The HSF1–PARP13–PARP1 complex facilitates DNA repair and promotes mammary tumorigenesis

[1]  Fabiana M. Duarte,et al.  Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation. , 2016, Molecular cell.

[2]  H. van Attikum,et al.  PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining , 2016, Molecular cell.

[3]  Alan Ashworth,et al.  BRCAness revisited , 2016, Nature Reviews Cancer.

[4]  D. Thiele,et al.  Structures of HSF2 Reveal Mechanisms for Differential Regulation of Human Heat Shock Factors , 2016, Nature Structural &Molecular Biology.

[5]  Andreas Bracher,et al.  Structure of human heat-shock transcription factor 1 in complex with DNA , 2016, Nature Structural &Molecular Biology.

[6]  A. Nakai Heat Shock Factor , 2016, Springer Japan.

[7]  F. Miozzo,et al.  HSFs, Stress Sensors and Sculptors of Transcription Compartments and Epigenetic Landscapes. , 2015, Journal of molecular biology.

[8]  J. Pascal,et al.  Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1 , 2015, Molecular cell.

[9]  Peter Bai,et al.  Biology of Poly(ADP-Ribose) Polymerases: The Factotums of Cell Maintenance. , 2015, Molecular cell.

[10]  R. Morimoto,et al.  The biology of proteostasis in aging and disease. , 2015, Annual review of biochemistry.

[11]  F. Bock,et al.  Poly(ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer. , 2015, Trends in molecular medicine.

[12]  Peter Bouwman,et al.  REV7 counteracts DNA double-strand break resection and affects PARP inhibition , 2015, Nature.

[13]  S. Huang,et al.  Acetylation of HDAC1 and degradation of SIRT1 form a positive feedback loop to regulate p53 acetylation during heat-shock stress , 2015, Cell Death and Disease.

[14]  E. Zelin,et al.  Lysine deacetylases regulate the heat shock response including the age-associated impairment of HSF1. , 2015, Journal of molecular biology.

[15]  L. Shultz,et al.  MEK Guards Proteome Stability and Inhibits Tumor-Suppressive Amyloidogenesis via HSF1 , 2015, Cell.

[16]  K. Shirahige,et al.  ATF1 Modulates the Heat Shock Response by Regulating the Stress-Inducible Heat Shock Factor 1 Transcription Complex , 2014, Molecular and Cellular Biology.

[17]  M. Hipp,et al.  Proteostasis impairment in protein-misfolding and -aggregation diseases. , 2014, Trends in cell biology.

[18]  Uma M. Muthurajan,et al.  Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone , 2014, Proceedings of the National Academy of Sciences.

[19]  A. Kossenkov,et al.  Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark , 2014, Nucleic acids research.

[20]  J. Weissman,et al.  Differential Scales of Protein Quality Control , 2014, Cell.

[21]  A. Jeyasekharan,et al.  PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair , 2014, Proceedings of the National Academy of Sciences.

[22]  L. Sistonen,et al.  Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells , 2013, Proceedings of the National Academy of Sciences.

[23]  Sejal Vyas,et al.  A systematic analysis of the PARP protein family identifies new functions critical for cell physiology , 2013, Nature Communications.

[24]  Ryuichiro Nakato,et al.  DROMPA: easy-to-handle peak calling and visualization software for the computational analysis and validation of ChIP-seq data , 2013, Genes to cells : devoted to molecular & cellular mechanisms.

[25]  T. Natsume,et al.  RPA assists HSF1 access to nucleosomal DNA by recruiting histone chaperone FACT. , 2012, Molecular cell.

[26]  G. Castellano,et al.  CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells. , 2012, Genes & development.

[27]  Marc L. Mendillo,et al.  HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers , 2012, Cell.

[28]  J. Lis,et al.  Overcoming the nucleosome barrier during transcript elongation. , 2012, Trends in genetics : TIG.

[29]  J. Pascal,et al.  Structural Basis for DNA Damage–Dependent Poly(ADP-ribosyl)ation by Human PARP-1 , 2012, Science.

[30]  J. Lis,et al.  Activator-induced spread of poly(ADP-ribose) polymerase promotes nucleosome loss at Hsp70. , 2012, Molecular cell.

[31]  S. Messner,et al.  Histone ADP-ribosylation in DNA repair, replication and transcription. , 2011, Trends in cell biology.

[32]  Jesse D. Martinez,et al.  Loss of HSF1 Results in Defective Radiation-Induced G2 Arrest and DNA Repair , 2011, Radiation research.

[33]  H. Tauchi,et al.  Regulation of homologous recombination by RNF20-dependent H2B ubiquitination. , 2011, Molecular cell.

