Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site.
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E Westhof | E. Westhof | Q. Vicens | Q Vicens
[1] G. Wright,et al. Aminoglycoside antibiotics. Structures, functions, and resistance. , 1998, Advances in experimental medicine and biology.
[2] Thomas A. Steitz,et al. RNA tertiary interactions in the large ribosomal subunit: The A-minor motif , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[3] S. Harvey,et al. Major groove binding of the tRNA/mRNA complex to the 16 S ribosomal RNA decoding site. , 1999, Journal of molecular biology.
[4] Z. Otwinowski,et al. [20] Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.
[5] J. Puglisi,et al. Structure of the A Site of Escherichia coli 16S Ribosomal RNA Complexed with an Aminoglycoside Antibiotic , 1996, Science.
[6] Structure of a 16-mer RNA duplex r(GCAGACUUAAAUCUGC)2 with wobble C.A+ mismatches. , 1998, Journal of molecular biology.
[7] Harry F. Noller,et al. Interaction of antibiotics with functional sites in 16S ribosomal RNA , 1987, Nature.
[8] E. Westhof,et al. Aminoglycoside-RNA interactions. , 1999, Current opinion in chemical biology.
[9] S. Stern,et al. Interactions of a small RNA with antibiotic and RNA ligands of the 30S subunit , 1994, Nature.
[10] J. Puglisi,et al. Structural origins of gentamicin antibiotic action , 1998, The EMBO journal.
[11] D. Patel,et al. Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex. , 1997, Chemistry & biology.
[12] T. Pape,et al. Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome , 2000, Nature Structural Biology.
[13] Jennifer A. Doudna,et al. A universal mode of helix packing in RNA , 2001, Nature Structural Biology.
[14] J. Puglisi,et al. Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 S rRNA. , 1998, Journal of molecular biology.
[15] J. Puglisi,et al. Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA. , 1998, Journal of molecular biology.
[16] W D Wilson,et al. Targeting RNA with small molecules. , 2000, Current medicinal chemistry.
[17] J. Puglisi,et al. Basis for prokaryotic specificity of action of aminoglycoside antibiotics , 1999, The EMBO journal.
[18] Collaborative Computational,et al. The CCP4 suite: programs for protein crystallography. , 1994, Acta crystallographica. Section D, Biological crystallography.
[19] J. Puglisi,et al. rRNA chemical groups required for aminoglycoside binding. , 1998, Biochemistry.
[20] L. Pannell,et al. 6-Aza-2-thiothymine: a matrix for MALDI spectra of oligonucleotides. , 1995, Nucleic acids research.
[21] V. Ramakrishnan,et al. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics , 2000, Nature.
[22] V. Ramakrishnan,et al. Crystal structure of an initiation factor bound to the 30S ribosomal subunit. , 2001, Science.
[23] S. Yokoyama,et al. An antibiotic-binding motif of an RNA fragment derived from the A-site-related region of Escherichia coli 16S rRNA. , 1996, Nucleic acids research.
[24] K. Waltersson,et al. The crystal structure of Cs[VOF3] · 12H2O , 1979 .
[25] J. Navaza,et al. AMoRe: an automated package for molecular replacement , 1994 .
[26] I. Siemion,et al. New hypothesis on amino acid complementarity and its evaluation on TGF‐β2‐related peptides , 2001, Journal of molecular recognition : JMR.
[27] G J Kleywegt,et al. Where freedom is given, liberties are taken. , 1995, Structure.
[28] E Westhof,et al. Water and ion binding around RNA and DNA (C,G) oligomers. , 2000, Journal of molecular biology.
[29] Philip R. Evans,et al. Crystal structure of the spliceosomal U2B″–U2A′ protein complex bound to a fragment of U2 small nuclear RNA , 1998, Nature.
[30] E. Westhof,et al. RNA tectonics: towards RNA design. , 1996, Folding & design.
