Advances in genomic characterization of circulating tumor cells

[1]  A. Voigt,et al.  Immune escape and survival mechanisms in circulating tumor cells of colorectal cancer. , 2014, Cancer research.

[2]  X. Xie,et al.  Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients , 2013, Proceedings of the National Academy of Sciences.

[3]  John W. Park,et al.  Isolation of circulating tumor cells by immunomagnetic enrichment and fluorescence-activated cell sorting (IE/FACS) for molecular profiling. , 2013, Methods.

[4]  Klaus Pantel,et al.  Tumor metastasis: moving new biological insights into the clinic , 2013, Nature Medicine.

[5]  Z. Werb,et al.  Circulating Tumor Cells , 2013, Science.

[6]  I. Thompson,et al.  Single‐cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT‐related genes in metastatic prostate cancer , 2013, The Prostate.

[7]  Peter Ulz,et al.  Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing. , 2013, Cancer research.

[8]  Tim Holland-Letz,et al.  Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay , 2013, Nature Biotechnology.

[9]  Mehmet Toner,et al.  Inertial Focusing for Tumor Antigen–Dependent and –Independent Sorting of Rare Circulating Tumor Cells , 2013, Science Translational Medicine.

[10]  Massimo Cristofanilli,et al.  Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition , 2013 .

[11]  Adam Olshen,et al.  Genomic profiling of isolated circulating tumor cells from metastatic breast cancer patients. , 2013, Cancer research.

[12]  Klaus Pantel,et al.  Circulating tumor cells: liquid biopsy of cancer. , 2013, Clinical chemistry.

[13]  X. Xie,et al.  Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell , 2012, Science.

[14]  M. Ronaghi,et al.  mRNA-Seq of Single Prostate Cancer Circulating Tumor Cells Reveals Recapitulation of Gene Expression and Pathways Found in Prostate Cancer , 2012, PloS one.

[15]  Sridhar Ramaswamy,et al.  Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer. , 2012, Cancer discovery.

[16]  Ben S. Wittner,et al.  Corrigendum: RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis , 2012, Nature.

[17]  Sabine Riethdorf,et al.  High‐resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer , 2012, International journal of cancer.

[18]  Daniel MacArthur,et al.  Methods: Face up to false positives , 2012, Nature.

[19]  Rafael López-López,et al.  Molecular Characterization of Circulating Tumor Cells in Human Metastatic Colorectal Cancer , 2012, PloS one.

[20]  R. Sandberg,et al.  Full-Length mRNA-Seq from single cell levels of RNA and individual circulating tumor cells , 2012, Nature Biotechnology.

[21]  S. Jeffrey,et al.  Multiplex molecular analysis of CTCs. , 2012, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

[22]  Gyan Bhanot,et al.  Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines , 2012, PloS one.

[23]  Kevin A. Pelphrey,et al.  Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell , 2012 .

[24]  M. Roizen,et al.  Hallmarks of Cancer: The Next Generation , 2012 .

[25]  D. Pinkel,et al.  Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer , 2012, BMC Cancer.

[26]  S. Kurtz,et al.  Quantitative High-Resolution Genomic Analysis of Single Cancer Cells , 2011, PloS one.

[27]  K. Pantel,et al.  Clinical relevance and biology of circulating tumor cells , 2011, Breast Cancer Research.

[28]  Howard I. Scher,et al.  Circulating Tumor Cells as Biomarkers in Prostate Cancer , 2011, Clinical Cancer Research.

[29]  John W M Martens,et al.  mRNA and microRNA Expression Profiles in Circulating Tumor Cells and Primary Tumors of Metastatic Breast Cancer Patients , 2011, Clinical Cancer Research.

[30]  P. Jänne,et al.  A new device for rapid isolation by size and characterization of rare circulating tumor cells. , 2011, Anticancer research.

[31]  John W. Park.  Disseminated tumor cells: the method is the message , 2011, Breast Cancer Research and Treatment.

[32]  K. Isselbacher,et al.  Isolation of circulating tumor cells using a microvortex-generating herringbone-chip , 2010, Proceedings of the National Academy of Sciences.

[33]  S. Bodovitz,et al.  Single cell analysis: the new frontier in 'omics'. , 2010, Trends in biotechnology.

[34]  M. Golightly,et al.  Isolation of circulating epithelial and tumor progenitor cells with an invasive phenotype from breast cancer patients , 2010, International journal of cancer.

[35]  Larry Norton,et al.  Tumor Self-Seeding by Circulating Cancer Cells , 2009, Cell.

[36]  S. Tan,et al.  DNA, RNA, and Protein Extraction: The Past and The Present , 2009, Journal of biomedicine & biotechnology.

[37]  C. Punt,et al.  Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer. , 2009, Annals of oncology : official journal of the European Society for Medical Oncology.

[38]  Kenneth J. Pienta,et al.  Circulating Tumor Cells Predict Survival Benefit From Treatment in Metastatic Castration-Resistant Prostate Cancer Editorial Comment , 2009 .

