Optimal power deposition with finite-sized, planar hyperthermia applicator arrays

Effective utilization of planar applicator arrays requires an understanding of the interrelationships between the lateral dimensions of the tumor and the applicators, the power field produced by the applicators, the amount of surface cooling, the tumor tissue blood perfusion, and the normal tissue blood perfusion. These interrelationships are investigated using three-dimensional power patterns and temperature fields produced by optimizing the power amplitudes of the individual applicators located within an array of small, but finite, planar applicators. Five major conclusions are obtained and discussed.<<ETX>>

[1]  J. Ortega Introduction to Parallel and Vector Solution of Linear Systems , 1988, Frontiers of Computer Science.

[2]  C. Cain,et al.  The concentric-ring array for ultrasound hyperthermia: combined mechanical and electrical scanning. , 1990, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[3]  K. B. Ocheltree,et al.  Determination of power deposition patterns for localized hyperthermia: a steady-state analysis. , 1987, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[4]  J D Doss Simulation of automatic temperature control in tissue hyperthermia calculations. , 1985, Medical physics.

[5]  L. Frizzell,et al.  Analysis of a multielement ultrasound hyperthermia applicator , 1989, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[6]  R. Roemer Optimal power deposition in hyperthermia. I. The treatment goal: the ideal temperature distribution: the role of large blood vessels. , 1991, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[7]  M Knudsen,et al.  Two-point control of temperature profile in tissue. , 1986, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[8]  E. Burdette,et al.  Performance of a multi-sector ultrasound hyperthermia applicator and control system: in vivo studies. , 1990, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[9]  Giorgio A. Lovisolo,et al.  Focusing of 915 MHz Electromagnetic Power on Deep Human Tissues: A Mathematical Model Study , 1984, IEEE Transactions on Biomedical Engineering.

[10]  K. Hynynen,et al.  Scanned focussed ultrasound hyperthermia: Clinical response evaluation , 1990 .

[11]  J. Strohbehn,et al.  Control of the SAR Pattern Within an Interstitial Microwave Array through Variation of Antenna Driving Phase , 1986 .

[12]  K. Hynynen,et al.  Scanned focussed ultrasound hyperthermia: initial clinical results. , 1988, International journal of radiation oncology, biology, physics.

[13]  J. Overgaard,et al.  A Hyperthermia System Using a New Type of Inductive Applicator , 1984, IEEE Transactions on Biomedical Engineering.

[14]  R. Roemer,et al.  Three-dimensional simulations of ferromagnetic implant hyperthermia. , 1992, Medical physics.

[15]  T. Samulski,et al.  Spiral microstrip hyperthermia applicators: technical design and clinical performance. , 1990, International journal of radiation oncology, biology, physics.

[16]  C. D. Wagter,et al.  Optimization of Simulated Two-Dimensional Temperature Distributions Induced by Multiple Electromagnetic Applicators , 1986 .

[17]  Theoretical investigation of a phased-array hyperthermia system with movable apertures. , 1990, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[18]  James C. Lin SPECIAL ISSUE ON PHASED ARRAYS FOR HYPERTHERMIA TREATMENT OF CANCER , 1986 .

[19]  R. Roemer,et al.  Towards the estimation of three-dimensional temperature fields from noisy temperature measurements during hyperthermia. , 1989, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[20]  E. H. Curtis,et al.  Optimization of the absorbed power distribution for an annular phased array hyperthermia system. , 1989, International journal of radiation oncology, biology, physics.

[21]  Louis A. Hageman,et al.  Iterative Solution of Large Linear Systems. , 1971 .

[22]  P. P. Lele,et al.  Temperature distributions in tissues during local hyperthermia by stationary or steered beams of unfocused or focused ultrasound. , 1982, The British journal of cancer. Supplement.

[23]  R B Roemer,et al.  The effects of large blood vessels on temperature distributions during simulated hyperthermia. , 1992, Journal of biomechanical engineering.

[24]  R L Magin,et al.  A multi-element ultrasonic hyperthermia applicator with independent element control. , 1987, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.