Estrogen receptor alpha mediates 17β-estradiol, up-regulates autophagy and alleviates hydrogen peroxide-induced vascular senescence

[1]  J. Pitha,et al.  Cardiovascular, Metabolic and Inflammatory Changes after Ovariectomy and Estradiol Substitution in Hereditary Hypertriglyceridemic Rats , 2022, International journal of molecular sciences.

[2]  Steven H. Lin,et al.  Senescence-Associated Secretory Phenotype as a Hinge Between Cardiovascular Diseases and Cancer , 2021, Frontiers in Cardiovascular Medicine.

[3]  A. Pellicer,et al.  Estrogen Replacement Therapy Induces Antioxidant and Longevity-Related Genes in Women after Medically Induced Menopause , 2021, Oxidative medicine and cellular longevity.

[4]  Hiromi Kirisako,et al.  Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus , 2021, bioRxiv.

[5]  Jinbao Liu,et al.  Selective autophagy of intracellular organelles: recent research advances , 2021, Theranostics.

[6]  Wen Chen,et al.  Estrogen prevent atherosclerosis by attenuating endothelial cell pyroptosis via activation of estrogen receptor α-mediated autophagy , 2020, Journal of advanced research.

[7]  Saizhu Wu,et al.  17β-estradiol inhibits H2O2-induced senescence in HUVEC cells through upregulating SIRT3 expression and promoting autophagy , 2020, Biogerontology.

[8]  M. Holz,et al.  Unconventional Estrogen Signaling in Health and Disease. , 2020, Endocrinology.

[9]  A. Orekhov,et al.  The Diabetes Mellitus–Atherosclerosis Connection: The Role of Lipid and Glucose Metabolism and Chronic Inflammation , 2020, International journal of molecular sciences.

[10]  Hui Shen,et al.  A road map for understanding molecular and genetic determinants of osteoporosis , 2019, Nature Reviews Endocrinology.

[11]  G. Salazar,et al.  Protective Role of Polyphenols against Vascular Inflammation, Aging and Cardiovascular Disease , 2018, Nutrients.

[12]  Saizhu Wu,et al.  17β-estradiol inhibits human umbilical vascular endothelial cell senescence by regulating autophagy via p53 , 2018, Experimental Gerontology.

[13]  X. Long,et al.  Lactobacillus plantarum CQPC11 Isolated from Sichuan Pickled Cabbages Antagonizes d-galactose-Induced Oxidation and Aging in Mice , 2018, Molecules.

[14]  Jin Xiang,et al.  How does estrogen work on autophagy? , 2018, Autophagy.

[15]  G. Kroemer,et al.  Autophagy in Cardiovascular Aging. , 2018, Circulation research.

[16]  H. Kubo,et al.  Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells , 2018, Oxidative medicine and cellular longevity.

[17]  Jeroen J. Bax,et al.  Relationship of Hypertension to Coronary Atherosclerosis and Cardiac Events in Patients With Coronary Computed Tomographic Angiography , 2017, Hypertension.

[18]  K. Griendling,et al.  Zinc regulates Nox1 expression through a NF‐&kgr;B and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells , 2017, Free radical biology & medicine.

[19]  Ling-Qing Yuan,et al.  Oestrogen Inhibits Arterial Calcification by Promoting Autophagy , 2017, Scientific Reports.

[20]  R. Bast,et al.  Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression , 2017, Autophagy.

[21]  Xiaojing Jiang,et al.  1,25(OH)2D3 attenuates hepatic steatosis by inducing autophagy in mice , 2017, Obesity.

[22]  H. Lim,et al.  Autophagic regulation in steroid hormone-responsive systems , 2016, Steroids.

[23]  J. Simpkins,et al.  Reprint of: From the 90׳s to now: A brief historical perspective on more than two decades of estrogen neuroprotection , 2016, Brain Research.

[24]  S. Kimball,et al.  Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation. , 2016, Cellular signalling.

[25]  M. Marino,et al.  Dynamin II is required for 17β-estradiol signaling and autophagy-based ERα degradation , 2016, Scientific Reports.

[26]  Chaowei Lin,et al.  Inhibition of Autophagy by Estradiol Promotes Locomotor Recovery after Spinal Cord Injury in Rats , 2016, Neuroscience Bulletin.

[27]  T. Kondo,et al.  Exaggerated arsenic nephrotoxicity in female mice through estrogen-dependent impairments in the autophagic flux. , 2016, Toxicology.

[28]  A. Akhmedov,et al.  Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease. , 2015, European heart journal.

[29]  A. Yusof,et al.  Estrogen receptor (ER)-α, β and progesterone receptor (PR) mediates changes in relaxin receptor (RXFP1 and RXFP2) expression and passive range of motion of rats' knee. , 2015, Environmental toxicology and pharmacology.

