Lactic acid bacteria enhance autophagic ability of mononuclear phagocytes by increasing Th1 autophagy-promoting cytokine (IFN-gamma) and nitric oxide (NO) levels and reducing Th2 autophagy-restraining cytokines (IL-4 and IL-13) in response to Mycobacterium tuberculosis antigen.

[1]  M. Falagas,et al.  Probiotics for the prevention of respiratory tract infections: a systematic review. , 2009, International journal of antimicrobial agents.

[2]  C. Grangette,et al.  Differential crosstalk between epithelial cells, dendritic cells and bacteria in a co-culture model. , 2009, International journal of food microbiology.

[3]  J. Keane,et al.  Th1-Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages. , 2009, Veterinary immunology and immunopathology.

[4]  J. Pieters,et al.  Mycobacterial subversion of chemotherapeutic reagents and host defense tactics: challenges in tuberculosis drug development. , 2009, Annual review of pharmacology and toxicology.

[5]  L. Fabbri,et al.  Mycobacterium tuberculosis Induces CCL18 Expression in Human Macrophages , 2008, Scandinavian journal of immunology.

[6]  M. de Vrese,et al.  Effects of probiotic bacteria and their genomic DNA on TH1/TH2-cytokine production by peripheral blood mononuclear cells (PBMCs) of healthy and allergic subjects. , 2008, Immunobiology.

[7]  S. Jozefowski,et al.  How Mycobacterium tuberculosis subverts host immune responses , 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.

[8]  S. Jolles,et al.  Beneficial effect of anti-interleukin-4 antibody when administered in a murine model of tuberculosis infection. , 2008, Tuberculosis.

[9]  A. Heinzmann,et al.  Lactobacillus GG has in vitro effects on enhanced interleukin‐10 and interferon‐γ release of mononuclear cells but no in vivo effects in supplemented mothers and their neonates , 2008, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[10]  I. Iliev,et al.  Immunostimulatory Oligodeoxynucleotide Containing TTTCGTTT Motif from Lactobacillus rhamnosus GG DNA Potentially Suppresses OVA‐specific IgE Production in Mice , 2008, Scandinavian journal of immunology.

[11]  R. Kekkonen,et al.  Probiotic Leuconostoc mesenteroides ssp. cremoris and Streptococcus thermophilus induce IL-12 and IFN-gamma production. , 2008, World journal of gastroenterology.

[12]  Alimuddin Zumla,et al.  Ex Vivo Cytokine mRNA Levels Correlate with Changing Clinical Status of Ethiopian TB Patients and their Contacts Over Time , 2008, PloS one.

[13]  J. Keane,et al.  T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. , 2007, Immunity.

[14]  H. Smits,et al.  Selection of probiotic bacteria for prevention of allergic diseases: immunomodulation of neonatal dendritic cells , 2007, Clinical and experimental immunology.

[15]  T. Ghosh,et al.  TLR-TLR cross talk in human PBMC resulting in synergistic and antagonistic regulation of type-1 and 2 interferons, IL-12 and TNF-alpha. , 2007, International immunopharmacology.

[16]  A. Acharya,et al.  THIS ARTICLE HAS BEEN RETRACTED
Interleukin‐13‐induced type II polarization of inflammatory macrophages is mediated through suppression of nuclear factor‐κB and preservation of IκBα in a T cell lymphoma , 2007 .

[17]  D. Rubinsztein,et al.  Potential therapeutic applications of autophagy , 2007, Nature Reviews Drug Discovery.

[18]  M. Inman,et al.  Oral treatment with live Lactobacillus reuteri inhibits the allergic airway response in mice. , 2007, American journal of respiratory and critical care medicine.

[19]  D. Brassart,et al.  Correlation between in vitro and in vivo immunomodulatory properties of lactic acid bacteria. , 2007, World journal of gastroenterology.

[20]  I. Nakagawa,et al.  Autophagy in innate immunity against intracellular bacteria. , 2006, Journal of biochemistry.

[21]  B. Wallaert,et al.  Involvement of CCL18 in Allergic Asthma1 , 2006, The Journal of Immunology.

[22]  V. Deretic,et al.  Autophagy in Immune Defense Against Mycobacterium tuberculosis , 2006, Autophagy.

[23]  Alimuddin Zumla,et al.  The 6-Kilodalton Early Secreted Antigenic Target-Responsive, Asymptomatic Contacts of Tuberculosis Patients Express Elevated Levels of Interleukin-4 and Reduced Levels of Gamma Interferon , 2006, Infection and Immunity.

[24]  S. Prescott,et al.  Clinical effects of probiotics are associated with increased interferon‐γ responses in very young children with atopic dermatitis , 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[25]  J. Hampe,et al.  Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trial. , 2005, Clinical nutrition.

