A Novel Approach to Fiber-Optic Tweezers: Numerical Analysis of the Trapping Efficiency

We present a novel all-fiber optical tweezer (OT) for biological applications. The tweezer is based on a new approach relying on total internal reflection in an annular core fiber or into a fiber bundle. The proposed device, whose trapping efficacy has been recently demonstrated experimentally, is extremely promising, also because optical manipulation and analysis functions can be easily added to the tweezer basic structure, leading to the realization of a powerful biotool. In this paper, a detailed numerical analysis of the structure properties and of its efficiency is carried out in the Mie regime. Moreover, by defining a new parameter to evaluate the trapping efficiency, we perform a comparison between the proposed tweezer structure and a standard OT based on a strongly focused Gaussian beam.

[1]  R. Taylor,et al.  Particle trapping in 3-D using a single fiber probe with an annular light distribution. , 2003, Optics express.

[2]  Jonathan Leach,et al.  An optical trapped microhand for manipulating micron-sized objects. , 2006, Optics express.

[3]  Francesco De Angelis,et al.  Miniaturized all-fibre probe for three-dimensional optical trapping and manipulation , 2007 .

[4]  Zhaohui Hu,et al.  Manipulation and arrangement of biological and dielectric particles by a lensed fiber probe. , 2004, Optics express.

[5]  A. Ashkin Acceleration and trapping of particles by radiation pressure , 1970 .

[6]  Giovanni Volpe,et al.  Raman imaging of floating cells. , 2005, Optics express.

[7]  K. Taguchi,et al.  Optical trapping of dielectric particle and biological cell using optical fibre , 1997 .

[8]  A. Ashkin Forces of a single-beam gradient laser trap on a dielectric sphere in the ray optics regime. , 1992, Methods in cell biology.

[9]  B. Hecht,et al.  Principles of nano-optics , 2006 .

[10]  D. Grier A revolution in optical manipulation , 2003, Nature.

[11]  I. Adesida,et al.  High transconductance AlGaN/GaN heterostructure field effect transistors on SiC substrates , 1997 .

[12]  Dan Cojoc,et al.  Wave front engineering for microscopy of living cells. , 2005, Optics express.

[13]  Lukas Novotny,et al.  Principles of Nano-Optics by Lukas Novotny , 2006 .

[14]  Mattias Goksör,et al.  Optical manipulation in combination with multiphoton microscopy for single-cell studies. , 2004, Applied optics.

[15]  Libo Yuan,et al.  Tapered fiber optical tweezers for microscopic particle trapping: fabrication and application. , 2006, Optics express.

[16]  U. Bockelmann,et al.  Unzipping DNA with optical tweezers: high sequence sensitivity and force flips. , 2002, Biophysical journal.