ED overcrowding is associated with an increased frequency of medication errors.

OBJECTIVES Despite the growing problems of emergency department (ED) crowding, the potential impact on the frequency of medication errors occurring in the ED is uncertain. Using a metric to measure ED crowding in real time (the Emergency Department Work Index, or EDWIN, score), we sought to prospectively measure the correlation between the degree of crowding and the frequency of medication errors occurring in our ED as detected by our ED pharmacists. METHODS We performed a prospective, observational study in a large, community hospital ED of all patients whose medication orders were evaluated by our ED pharmacists for a 3-month period. Our ED pharmacists review the orders of all patients in the ED critical care section and the Chest Pain unit, and all admitted patients boarding in the ED. We measured the Spearman correlation between average daily EDWIN score and number of medication errors detected and determined the score's predictive performance with receiver operating characteristic (ROC) curves. RESULTS A total of 283 medication errors were identified by the ED pharmacists over the study period. Errors included giving medications at incorrect doses, frequencies, durations, or routes and giving contraindicated medications. Error frequency showed a positive correlation with daily average EDWIN score (Spearman's rho = 0.33; P = .001). The area under the ROC curve was 0.67 (95% confidence interval, 0.56-0.78) with failure defined as greater than 1 medication error per day. CONCLUSIONS We identified an increased frequency of medication errors in our ED with increased crowding as measured with a real-time modified EDWIN score.

[1]  Dominik Aronsky,et al.  The Epidemiology of Medication Prescribing Errors in the Emergency Department , 2006, AMIA.

[2]  R. Wuerz,et al.  Decrease in medical command errors with use of a "standing orders" protocol system. , 1994, The American journal of emergency medicine.

[3]  K. Rhodes,et al.  Safety net research in emergency medicine: proceedings of the Academic Emergency Medicine Consensus Conference on "The Unraveling Safety Net". , 2001, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[4]  D. Kyriacou,et al.  Errors in emergency medicine: research strategies. , 2000, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[5]  G. Koren,et al.  Medication errors in children. , 2006, Pediatric clinics of North America.

[6]  I. Singh,et al.  The Boarders in the Emergency Department (BED) study , 2008, Emergency Medicine Journal.

[7]  Robert L Wears,et al.  Beyond "communication failure". , 2009, Annals of emergency medicine.

[8]  Robert L Wears,et al.  The error of counting "errors". , 2008, Annals of emergency medicine.

[9]  T. Brennan,et al.  The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. , 1991, The New England journal of medicine.

[10]  J. Richards,et al.  Overcrowding in the nation's emergency departments: complex causes and disturbing effects. , 2000, Annals of emergency medicine.

[11]  D. Aronsky,et al.  Systematic review of emergency department crowding: causes, effects, and solutions. , 2008, Annals of emergency medicine.

[12]  N. Dickey,et al.  Systems analysis of adverse drug events. , 1996, JAMA.

[13]  G. Larkin,et al.  Emergency physicians and disclosure of medical errors. , 2006, Annals of emergency medicine.

[14]  L. Kohn,et al.  To Err Is Human : Building a Safer Health System , 2007 .

[15]  Dominik Aronsky,et al.  The emergency department occupancy rate: a simple measure of emergency department crowding? , 2008, Annals of emergency medicine.

[16]  E. Oren,et al.  Impact of emerging technologies on medication errors and adverse drug events. , 2003, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[17]  Overcrowding: not just an emergency department issue. , 2005 .

[18]  A Russell Localio,et al.  The association between emergency department crowding and hospital performance on antibiotic timing for pneumonia and percutaneous intervention for myocardial infarction. , 2006, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[19]  D. Eitel,et al.  Reliability and validity of a new five-level triage instrument. , 2000, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[20]  Pat Croskerry,et al.  Profiles in patient safety: medication errors in the emergency department. , 2004, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[21]  J. Feldman Medical Errors and Emergency Medicine: Will the Difficult Questions Be Asked, and Answered? , 2003 .

[22]  K. Cosby,et al.  A framework for classifying factors that contribute to error in the emergency department. , 2003, Annals of emergency medicine.

[23]  L L Leape,et al.  Human error in emergency medicine. , 1999, Annals of emergency medicine.

[24]  P. Croskerry,et al.  Emergency medicine: A practice prone to error? , 2001, CJEM.

[25]  D. Richardson,et al.  Increase in patient mortality at 10 days associated with emergency department overcrowding , 2006, The Medical journal of Australia.

