Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in the radiotherapy of advanced head and neck cancers: results of the EORTC 22851 randomized trial.

[1]  G. Steel,et al.  Basic Clinical Radiobiology , 1997 .

[2]  M. I. Saunders,et al.  Randomised multicentre trials of CHART vs conventional radiotherapy in head and neck and non-small-cell lung cancer: an interim report. CHART Steering Committee. , 1996, British Journal of Cancer.

[3]  J. Horiot,et al.  The EORTC randomized trial on three fractions per day and misonidazole (trial no. 22811) in advanced head and neck cancer: long-term results and side effects. , 1995, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[4]  J. Horiot,et al.  The EORTC randomized trial on three fractions per day and misonidazole in advanced head and neck cancer: prognostic factors. , 1995, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[5]  Jacques Bernier,et al.  Late effects toxicity scoring: the SOMA scale , 1995 .

[6]  S Schraub,et al.  Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a randomized trial of the EORTC cooperative group of radiotherapy. , 1992, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[7]  M. Lindstrom,et al.  Re-analysis of the time factor in local control by radiotherapy of T3T4 squamous cell carcinoma of the larynx. , 1991, International journal of radiation oncology, biology, physics.

[8]  H. Bartelink,et al.  The predictive value of cell kinetic measurements in a European trial of accelerated fractionation in advanced head and neck tumors: an interim report. , 1990, International journal of radiation oncology, biology, physics.

[9]  J. Fowler,et al.  Further analysis of the time factor in squamous cell carcinoma of the tonsillar region. , 1990, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[10]  Alan Horwich,et al.  The Biological Basis of Radiotherapy , 1989 .

[11]  H. Bartelink,et al.  European Organization for Research on Treatment of Cancer trials using radiotherapy with multiple fractions per day. A 1978-1987 survey. , 1988, Frontiers of radiation therapy and oncology.

[12]  C. C. Wang,et al.  Local control of oropharyngeal carcinoma after two accelerated hyperfractionation radiation therapy schemes. , 1988, International journal of radiation oncology, biology, physics.

[13]  D. Shrieve,et al.  A method to measure the duration of DNA synthesis and the potential doubling time from a single sample. , 1985, Cytometry.

[14]  J. Horiot,et al.  Late results of multiple fractions per day (MFD) with misonidazole in advanced cancer of the head and neck. A pilot study of the EORTC radiotherapy group. , 1985, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[15]  G. Barendsen,et al.  Dose fractionation, dose rate and iso-effect relationships for normal tissue responses. , 1982, International journal of radiation oncology, biology, physics.

[16]  K. Trott,et al.  The influence of the number of fractions and of overall treatment time on local control and late complication rate in squamous cell carcinoma of the larynx. , 1981, International journal of radiation oncology, biology, physics.

[17]  F. Bova,et al.  A re-evaluation of split-course technique for squamous cell carcinoma of the head and neck. , 1980, International journal of radiation oncology, biology, physics.

[18]  S. Pocock,et al.  Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. , 1975, Biometrics.

[19]  N. Mantel.  Evaluation of survival data and two new rank order statistics arising in its consideration. , 1966, Cancer chemotherapy reports.

[20]  E. Kaplan,et al.  Nonparametric Estimation from Incomplete Observations , 1958 .

[21]  Cai Grau,et al.  110Conventional radiotherapy as the primary treatment of squamous cell carcinoma (SCC) of the head and neck. A randomized multicenter study of 5 versus 6 fractions per week — Preliminary report from the Dahanca 6 and 7 trial , 1996 .

[22]  P. Warde,et al.  153 A prospective randomized trial of hyperfractionated versus conventional once daily radiation for advanced squamous cell carcinomas of the larynx and pharynx , 1996 .

[23]  M. Lindstrom,et al.  Loss of local control with prolongation in radiotherapy. , 1992, International journal of radiation oncology, biology, physics.

[24]  H. Withers,et al.  Innovations in Radiation Oncology , 1988, Medical Radiology.

[25]  L. Freedman.  Tables of the number of patients required in clinical trials using the logrank test. , 1982, Statistics in medicine.

[26]  J. Horiot,et al.  Clinical experience with multiple daily fractionation (MFD) in the radiotherapy of head and neck cancer , 1982 .

[27]  D. Cox.  Regression Models and Life-Tables , 1972 .