Markers for Multiple Malignancies , 2006, PLoS medicine.
[41] C. Maley,et al. Cancer as an evolutionary and ecological process , 2006, Nature Reviews Cancer.
[42] Lawrence D True,et al. Human cancers express a mutator phenotype , 2006, Proceedings of the National Academy of Sciences.
[43] J. Cairns,et al. Anecdotal, Historical and Critical Commentaries on Genetics : Paradox Found , 1987 .
[44] L. Loeb,et al. Efficiency of carcinogenesis with and without a mutator mutation , 2006, Proceedings of the National Academy of Sciences.
[45] P. Hanawalt,et al. DNA repair: from molecular mechanism to human disease. , 2006, DNA repair.
[46] Susan O'Brien,et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. , 2006, The New England journal of medicine.
[47] S. Nishimura. 8-Hydroxyguanine: From its discovery in 1983 to the present status , 2006, Proceedings of the Japan Academy. Series B, Physical and biological sciences.
[48] Hongyue Dai,et al. Gene expression changes associated with progression and response in chronic myeloid leukemia. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[49] Richard Lugg,et al. Sequence analysis of the protein kinase gene family in human testicular germ‐cell tumors of adolescents and adults , 2006, Genes, chromosomes & cancer.
[50] L. Loeb,et al. Negative Clonal Selection in Tumor Evolution , 2005, Genetics.
[51] Andrew D. Yates,et al. Somatic mutations of the protein kinase gene family in human lung cancer. , 2005, Cancer research.
[52] Martin A. Nowak,et al. Dynamics of chronic myeloid leukaemia , 2005, Nature.
[53] Andrew D. Yates,et al. A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer , 2005, Nature Genetics.
[54] J. Bielas,et al. Quantification of random genomic mutations , 2005, Nature Methods.
[55] R. Weinberg,et al. Species- and cell type-specific requirements for cellular transformation. , 2004, Cancer cell.
[56] B. Druker. Imatinib: Paradigm or Anomaly? , 2004, Cell cycle.
[57] Giovanni Parmigiani,et al. Mutational Analysis of the Tyrosine Phosphatome in Colorectal Cancers , 2004, Science.
[58] E. Luebeck,et al. Multistage carcinogenesis and the incidence of human cancer , 2003, Genes, chromosomes & cancer.
[59] M. King,et al. Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2 , 2003, Science.
[60] Jason H Bielas,et al. Elevated mutagenesis and decreased DNA repair at a transgene are associated with proliferation but not apoptosis in p53-deficient cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[61] T. Golub. Mining the genome for combination therapies , 2003, Nature Medicine.
[62] K. Loeb,et al. Multiple mutations and cancer , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[63] C. Ulrich,et al. Polymorphisms in DNA repair genes and associations with cancer risk. , 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[64] P. Hanawalt,et al. Ultraviolet-sensitive syndrome cells are defective in transcription-coupled repair of cyclobutane pyrimidine dimers. , 2002, DNA repair.
[65] J. Coxhead,et al. Mutations in APC, Kirsten-ras, and p53—alternative genetic pathways to colorectal cancer , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[66] J. Stringer,et al. Embryonic stem cells and somatic cells differ in mutation frequency and type , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[67] Giovanni Parmigiani,et al. Prevalence of somatic alterations in the colorectal cancer cell genome , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[68] Alison L. Livingston,et al. Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors , 2002, Nature Genetics.
[69] I. Weissman,et al. Stem cells, cancer, and cancer stem cells , 2001, Nature.
[70] J. Hoeijmakers. Genome maintenance mechanisms for preventing cancer , 2001, Nature.
[71] T. Lindahl,et al. Quality control by DNA repair. , 1999, Science.
[72] S. Hecht,et al. Tobacco smoke carcinogens and lung cancer. , 1999, Journal of the National Cancer Institute.
[73] P. Jeggo,et al. Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient , 1999, Current Biology.
[74] F. Hanaoka,et al. Xeroderma pigmentosum variant (XP‐V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity , 1999, The EMBO journal.
[75] Carissa A. Sanchez,et al. Evolution of neoplastic cell lineages in Barrett oesophagus , 1999, Nature Genetics.
[76] M. Speicher,et al. Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[77] G. Marsischky,et al. Eukaryotic DNA mismatch repair. , 1999, Current opinion in genetics & development.
[78] K. Kinzler,et al. Genetic instabilities in human cancers , 1998, Nature.
[79] S. Knuutila,et al. DNA copy number changes in development and progression in leiomyosarcomas of soft tissues. , 1998, The American journal of pathology.
[80] C. Griffin,et al. Genetic analysis of ovarian germ cell tumors by comparative genomic hybridization. , 1998, Cancer research.
[81] A. Jackson,et al. The mutation rate and cancer. , 1998, Genetics.
[82] D. Birnbaum,et al. Genome-wide search for loss of heterozygosity shows extensive genetic diversity of human breast carcinomas. , 1997, Cancer research.
[83] A. Levine. p53, the Cellular Gatekeeper for Growth and Division , 1997, Cell.