[39]  Emmanuel R. Yera,et al.  Functional phenotyping and genotyping of circulating tumor cells from patients with castration resistant prostate cancer. , 2009, Cancer letters.

[40]  T. Ragg,et al.  Perioperative activation of disseminated tumor cells in bone marrow of patients with prostate cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[41]  C. Klein,et al.  Parallel progression of primary tumours and metastases , 2009, Nature Reviews Cancer.

[42]  Mark M Davis,et al.  Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device , 2009, Proceedings of the National Academy of Sciences.

[43]  Mieke Schutte,et al.  Anti-Epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-Like Breast Tumor Cells , 2009, Journal of the National Cancer Institute.

[44]  L. Terstappen,et al.  Commentary the molecular characterization of 19 breast cancer cell lines by Sieuwerts et al. , 2009 .

[45]  Yixin Wang,et al.  Re: Anti-epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells. , 2009, Journal of the National Cancer Institute.

[46]  John A. Foekens,et al.  Molecular characterization of circulating tumor cells in large quantities of contaminating leukocytes by a multiplex real-time PCR , 2009, Breast Cancer Research and Treatment.

[47]  K. Pienta,et al.  Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer , 2008, Clinical Cancer Research.

[48]  B. Trask,et al.  Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients. , 2008, Cancer research.

[49]  Michael Morse,et al.  Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[50]  Ruud H. Brakenhoff,et al.  Detection, clinical relevance and specific biological properties of disseminating tumour cells , 2008, Nature Reviews Cancer.

[51]  R. Reinhardt,et al.  High-resolution array comparative genomic hybridization of single micrometastatic tumor cells , 2008, Nucleic acids research.

[52]  Y. Wong,et al.  Decreased adhesiveness, resistance to anoikis and suppression of GRP94 are integral to the survival of circulating tumor cells in prostate cancer , 2008, Clinical & Experimental Metastasis.

[53]  L. Zhao,et al.  Simultaneous isolation of DNA and RNA from the same cell population obtained by laser capture microdissection for genome and transcriptome profiling. , 2008, The Journal of molecular diagnostics : JMD.

[54]  S. Digumarthy,et al.  Isolation of rare circulating tumour cells in cancer patients by microchip technology , 2007, Nature.

[55]  Kenneth M. Yamada,et al.  Modeling Tissue Morphogenesis and Cancer in 3D , 2007, Cell.

[56]  J. Nesland,et al.  Comparison of the clinical significance of occult tumor cells in blood and bone marrow in breast cancer , 2006, International journal of cancer.

[57]  R. Eils,et al.  Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer. , 2005, Cancer cell.

[58]  K. Pienta,et al.  Global gene expression profiling of circulating tumor cells. , 2005, Cancer research.

[59]  Thomas Rau,et al.  Circulating Tumor Cells in Breast Cancer: Correlation to Bone Marrow Micrometastases, Heterogeneous Response to Systemic Therapy and Low Proliferative Activity , 2005, Clinical Cancer Research.

[60]  Alison Stopeck,et al.  Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[61]  Jonathan W. Uhr,et al.  Tumor Cells Circulate in the Peripheral Blood of All Major Carcinomas but not in Healthy Subjects or Patients With Nonmalignant Diseases , 2004, Clinical Cancer Research.

[62]  Alison Stopeck,et al.  Circulating tumor cells, disease progression, and survival in metastatic breast cancer. , 2004, The New England journal of medicine.

[63]  L. Terstappen,et al.  Multigene reverse transcription-PCR profiling of circulating tumor cells in hormone-refractory prostate cancer. , 2004, Clinical chemistry.

[64]  Anne Vincent-Salomon,et al.  Clinical Significance of Immunocytochemical Detection of Tumor Cells Using Digital Microscopy in Peripheral Blood and Bone Marrow of Breast Cancer Patients , 2004, Clinical Cancer Research.

[65]  G. Rassner,et al.  Immunomagnetic Enrichment, Genomic Characterization, and Prognostic Impact of Circulating Melanoma Cells , 2004, Clinical Cancer Research.

[66]  Joe W Gray,et al.  Evidence emerges for early metastasis and parallel evolution of primary and metastatic tumors. , 2003, Cancer cell.

[67]  R. Eils,et al.  From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[68]  Christopher W. Wong,et al.  Apoptosis: an early event in metastatic inefficiency. , 2001, Cancer research.

[69]  G. Naumov,et al.  Molecular biology of breast cancer metastasis: Clinical implications of experimental studies on metastatic inefficiency , 2000, Breast Cancer Research.

[70]  I. Macdonald,et al.  Temporal progression of metastasis in lung: cell survival, dormancy, and location dependence of metastatic inefficiency. , 2000, Cancer research.

[71]  M. Speicher,et al.  Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[72]  W. Kuo,et al.  High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays , 1998, Nature Genetics.

[73]  Jorma Isola,et al.  In vivo amplification of the androgen receptor gene and progression of human prostate cancer , 1995, Nature Genetics.

[74]  S. Hirohashi,et al.  E-cadherin is the major mediator of human melanocyte adhesion to keratinocytes in vitro. , 1994, Journal of cell science.