[34]  Bernhard Kuster,et al.  Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. , 2011, Molecular cell.

[35]  S. Jackson,et al.  Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. , 2011, Genes & development.

[36]  J. Buchner,et al.  The heat shock response: life on the verge of death. , 2010, Molecular cell.

[37]  S. Elledge,et al.  The DNA damage response: making it safe to play with knives. , 2010, Molecular cell.

[38]  S. Elledge,et al.  A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage , 2010, Proceedings of the National Academy of Sciences.

[39]  V. Mezger,et al.  Roles of heat shock factors in gametogenesis and development , 2010, The FEBS journal.

[40]  A. Nakai,et al.  The heat shock factor family and adaptation to proteotoxic stress , 2010, The FEBS journal.

[41]  R. Morimoto,et al.  Heat shock factors: integrators of cell stress, development and lifespan , 2010, Nature Reviews Molecular Cell Biology.

[42]  W. Kraus,et al.  The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. , 2010, Molecular cell.

[43]  Bernhard Lüscher,et al.  Toward a unified nomenclature for mammalian ADP-ribosyltransferases. , 2010, Trends in biochemical sciences.

[44]  M. Jarnik,et al.  Uncoupling of the transactivation and transrepression functions of PARP1 protein , 2010, Proceedings of the National Academy of Sciences.

[45]  Tsonwin Hai,et al.  Heat Shock Transcription Factor 1 Inhibits Expression of IL-6 through Activating Transcription Factor 3 , 2009, The Journal of Immunology.

[46]  J. Bartek,et al.  The DNA-damage response in human biology and disease , 2009, Nature.

[47]  S. West,et al.  Poly(ADP-ribose)–Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1 , 2009, Science.

[48]  K. Birukov,et al.  SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1 , 2009, Molecular and Cellular Biology.

[49]  D. Scheuner,et al.  Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development , 2009, Proceedings of the National Academy of Sciences.

[50]  Cole Trapnell,et al.  Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.

[51]  B. Hoffman,et al.  Gadd45 in stress signaling , 2008, Journal of molecular signaling.

[52]  J. Dahm-Daphi,et al.  Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks , 2008, Nucleic acids research.

[53]  S. Calderwood,et al.  Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1 , 2008, Oncogene.

[54]  W. Kraus,et al.  Reciprocal Binding of PARP-1 and Histone H1 at Promoters Specifies Transcriptional Outcomes , 2008, Science.

[55]  Tsonwin Hai,et al.  Heat Shock Transcription Factor 1 Opens Chromatin Structure of Interleukin-6 Promoter to Facilitate Binding of an Activator or a Repressor* , 2007, Journal of Biological Chemistry.

[56]  S. Lindquist,et al.  Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis , 2007, Cell.

[57]  W. Kraus,et al.  The DNA Binding and Catalytic Domains of Poly(ADP-Ribose) Polymerase 1 Cooperate in the Regulation of Chromatin Structure and Transcription , 2007, Molecular and Cellular Biology.

[58]  A. Harel-Bellan,et al.  The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity. , 2006, Genes & development.

[59]  Zhao-Qi Wang,et al.  Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts. , 2006, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[60]  A. Hollestelle,et al.  BRCA1 mutation analysis of 41 human breast cancer cell lines reveals three new deleterious mutants. , 2006, Cancer research.

[61]  William Arbuthnot Sir Lane,et al.  Acetylation of Poly(ADP-ribose) Polymerase-1 by p300/CREB-binding Protein Regulates Coactivation of NF-κB-dependent Transcription* , 2005, Journal of Biological Chemistry.

[62]  K. Isobe,et al.  Regulation of mouse GADD34 gene transcription after DNA damaging agent methylmethane sulfonate. , 2004, Gene.

[63]  J. Lis,et al.  PARP Goes Transcription , 2003, Cell.

[64]  S. Schreiber,et al.  Histone Deacetylase 1 Phosphorylation Promotes Enzymatic Activity and Complex Formation* , 2001, The Journal of Biological Chemistry.

[65]  T. Halazonetis,et al.  P53 Binding Protein 1 (53bp1) Is an Early Participant in the Cellular Response to DNA Double-Strand Breaks , 2000, The Journal of cell biology.

[66]  L. Thompson,et al.  XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. , 1999, Genes & development.

[67]  S. Schreiber,et al.  A role for histone deacetylase activity in HDAC1-mediated transcriptional repression. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[68]  D. Ward,et al.  Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[69]  K. Kohn,et al.  The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth , 1994, Molecular and cellular biology.

[70]  E. Craig,et al.  The heat shock response. , 1985, CRC critical reviews in biochemistry.