The oncogenic effects of HES1 on salivary adenoid cystic carcinoma cell growth and metastasis

[1]  L. Bolondi,et al.  Targeting Notch3 in Hepatocellular Carcinoma: Molecular Mechanisms and Therapeutic Perspectives , 2016, International journal of molecular sciences.

[2]  A. Rani,et al.  HES1 in immunity and cancer. , 2016, Cytokine & growth factor reviews.

[3]  J. James,et al.  Hes1: the maestro in neurogenesis , 2016, Cellular and Molecular Life Sciences.

[4]  A. Kinghorn,et al.  Silvestrol induces early autophagy and apoptosis in human melanoma cells , 2016, BMC Cancer.

[5]  Hl Lin,et al.  Hes1 Increases the Invasion Ability of Colorectal Cancer Cells via the STAT3-MMP14 Pathway , 2015, PloS one.

[6]  P. Bradley,et al.  Adenoid cystic carcinoma of the head and neck--An update. , 2015, Oral oncology.

[7]  Shiying Yu,et al.  Expression of Notch1 Correlates with Breast Cancer Progression and Prognosis , 2015, PloS one.

[8]  Yong Yu,et al.  HES1 activation suppresses proliferation of leukemia cells in acute myeloid leukemia , 2015, Annals of Hematology.

[9]  R. Langer,et al.  Clinical Significance of NOTCH1 and NOTCH2 Expression in Gastric Carcinomas: An Immunohistochemical Study , 2015, Front. Oncol..

[10]  H. Maehr,et al.  HES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44+/CD24−/low tumor-initiating subpopulation in basal-like breast cancer , 2015, The Journal of Steroid Biochemistry and Molecular Biology.

[11]  J. Xie,et al.  NOTCH1 signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinoma , 2014, Oncotarget.

[12]  F. Persson,et al.  Diagnostic and therapeutic implications of new molecular biomarkers in salivary gland cancers. , 2014, Oral oncology.

[13]  J. Sage,et al.  From fly wings to targeted cancer therapies: a centennial for notch signaling. , 2014, Cancer cell.

[14]  D. Xiao,et al.  Hes1 is involved in the self-renewal and tumourigenicity of stem-like cancer cells in colon cancer , 2014, Scientific Reports.

[15]  C. Moskaluk,et al.  TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior , 2013, Oncogene.

[16]  M. Prasad,et al.  Diagnostic SOX10 gene signatures in salivary adenoid cystic and breast basal-like carcinomas , 2013, British Journal of Cancer.

[17]  Kai Yang,et al.  Expression of integrin-linked kinase in adenoid cystic carcinoma of salivary glands correlates with epithelial–mesenchymal transition markers and tumor progression , 2013, Medical Oncology.

[18]  Z. Shang,et al.  EphA2/ephrinA1 mRNA expression and protein production in adenoid cystic carcinoma of salivary gland. , 2013, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[19]  T. Saku,et al.  Podoplanin is a novel myoepithelial cell marker in pleomorphic adenoma and other salivary gland tumors with myoepithelial differentiation , 2013, Virchows Archiv.

[20]  N. Park,et al.  TNFα enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells. , 2012, Biochemical and biophysical research communications.

[21]  C. Godballe,et al.  Prognostic significance of Ki-67 in salivary gland carcinomas. , 2012, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[22]  J. Aster,et al.  Targeting the Notch pathway: twists and turns on the road to rational therapeutics. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  D. Tuveson,et al.  Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice. , 2011, The Journal of clinical investigation.

[24]  Philip R. Cohen,et al.  Salivary duct carcinoma: targeting the phosphatidylinositol 3-kinase pathway by blocking mammalian target of rapamycin with temsirolimus. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[25]  Fazlul H. Sarkar,et al.  Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins? , 2011, Cancers.

[26]  L. Wilson,et al.  Determinants and Patterns of Survival in Adenoid Cystic Carcinoma of the Head and Neck, Including an Analysis of Adjuvant Radiation Therapy , 2011, American journal of clinical oncology.

[27]  R. Kageyama,et al.  Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity , 2009, The Journal of cell biology.

[28]  James M. Roberts,et al.  Control of the Reversibility of Cellular Quiescence by the Transcriptional Repressor HES1 , 2008, Science.

[29]  T. Ohtsuka,et al.  Roles of Hes genes in neural development , 2008, Development, growth & differentiation.

[30]  K. McCue,et al.  Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling , 2008, Oncogene.

[31]  Ryoichiro Kageyama,et al.  The Hes gene family: repressors and oscillators that orchestrate embryogenesis , 2007, Development.

[32]  L. L. Reed,et al.  Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells , 2006, Laboratory Investigation.

[33]  H. Axelson,et al.  Regulation of the Notch target gene Hes-1 by TGFalpha induced Ras/MAPK signaling in human neuroblastoma cells. , 2005, Experimental cell research.

[34]  J. Seol,et al.  The conserved WRPW motif of Hes6 mediates proteasomal degradation. , 2005, Biochemical and biophysical research communications.

[35]  Ryoichiro Kageyama,et al.  Roles of bHLH genes in neural stem cell differentiation. , 2005, Experimental cell research.

[36]  E. Bellefroid,et al.  Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners. , 2004, Developmental biology.

[37]  A. Eckardt,et al.  Adenoid cystic carcinoma of the head and neck--a 20 years experience. , 2004, International journal of oral and maxillofacial surgery.

[38]  Andrew I Su,et al.  Large scale molecular analysis identifies genes with altered expression in salivary adenoid cystic carcinoma. , 2002, The American journal of pathology.

[39]  H. Okano,et al.  Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling. , 2002, Development.

[40]  Alfred L. Fisher,et al.  The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain , 1996, Molecular and cellular biology.

[41]  Roger Brent,et al.  Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins , 1994, Cell.

[42]  K. Moriyoshi,et al.  Persistent expression of helix‐loop‐helix factor HES‐1 prevents mammalian neural differentiation in the central nervous system. , 1994, The EMBO journal.

[43]  A. Jimeno,et al.  A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer , 2016, International journal of cancer.

[44]  V. Deshpande,et al.  Heterogeneity in signaling pathways of gastroenteropancreatic neuroendocrine tumors: a critical look at notch signaling pathway , 2013, Modern Pathology.

[45]  James M. Roberts,et al.  Hijacking HES1: how tumors co-opt the anti-differentiation strategies of quiescent cells. , 2010, Trends in molecular medicine.

[46]  James S. Brown,et al.  15 – Prognostic Factors in Oral, Oropharyngeal, and Salivary Gland Cancer , 2006 .

[47]  S. Artavanis-Tsakonas,et al.  Notch signals control the fate of immature progenitor cells in the intestine. , 2005, Nature Reviews Molecular Cell Biology.

[48]  J. Massagué Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway , 2005 .

[49]  Ryoichiro Kageyama,et al.  Control of endodermal endocrine development by Hes-1 , 2000, Nature Genetics.