The tuned mass damper (TMD) for vibration control of tower subjected to multi-dimensional seismic excitations is studied in this paper. Calculation model of the tuned mass damper is introduced, and the equations of motion of a tower with tuned mass damper are derived, and the calculation parameters of the tuned mass damper are given based on the control structure. According to a practical engineering, the three-dimensional finite element model of a tower is established using SAP2000. Three typical seismic records are selected according the code of seismic design. Vibration control for tower model with tuned mass damper under multi-dimensional seismic excitations is performed by using numerical simulation. The maximum responses of displacement and axial force of the tower structure without and with TMD are obtained. The results show that the TMD could decrease the responses of the tower in three directions, and the tower with TMD can be a reference for tower practice engineering application.