[30]  W. Kuo,et al.  17β-Estradiol and/or Estrogen Receptor β Attenuate the Autophagic and Apoptotic Effects Induced by Prolonged Hypoxia Through HIF-1α-Mediated BNIP3 and IGFBP-3 Signaling Blockage , 2015, Cellular Physiology and Biochemistry.

[31]  K. Yanar,et al.  Oxidation scrutiny in persuaded aging and chronological aging at systemic redox homeostasis level , 2014, Experimental Gerontology.

[32]  W. Baumann,et al.  Knockdown of estrogen receptor‐α induces autophagy and inhibits antiestrogen‐mediated unfolded protein response activation, promoting ROS‐induced breast cancer cell death , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[33]  Jian Xiao,et al.  Estrogen protects cardiomyocytes against lipopolysaccharide by inhibiting autophagy. , 2014, Molecular medicine reports.

[34]  Saizhu Wu,et al.  Retarding the senescence of human vascular endothelial cells induced by hydrogen peroxide: effects of 17beta-estradiol (E2) mediated mitochondria protection , 2014, Biogerontology.

[35]  H. J. Yoo,et al.  Adipokines as a novel link between obesity and atherosclerosis. , 2014, World journal of diabetes.

[36]  S. Miyamoto,et al.  Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition. , 2014, Molecular cell.

[37]  Sung Hoon Kim,et al.  Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions , 2013, Proceedings of the National Academy of Sciences.

[38]  Ke Chen,et al.  Estradiol inhibits osteoblast apoptosis via promotion of autophagy through the ER–ERK–mTOR pathway , 2013, Apoptosis.

[39]  Gene Kim,et al.  The role of redox signaling in epigenetics and cardiovascular disease. , 2013, Antioxidants & redox signaling.

[40]  S. Catalano,et al.  Estrogen receptor beta (ERβ) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene , 2012, Cell cycle.

[41]  L. Al-Nakkash.  Genistein Stimulates Jejunal Chloride Secretion via Sex-dependent, Estrogen Receptor or Adenylate Cyclase Mechanisms , 2012, Cellular Physiology and Biochemistry.

[42]  T. Wakefield,et al.  Aging is associated with impaired thrombus resolution in a mouse model of stasis induced thrombosis. , 2010, Thrombosis research.

[43]  S. Beske,et al.  Nuclear Factor-&kgr;B Activation Contributes to Vascular Endothelial Dysfunction via Oxidative Stress in Overweight/Obese Middle-Aged and Older Humans , 2009, Circulation.

[44]  Keiji Tanaka,et al.  Selective turnover of p62/A170/SQSTM1 by autophagy , 2008, Autophagy.

[45]  Yongqiang Chen,et al.  Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells , 2008, Cell Death and Differentiation.

[46]  U. Çakatay,et al.  Male rats exhibit higher oxidative protein damage than females of the same chronological age , 2007, Mechanisms of Ageing and Development.

[47]  Saizhu Wu,et al.  Research on the Age-Related Changes in the Nitric Oxide Pathway in the Arteries of Rats and the Intervention Effect of Dehydroepiandrosterone , 2007, Gerontology.

[48]  T. H. Schiebler,et al.  The effect of sex hormones on the proximal tubules in the rat kidney , 1978, Cell and Tissue Research.

[49]  U. Çakatay,et al.  Postmenopausal Hormone Replacement Therapy Use Decreases Oxidative Protein Damage , 2003, Gynecologic and Obstetric Investigation.

[50]  J. Gustafsson,et al.  Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β , 2002, Science.

[51]  S. Yusuf,et al.  Risk factors, atherosclerosis, and cardiovascular disease among Aboriginal people in Canada: the Study of Health Assessment and Risk Evaluation in Aboriginal Peoples (SHARE-AP) , 2001, The Lancet.

[52]  M. Kindy,et al.  Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury , 2001 .

[53]  P. Chambon,et al.  Estradiol Accelerates Reendothelialization in Mouse Carotid Artery Through Estrogen Receptor-α but Not Estrogen Receptor-β , 2001 .

[54]  Takeshi Noda,et al.  LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing , 2000, The EMBO journal.

[55]  U. Çakatay,et al.  EFFECTS OF HORMONE REPLACEMENT THERAPY ON LIPID PEROXIDES AND OXIDATION SYSTEM IN POSTMENOPAUSAL WOMEN , 2000, Journal of toxicology and environmental health. Part A.

[56]  E. Vittinghoff,et al.  Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. , 1998, JAMA.

[57]  G. Stein,et al.  Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts. , 1990, Science.