[31] E. Westhof,et al. Aminoglycoside binding to the hammerhead ribozyme: a general model for the interaction of cationic antibiotics with RNA. , 1998, Journal of molecular biology.
[32] E Westhof,et al. Conserved geometrical base-pairing patterns in RNA , 1998, Quarterly Reviews of Biophysics.
[33] C. Vonrhein,et al. Structure of the 30S ribosomal subunit , 2000, Nature.
[34] V. Ramakrishnan,et al. Recognition of Cognate Transfer RNA by the 30S Ribosomal Subunit , 2001, Science.
[35] P. Moore,et al. Structural motifs in RNA. , 1999, Annual review of biochemistry.
[36] E Westhof,et al. Docking of cationic antibiotics to negatively charged pockets in RNA folds. , 1999, Journal of medicinal chemistry.
[37] G J Kleywegt,et al. Model building and refinement practice. , 1997, Methods in enzymology.
[38] T. Steitz,et al. Metals, Motifs, and Recognition in the Crystal Structure of a 5S rRNA Domain , 1997, Cell.
[39] Hermann. Strategies for the Design of Drugs Targeting RNA and RNA-Protein Complexes. , 2000, Angewandte Chemie.
[40] J. Sabina,et al. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. , 1999, Journal of molecular biology.
[41] E. Cundliffe,et al. Sites of action of two ribosomal RNA methylases responsible for resistance to aminoglycosides. , 1987, Journal of molecular biology.
[42] E. Westhof,et al. RNA folding: beyond Watson-Crick pairs. , 2000, Structure.
[43] S V Evans,et al. SETOR: hardware-lighted three-dimensional solid model representations of macromolecules. , 1993, Journal of molecular graphics.
[44] C Massire,et al. MANIP: an interactive tool for modelling RNA. , 1998, Journal of molecular graphics & modelling.
[45] C. Ehresmann,et al. The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges. , 1999, Structure.
[46] J. Puglisi,et al. Recognition of the codon-anticodon helix by ribosomal RNA. , 1999, Science.
[47] T. Steitz,et al. The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. , 2000, Science.
[48] K. Flaherty,et al. Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetraloop and an RNA helix , 1994, Nature.
[49] C. Wong,et al. Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA. , 1998, Chemistry & biology.
[50] J Davies,et al. Bacterial resistance to aminoglycoside antibiotics. , 1997, The Journal of infectious diseases.
[51] R. Green,et al. Ribosomal Rna and Group I Introns , 1996 .
[52] B. Coxon,et al. Nitrogen-15 nuclear magnetic resonance spectroscopy of neomycin B and related aminoglycosides , 1983 .
[53] E. Westhof,et al. Hydration of transfer RNA molecules: a crystallographic study. , 1988, Biochimie.
[54] J. Davies,et al. Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics. The effect of drug concentration. , 1968, The Journal of biological chemistry.
[55] C Massire,et al. DRAWNA: a program for drawing schematic views of nucleic acids. , 1994, Journal of molecular graphics.
[56] S. Mobashery,et al. Resolving the antibiotic paradox: progress in understanding drug resistance and development of new antibiotics. , 1998 .
[57] E. Westhof,et al. Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis. , 1990, Journal of molecular biology.
[58] R J Read,et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.
[59] J. Puglisi,et al. RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide. , 1996, Journal of molecular biology.
[60] Batey,et al. Tertiary Motifs in RNA Structure and Folding. , 1999, Angewandte Chemie.
[61] E Westhof,et al. Statistical analysis of atomic contacts at RNA–protein interfaces , 2001, Journal of molecular recognition : JMR.
[62] U Heinemann,et al. Crystal structure of an RNA dodecamer containing the Escherichia coli Shine-Dalgarno sequence. , 1995, Journal of molecular biology.
[63] T. Steitz,et al. Crystal structures of three misacylating mutants of Escherichia coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP. , 1996, Biochemistry.