Repression of the expression of proinflammatory genes by mitochondrial transcription factor A is linked to its alternative splicing regulation in human lung epithelial cells

[1]  M. Li,et al.  Linking endotypes to omics profiles in difficult-to-control asthma using the diagnostic Chinese medicine syndrome differentiation algorithm , 2020, The Journal of asthma : official journal of the Association for the Care of Asthma.

[2]  Li-Jen Lin,et al.  DFSG, a novel herbal cocktail with anti-asthma activity, suppressed MUC5AC in A549 cells and alleviated allergic airway hypersensitivity and inflammatory cell infiltration in a chronic asthma mouse model. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[3]  Jiakun Shen,et al.  The roles of Nrf2 and autophagy in modulating inflammation mediated by TLR4 - NFκB in A549 cell exposed to layer house particulate matter 2.5 (PM2.5). , 2019, Chemosphere.

[4]  Jie Xie,et al.  RBM4 modulates the proliferation and expression of inflammatory factors via the alternative splicing of regulatory factors in HeLa cells , 2019, Molecular Genetics and Genomics.

[5]  Yaxun Wei,et al.  CRKL regulates alternative splicing of cancer-related genes in cervical cancer samples and HeLa cell , 2019, BMC Cancer.

[6]  A. Dixon,et al.  Diet and Metabolism in the Evolution of Asthma and Obesity. , 2019, Clinics in chest medicine.

[7]  D. Mishmar,et al.  Mitochondrial DNA Transcription and Its Regulation: An Evolutionary Perspective. , 2018, Trends in genetics : TIG.

[8]  M. Pajares,et al.  Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels , 2018, Human mutation.

[9]  A. Hevener,et al.  New mitochondrial DNA synthesis enables NLRP3 inflammasome activation , 2018, Nature.

[10]  B. Kaufman,et al.  The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms , 2018, FEBS letters.

[11]  Gang Wu,et al.  CELF1 preferentially binds to exon-intron boundary and regulates alternative splicing in HeLa cells. , 2017, Biochimica et biophysica acta. Gene regulatory mechanisms.

[12]  A. West,et al.  Mitochondrial DNA in innate immune responses and inflammatory pathology , 2017, Nature Reviews Immunology.

[13]  B. Behnam,et al.  A rare case of Sjogren-Larsson syndrome with recurrent pneumonia and asthma , 2016, Korean journal of pediatrics.

[14]  R. Marthan,et al.  Selective dysfunction of p53 for mitochondrial biogenesis induces cellular proliferation in bronchial smooth muscle from asthmatic patients. , 2016, The Journal of allergy and clinical immunology.

[15]  V. Pascual,et al.  Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus , 2016, The Journal of experimental medicine.

[16]  V. Hornung,et al.  Recognition of Endogenous Nucleic Acids by the Innate Immune System. , 2016, Immunity.

[17]  Yue-ying Gu,et al.  Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof‐of‐Concept Trial of Metformin , 2015, Arthritis & rheumatology.

[18]  R. Means,et al.  Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response , 2014, Nature.

[19]  B. Ryffel,et al.  The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells , 2014, Nature Immunology.

[20]  C. Ballard,et al.  Association of a polymorphism in mitochondrial transcription factor A (TFAM) with Parkinson's disease dementia but not dementia with Lewy bodies , 2013, Neuroscience Letters.

[21]  Jeroen Krijgsveld,et al.  The RNA-binding protein repertoire of embryonic stem cells , 2013, Nature Structural &Molecular Biology.

[22]  K. Tracey,et al.  The many faces of HMGB1: molecular structure‐functional activity in inflammation, apoptosis, and chemotaxis , 2013, Journal of leukocyte biology.

[23]  Cole Trapnell,et al.  TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions , 2013, Genome Biology.

[24]  J. Kolesar,et al.  Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number. , 2012, Biochimica et biophysica acta.

[25]  E. Crouser,et al.  Mitochondrial Transcription Factor A Serves as a Danger Signal by Augmenting Plasmacytoid Dendritic Cell Responses to DNA , 2012, The Journal of Immunology.

[26]  Richard Bonneau,et al.  The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. , 2012, Molecular cell.

[27]  Norman E. Davey,et al.  Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins , 2012, Cell.

[28]  S. Holgate Innate and adaptive immune responses in asthma , 2012, Nature Medicine.

[29]  S. Erzurum,et al.  Nitric oxide metabolism in asthma pathophysiology. , 2011, Biochimica et biophysica acta.

[30]  Chuan-Yun Li,et al.  KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases , 2011, Nucleic Acids Res..

[31]  K. Hardy,et al.  Arginase and Arginine Dysregulation in Asthma , 2011, Journal of allergy.

[32]  Wei Yang,et al.  A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression , 2011, Respiratory research.

[33]  H. Kettenmann,et al.  Physiology of microglia. , 2011, Physiological reviews.

[34]  L. Tan,et al.  Mitochondrial transcription factor A (TFAM) polymorphisms and risk of late-onset Alzheimer's disease in Han Chinese , 2011, Brain Research.

[35]  R. Marthan,et al.  Pathophysiology of bronchial smooth muscle remodelling in asthma , 2010, European Respiratory Journal.

[36]  C. Glass,et al.  Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. , 2010, Molecular cell.

[37]  Cole Trapnell,et al.  Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. , 2010, Nature biotechnology.

[38]  Davis J. McCarthy,et al.  edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..

[39]  C. Lemière,et al.  Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction. , 2009, The Journal of allergy and clinical immunology.

[40]  J. Hsu,et al.  Asthma Drugs Counter-regulate interleukin-8 Release Stimulated by Sodium Sulfite in an A549 Cell Line , 2009, The Journal of asthma : official journal of the Association for the Care of Asthma.

[41]  Y. Li,et al.  The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. , 2008, Immunity.

[42]  J. Vernejoux,et al.  Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma , 2007, The Journal of experimental medicine.

[43]  Santiago Costantino,et al.  The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures. , 2007, Molecular biology of the cell.

[44]  Marc R. Blackman,et al.  Mitochondria as key components of the stress response , 2007, Trends in Endocrinology & Metabolism.

[45]  N. Hamasaki,et al.  Human mitochondrial DNA is packaged with TFAM. , 2003, Nucleic acids research.

[46]  M. Tamm,et al.  Airway smooth muscle cell proliferation is increased in asthma. , 2001, American journal of respiratory and critical care medicine.

[47]  L. Kobzik,et al.  Environmental particulate-mediated cytokine production in lung epithelial cells (A549): role of preexisting inflammation and oxidant stress. , 1998, Journal of toxicology and environmental health. Part A.

[48]  T. Mak,et al.  Involvement of the IRF-1 transcription factor in antiviral responses to interferons. , 1994, Science.

[49]  K. Elkon,et al.  Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease , 2015, Nature Medicine.