Two subtypes of intervertebral disc degeneration distinguished by large-scale population-based study.

[1]  K. Luk,et al.  Intervertebral disc "dysgeneration". , 2015, The spine journal : official journal of the North American Spine Society.

[2]  Huilin Yang,et al.  Regional Variations in the Cellular, Biochemical, and Biomechanical Characteristics of Rabbit Annulus Fibrosus , 2014, PloS one.

[3]  P. O’Reilly,et al.  Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant. , 2013, The Journal of clinical investigation.

[4]  J. Niinimäki,et al.  Association of Abdominal Obesity with Lumbar Disc Degeneration – A Magnetic Resonance Imaging Study , 2013, PloS one.

[5]  Bernadette A. Thomas,et al.  Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 , 2012, The Lancet.

[6]  M. Adams,et al.  Intervertebral disc degeneration: evidence for two distinct phenotypes , 2012, Journal of anatomy.

[7]  N. Tommerup,et al.  Genetic Association Studies in Lumbar Disc Degeneration: A Systematic Review , 2012, PloS one.

[8]  M. Battié,et al.  Modic changes: prevalence, distribution patterns, and association with age in white men. , 2012, The spine journal : official journal of the North American Spine Society.

[9]  K. Cheung,et al.  Are “Patterns” of Lumbar Disc Degeneration Associated With Low Back Pain?: New Insights Based on Skipped Level Disc Pathology , 2012, Spine.

[10]  J. Niinimäki,et al.  Does Lumbar Disc Degeneration on Magnetic Resonance Imaging Associate With Low Back Symptom Severity in Young Finnish Adults? , 2011, Spine.

[11]  G. Andersson,et al.  Management of degenerative disk disease and chronic low back pain. , 2011, The Orthopedic clinics of North America.

[12]  K. Cheung,et al.  A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status. , 2011, The Journal of bone and joint surgery. American volume.

[13]  H. Wilke,et al.  The mechanical response of the lumbar spine to different combinations of disc degenerative changes investigated using randomized poroelastic finite element models , 2011, European Spine Journal.

[14]  P. Visscher,et al.  GCTA: a tool for genome-wide complex trait analysis. , 2011, American journal of human genetics.

[15]  K. Cheung,et al.  ISSLS Prize Winner: Prevalence, Determinants, and Association of Schmorl Nodes of the Lumbar Spine With Disc Degeneration: A Population-Based Study of 2449 Individuals , 2010, Spine.

[16]  K. Cheung,et al.  Intervertebral disc degeneration: new insights based on "skipped" level disc pathology. , 2010, Arthritis and rheumatism.

[17]  S. Peleg,et al.  Schmorl’s nodes distribution in the human spine and its possible etiology , 2010, European Spine Journal.

[18]  A. Hofman,et al.  The Association Between Lumbar Disc Degeneration and Low Back Pain: The Influence of Age, Gender, and Individual Radiographic Features , 2010, Spine.

[19]  P. Kjaer,et al.  Characteristics and natural course of vertebral endplate signal (Modic) changes in the Danish general population , 2009, BMC musculoskeletal disorders.

[20]  Jaro Karppinen,et al.  Prevalence and Pattern of Lumbar Magnetic Resonance Imaging Changes in a Population Study of One Thousand Forty-Three Individuals , 2009, Spine.

[21]  J. Kaprio,et al.  Genetic and Environmental Effects on Disc Degeneration by Phenotype and Spinal Level: A Multivariate Twin Study , 2008, Spine.

[22]  J. Kaprio,et al.  Heritability of low back pain and the role of disc degeneration , 2007, PAIN.

[23]  Hans-Joachim Wilke,et al.  Review of existing grading systems for cervical or lumbar disc and facet joint degeneration , 2006, European Spine Journal.

[24]  Lutz Claes,et al.  Validity and interobserver agreement of a new radiographic grading system for intervertebral disc degeneration: Part I. Lumbar spine , 2006, European Spine Journal.

[25]  Gunnar B J Andersson,et al.  Recent Advances in Analytical Modeling of Lumbar Disc Degeneration , 2004, Spine.

[26]  C. Pfirrmann,et al.  Magnetic Resonance Classification of Lumbar Intervertebral Disc Degeneration , 2001, Spine.

[27]  K. Palmer,et al.  Back pain in Britain: comparison of two prevalence surveys at an interval of 10 years , 2000, BMJ : British Medical Journal.

[28]  E Viikari-Juntura,et al.  Low back pain in relation to lumbar disc degeneration. , 2000, Spine.

[29]  W. Halperin,et al.  Back pain prevalence in US industry and estimates of lost workdays. , 1999, American journal of public health.

[30]  T. Spector,et al.  Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins. , 1999, Arthritis and rheumatism.

[31]  E. Viikari-Juntura,et al.  Lumbar disc degeneration in relation to occupation. , 1998, Scandinavian journal of work, environment & health.

[32]  M. Battié,et al.  Determinants of Lumbar Disc Degeneration: A Study Relating Lifetime Exposures and Magnetic Resonance Imaging Findings in Identical Twins , 1995, Spine.

[33]  P M Bentler,et al.  A two-stage estimation of structural equation models with continuous and polytomous variables. , 1995, The British journal of mathematical and statistical psychology.

[34]  T Videman,et al.  The Long‐Term Effects of Physical Loading and Exercise Lifestyles on Back‐Related Symptoms, Disability, and Spinal Pathology Among Men , 1995, Spine.

[35]  J. Kaprio,et al.  1991 Volvo Award in Clinical Sciences: Smoking and Lumbar Intervertebral Disc Degeneration: An MRI Study of Identical Twins , 1991, Spine.

[36]  J. Zucherman,et al.  High Lumbar Disc Degeneration Incidence and Etiology , 1990, Spine.

[37]  M M Panjabi,et al.  Regional Variations in the Compressive Properties of Lumbar Vertebral Trabeculae: Effects of Disc Degeneration , 1989, Spine.

[38]  W. Cleveland,et al.  Locally Weighted Regression: An Approach to Regression Analysis by Local Fitting , 1988 .

[39]  A. Schultz,et al.  Lumbar Disc Degeneration: Correlation with Age, Sex, and Spine Level in 600 Autopsy Specimens , 1988, Spine.

[40]  B. Flannigan,et al.  Magnetic Resonance Imaging in the Diagnosis of Disc Degeneration: Correlation with Discography , 1987, Spine.

[41]  A. Zellner.  An Efficient Method of Estimating Seemingly Unrelated Regressions and Tests for Aggregation Bias , 1962 .

[42]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[43]  Leena Peltonen,et al.  The Twin Spine Study: contributions to a changing view of disc degeneration. , 2009, The spine journal : official journal of the North American Spine Society.

[44]  J. Caro,et al.  A systematic review of low back pain cost of illness studies in the United States and internationally. , 2008, The spine journal : official journal of the North American Spine Society.