Therapeutic effect of autologous bone grafting with adjuvant bone morphogenetic protein on long bone nonunion: a systematic review and meta-analysis

[1]  E. Mayo-Wilson,et al.  The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. , 2021, Journal of clinical epidemiology.

[2]  E. Mayo-Wilson,et al.  The PRISMA 2020 statement: an updated guideline for reporting systematic reviews , 2020, BMJ.

[3]  M. Gardner,et al.  Bone marrow aspirate concentrate with cancellous allograft versus iliac crest bone graft in the treatment of long bone nonunions , 2019, OTA international : the open access journal of orthopaedic trauma.

[4]  G. Schmidmaier,et al.  Comparison of the clinical effectiveness of Bone Morphogenic Protein (BMP) -2 and -7 in the adjunct treatment of lower limb nonunions. , 2018, Orthopaedics & traumatology, surgery & research : OTSR.

[5]  J. Friederichs,et al.  Long-term outcome following additional rhBMP-7 application in revision surgery of aseptic humeral, femoral, and tibial shaft nonunion , 2017, BMC Musculoskeletal Disorders.

[6]  Gopal Shankar Krishnakumar,et al.  Clinical application of bone morphogenetic proteins for bone healing: a systematic review , 2017, International Orthopaedics.

[7]  S. Manochantr,et al.  Bone morphogenetic protein-2 enhances the osteogenic differentiation capacity of mesenchymal stromal cells derived from human bone marrow and umbilical cord , 2017, International journal of molecular medicine.

[8]  P. Augat,et al.  Comparative study suggests that human bone morphogenetic proteins have no influence on the outcome of operative treatment of aseptic clavicle non-unions , 2016, International Orthopaedics.

[9]  J. Friederichs,et al.  The missing effect of human recombinant Bone Morphogenetic Proteins BMP-2 and BMP-7 in surgical treatment of aseptic forearm nonunion. , 2016, Injury.

[10]  I. Ban,et al.  Risk profile of patients developing nonunion of the clavicle and outcome of treatment—analysis of fifty five nonunions in seven hundred and twenty nine consecutive fractures , 2016, International Orthopaedics.

[11]  A. Moghaddam,et al.  [Long Bone Nonunion]. , 2015, Zeitschrift fur Orthopadie und Unfallchirurgie.

[12]  Y. Chai,et al.  Bone Morphogenetic Protein for the Healing of Tibial Fracture: A Meta-Analysis of Randomized Controlled Trials , 2015, PloS one.

[13]  A. Oryan,et al.  Bone morphogenetic proteins: A powerful osteoinductive compound with non‐negligible side effects and limitations , 2014, BioFactors.

[14]  K. Egol,et al.  No advantage to rhBMP-2 in addition to autogenous graft for fracture nonunion. , 2014, Orthopedics.

[15]  M. Bhandari,et al.  Efficacy and safety of recombinant human bone morphogenetic protein-2/calcium phosphate matrix for closed tibial diaphyseal fracture: a double-blind, randomized, controlled phase-II/III trial. , 2013, The Journal of bone and joint surgery. American volume.

[16]  R. Capanna,et al.  Cost effectiveness of tibial nonunion treatment: A comparison between rhBMP-7 and autologous bone graft in two Italian centres. , 2013, Injury.

[17]  C. Wölfl,et al.  Ergebnisse der Pseudarthrosenbehandlung mit „bone morphogenetic protein 7“ (BMP-7) , 2012, Der Unfallchirurg.

[18]  W. Obremskey,et al.  Bone morphogenetic protein-2 compared to autologous iliac crest bone graft in the treatment of long bone nonunion. , 2011, Orthopedics.

[19]  P. Giannoudis,et al.  Complications following autologous bone graft harvesting from the iliac crest and using the RIA: a systematic review. , 2011, Injury.

[20]  A. Stang.  Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses , 2010, European Journal of Epidemiology.

[21]  Ian Harvey,et al.  Bone morphogenetic protein (BMP) for fracture healing in adults. , 2010, The Cochrane database of systematic reviews.

[22]  P. Giannoudis,et al.  A cost analysis of treatment of tibial fracture nonunion by bone grafting or bone morphogenetic protein-7 , 2009, International Orthopaedics.

[23]  M. Harris,et al.  Recent developments in the biology of fracture repair. , 2008, The Journal of the American Academy of Orthopaedic Surgeons.

[24]  P. Giannoudis,et al.  Fracture healing: the diamond concept. , 2007, Injury.

[25]  T. Miclau,et al.  Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions? , 2007, Injury.

[26]  S. Santavirta,et al.  Recombinant Human Bone Morphogenetic Protein-2 for Treatment of Open Tibial Fractures: A Prospective, Controlled, Randomized Study of Four Hundred and Fifty Patients , 2002, The Journal of bone and joint surgery. American volume.

[27]  G. Zych,et al.  Osteogenic Protein-1 (Bone Morphogenetic Protein-7) in the Treatment of Tibial Nonunions: A Prospective, Randomized Clinical Trial Comparing rhOP-1 with Fresh Bone Autograft* , 2001, The Journal of bone and joint surgery. American volume.

[28]  S. Cook.  Preclinical and clinical evaluation of osteogenic protein-1 (BMP-7) in bony sites. , 1999, Orthopedics.

[29]  B. Biglari,et al.  [Results of nonunion treatment with bone morphogenetic protein 7 (BMP-7)]. , 2012, Der Unfallchirurg.