论文信息 - An efficient preparation of the potent and selective pseudopeptide thrombin inhibitor, inogatran - 字舞流文

An efficient preparation of the potent and selective pseudopeptide thrombin inhibitor, inogatran

A. Doherty | W. L. Cody | M. A. Siddiqui | J. He | P. Préville | M. Tarazi

[1] L. Rydén,et al. Antithrombotic activity of inogatran, a new low-molecular-weight inhibitor of thrombin, in a closed-chest porcine model of coronary artery thrombosis. , 1996, Cardiovascular research.

[2] W. Nichols,et al. Inogatran, a novel direct low molecular weight thrombin inhibitor, given with, but not after, tissue-plasminogen activator, improves thrombolysis. , 1996, The Journal of pharmacology and experimental therapeutics.

[3] D. Gustafsson,et al. Effects of inogatran, a new low‐molecular‐weight thrombin inhibitor, in rat models of venous and arterial thrombosis, thrombolysis and bleeding time , 1996, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

[4] W. Nichols,et al. Aspirin does not potentiate effect of suboptimal dose of the thrombin inhibitor inogatran during coronary thrombolysis. , 1995, Cardiovascular research.

[5] C. Ehrhardt,et al. Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profile. , 1993, Trends in pharmacological sciences.

[6] J. Maraganore,et al. Thrombin-specific inhibition by and slow cleavage of hirulog-1. , 1992, The Biochemical journal.

[7] A. Barrett,et al. Redox glycosidation: stereoselective syntheses of (1.fwdarw.6) linked disaccharides via thionoester intermediates , 1992 .

[8] E. Shaw,et al. D-Phe-Pro-ArgCH2C1-A selective affinity label for thrombin. , 1979, Thrombosis research.