[26]  Howard A Smithline,et al.  Errors in a busy emergency department. , 2003, Annals of emergency medicine.

[27]  P. Levy,et al.  The effect of clinical experience on the error rate of emergency physicians. , 2008, Annals of emergency medicine.

[28]  Marian Vermeulen,et al.  Emergency department crowding and thrombolysis delays in acute myocardial infarction. , 2004, Annals of emergency medicine.

[29]  Cherri Hobgood,et al.  Error identification, disclosure, and reporting: practice patterns of three emergency medicine provider types. , 2004, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[30]  Peter Bacchetti,et al.  Effect of emergency department crowding on time to antibiotics in patients admitted with community-acquired pneumonia. , 2007, Annals of emergency medicine.

[31]  John Concato,et al.  Care in the emergency department: how crowded is overcrowded? , 2004, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[32]  Jeremiah D Schuur,et al.  Dropping the baton: a qualitative analysis of failures during the transition from emergency department to inpatient care. , 2009, Annals of emergency medicine.

[33]  Steven L Bernstein,et al.  Development and validation of a new index to measure emergency department crowding. , 2003, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[34]  R. Wears,et al.  Human error in medicine: promise and pitfalls, part 1. , 2000, Annals of emergency medicine.

[35]  S. Trzeciak,et al.  Emergency department overcrowding in the United States: an emerging threat to patient safety and public health , 2003, Emergency medicine journal : EMJ.

[36]  Shari J. Welch,et al.  An independent evaluation of four quantitative emergency department crowding scales. , 2006, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[37]  G. Jelinek,et al.  The association between hospital overcrowding and mortality among patients admitted via Western Australian emergency departments , 2006, The Medical journal of Australia.

[38]  Kathleen O'neill,et al.  Patient misidentification in a pediatric emergency department: patient safety and legal perspectives. , 2004, Pediatric emergency care.

[39]  A. Wall,et al.  Book ReviewTo Err is Human: building a safer health system Kohn L T Corrigan J M Donaldson M S Washington DC USA: Institute of Medicine/National Academy Press ISBN 0 309 06837 1 $34.95 , 2000 .

[40]  Ò. Miró,et al.  Decreased health care quality associated with emergency department overcrowding. , 1999, European journal of emergency medicine : official journal of the European Society for Emergency Medicine.

[41]  Stacey L Cole,et al.  Medication errors among acutely ill and injured children treated in rural emergency departments. , 2007, Annals of emergency medicine.

[42]  N. Rathlev,et al.  Emergency Department overcrowding and ambulance diversion: the impact and potential solutions of extended boarding of admitted patients in the Emergency Department. , 2006, The Journal of emergency medicine.

[43]  A L Kellermann,et al.  Human error in medicine: promise and pitfalls, part 2. , 2000, Annals of emergency medicine.

[44]  Arthur L Kellermann,et al.  Crisis in the emergency department. , 2006, The New England journal of medicine.

[45]  Jane Garbutt,et al.  Patient concerns about medical errors in emergency departments. , 2005, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[46]  S D Berns,et al.  The potential for improved teamwork to reduce medical errors in the emergency department. The MedTeams Research Consortium. , 1999, Annals of emergency medicine.

[47]  D. Bates,et al.  Systems analysis of adverse drug events. ADE Prevention Study Group. , 1995, JAMA.

[48]  J. Richards,et al.  Emergency Department Overcrowding in Florida, New York, and Texas , 2002, Southern medical journal.

[49]  S. Epstein,et al.  Development of an emergency department work score to predict ambulance diversion. , 2006 .

[50]  S. Schenkel Promoting patient safety and preventing medical error in emergency departments. , 2000, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[51]  W. Cordell,et al.  Emergency department workplace interruptions: are emergency physicians "interrupt-driven" and "multitasking"? , 2000, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[52]  R. Steele,et al.  EMDOC (Emergency Department overcrowding) Internet-based safety net research. , 2008, The Journal of emergency medicine.

[53]  R. Wears,et al.  Errors in emergency medicine: a call to action. , 2000, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[54]  Howard A Peth Medication errors in the emergency department: a systems approach to minimizing risk. , 2003, Emergency medicine clinics of North America.

[55]  Todd G Nick,et al.  Comparison of the National Emergency Department Overcrowding Scale and the Emergency Department Work Index for quantifying emergency department crowding. , 2006, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[56]  Thomas G McCarter,et al.  Reducing Medication Errors , 2003, Drug safety.

[57]  M. Gillam,et al.  Defining, identifying, and measuring error in emergency medicine. , 2000, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.