[84] M. Chung,et al. Increased oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa. , 1996, Cancer research.
[85] N. Ellis,et al. The Bloom's syndrome gene product is homologous to RecQ helicases , 1995, Cell.
[86] G. Merlino,et al. Overexpression of transforming growth factor-alpha causes liver enlargement and increased hepatocyte proliferation in transgenic mice. , 1994, The American journal of pathology.
[87] J Piper,et al. Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[88] T. Petes,et al. Instability of simple sequence repeats in a mammalian cell line. , 1994, Human molecular genetics.
[89] L. Loeb,et al. Oxygen radical induced mutagenesis is DNA polymerase specific. , 1994, Journal of molecular biology.
[90] C. Harris,et al. p53: at the crossroads of molecular carcinogenesis and risk assessment. , 1993, Science.
[91] R. Floyd. Measurement of oxidative stress in vivo , 1993 .
[92] Y. Nakamura,et al. Genetic alterations during colorectal-tumor development. , 1988, The New England journal of medicine.
[93] M. Boehnke,et al. Estimation of mutation rates based on the analysis of polypeptide constituents of cultured human lymphoblastoid cells. , 1988, Genetics.
[94] M. Goodman,et al. Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[95] K E Warner,et al. Smoking and lung cancer: an overview. , 1984, Cancer research.
[96] T. Kunkel,et al. Depurination-induced infidelity of deoxyribonucleic acid synthesis with purified deoxyribonucleic acid replication proteins in vitro. , 1983, Biochemistry.
[97] P. Nowell. The clonal evolution of tumor cell populations. , 1976, Science.
[98] I. Lehman,et al. Biochemical characterization of mutant forms of DNA polymerase I from Escherichia coli. I. The polA12 mutation. , 1976, The Journal of biological chemistry.
[99] John Cairns,et al. Mutation selection and the natural history of cancer , 1975, Nature.
[100] L. Loeb,et al. Errors in DNA replication as a basis of malignant changes. , 1974, Cancer research.
[101] P. Rous. Transmission of a malignant new growth by means of a cell-free filtrate. , 1973, Connecticut medicine.
[102] B. Ames,et al. Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection. , 1973, Proceedings of the National Academy of Sciences of the United States of America.
[103] J. Cleaver. Defective Repair Replication of DNA in Xeroderma Pigmentosum , 1968, Nature.
[104] A. George. The metabolic basis of inherited disease , 1961 .
[105] R. Prehn,et al. Immunity to methylcholanthrene-induced sarcomas. , 1957, Journal of the National Cancer Institute.
[106] P. Armitage,et al. The Age Distribution of Cancer and a Multi-stage Theory of Carcinogenesis , 1954, British Journal of Cancer.
[107] E. A. Graham,et al. Tobacco smoking as a possible etiologic factor in bronchiogenic carcinoma. , 1950, Bulletin of the World Health Organization.
[108] E. A. Graham,et al. Tobacco smoking as a possible etiologic factor in bronchiogenic carcinoma; a study of 684 proved cases. , 1950, Journal of the American Medical Association.
[109] J. Robson,et al. Chemical Production of Mutations , 1946, Nature.
[110] Reinhard Wolf,et al. Coding-Sequence Determinants of Gene Expression in Escherichia coli , 2009 .
[111] F. Ducray,et al. IDH1 and IDH2 mutations in gliomas. , 2009, The New England journal of medicine.
[112] A. Levine,et al. The First Twenty-Five Years of p53 Research , 2007 .
[113] A. Knudson. Hereditary cancer: Two hits revisited , 2005, Journal of Cancer Research and Clinical Oncology.
[114] E. Hecker. Phorbol esters from croton oil chemical nature and biological activities , 2004, The Science of Nature.
[115] Robert DeMars,et al. The spontaneous azaguanine-resistant mutants of diploid human fibroblasts , 2004, Humangenetik.
[116] Giovanni Parmigiani,et al. Mutational Analysis of the Tyrosine Kinome in Colorectal Cancers , 2003, Nature Reviews Cancer.
[117] P. Modrich,et al. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. , 1996, Annual review of biochemistry.
[118] A. Balmain,et al. How many mutations are required for tumorigenesis? implications from human cancer data , 1993 .
[119] N. Fausto,et al. Mechanisms of growth regulation in liver regeneration and hepatic carcinogenesis. , 1993, Progress in liver diseases.
[120] R. Albertini,et al. In vivo somatic mutations in humans: measurement and analysis. , 1990, Annual review of genetics.
[121] L. Loeb,et al. Chapter 15 - KINETIC AND MAGNETIC RESONANCE STUDIES OF THE INTERACTION OF Mn 2+ , SUBSTRATES AND TEMPLATES WITH DNA POLYMERASES , 1986 .
[122] P. Nowell,et al. Karyotypic evolution in human malignant melanoma. , 1986, Cancer genetics and cytogenetics.
[123] F. Wedler,et al. Manganese in metabolism and enzyme function , 1986 .
[124] H. Varmus,et al. Synthesis, structure, and integration of the DNA of RNA tumor viruses. , 1979, Cold Spring Harbor symposia on quantitative biology.