[26]  T. Hartung,et al.  Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[27]  M. Sata,et al.  Probiotic Lactobacillus‐induced improvement in murine chronic inflammatory bowel disease is associated with the down‐regulation of pro‐inflammatory cytokines in lamina propria mononuclear cells , 2005, Clinical and experimental immunology.

[28]  S. Prescott,et al.  Effects of probiotics on atopic dermatitis: a randomised controlled trial , 2005, Archives of Disease in Childhood.

[29]  Alimuddin Zumla,et al.  Do successful tuberculosis vaccines need to be immunoregulatory rather than merely Th1-boosting? , 2005, Vaccine.

[30]  V. Deretic,et al.  Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages , 2004, Cell.

[31]  M. Reed,et al.  Differential Monocyte Activation Underlies Strain-Specific Mycobacterium tuberculosis Pathogenesis , 2004, Infection and Immunity.

[32]  K. Dheda,et al.  IL-4 in tuberculosis: implications for vaccine design. , 2004, Trends in immunology.

[33]  Praveen Kumar,et al.  Mycobacterium tuberculosis induces high production of nitric oxide in coordination with production of tumour necrosis factor‐α in patients with fresh active tuberculosis but not in MDR tuberculosis , 2004, Immunology and cell biology.

[34]  R. Korpela,et al.  Lactobacillus GG effect in increasing IFN-gamma production in infants with cow's milk allergy. , 2004, The Journal of allergy and clinical immunology.

[35]  N. Boéchat,et al.  Down-Modulation of Lung Immune Responses by Interleukin-10 and Transforming Growth Factor β (TGF-β) and Analysis of TGF-β Receptors I and II in Active Tuberculosis , 2004, Infection and Immunity.

[36]  Hsiao-Chuan Lin,et al.  Treatment of perennial allergic rhinitis with lactic acid bacteria , 2004, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[37]  Jennifer Y. Zhang,et al.  Innate Inhibition of Adaptive Immunity: Mycobacterium tuberculosis-Induced IL-6 Inhibits Macrophage Responses to IFN-γ 1 , 2003, The Journal of Immunology.

[38]  Dirk Schnappinger,et al.  Inhibition of Respiration by Nitric Oxide Induces a Mycobacterium tuberculosis Dormancy Program , 2003, The Journal of experimental medicine.

[39]  S. Salminen,et al.  Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial , 2003, The Lancet.

[40]  K. Michaelsen,et al.  Effect of probiotic lactobacillus strains in children with atopic dermatitis , 2003, The Journal of allergy and clinical immunology.

[41]  Sarman Singh,et al.  Effect of Mycobacterium tuberculosis-Specific 10-Kilodalton Antigen on Macrophage Release of Tumor Necrosis Factor Alpha and Nitric Oxide , 2002, Infection and Immunity.

[42]  A. Mercenier,et al.  Lactic acid bacteria inhibit TH2 cytokine production by mononuclear cells from allergic patients. , 2002, The Journal of allergy and clinical immunology.

[43]  J. K. Park,et al.  Profiles of IFN‐γ and its regulatory cytokines (IL‐12, IL‐18 and IL‐10) in peripheral blood mononuclear cells from patients with multidrug‐resistant tuberculosis , 2002 .

[44]  B. Andersson,et al.  Gram-Positive Bacteria Are Potent Inducers of Monocytic Interleukin-12 (IL-12) while Gram-Negative Bacteria Preferentially Stimulate IL-10 Production , 2000, Infection and Immunity.

[45]  I. Julkunen,et al.  Lactobacilli and Streptococci Activate NF-κB and STAT Signaling Pathways in Human Macrophages1 , 2000, The Journal of Immunology.

[46]  G. Trinchieri,et al.  Inhibition of IL-12 Production in Human Monocyte-Derived Macrophages by TNF1 , 2000, The Journal of Immunology.

[47]  D. Golenbock,et al.  Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis. , 1999, Journal of immunology.

[48]  G. Rook,et al.  A sensitive, non-radioactive quantitative method for measuring IL-4 and IL-4delta2 mRNA in unstimulated cells from multiple clinical samples, using nested RT-PCR. , 1999, Journal of immunological methods.

[49]  S. Giosué,et al.  Cytokine levels correlate with a radiologic score in active pulmonary tuberculosis. , 1999, American journal of respiratory and critical care medicine.

[50]  M. Kurimoto,et al.  Lactobacilli and Streptococci Induce Interleukin-12 (IL-12), IL-18, and Gamma Interferon Production in Human Peripheral Blood Mononuclear Cells , 1998, Infection and Immunity.

[51]  J. Ho,et al.  Induction of in vitro human macrophage anti-Mycobacterium tuberculosis activity: requirement for IFN-gamma and primed lymphocytes. , 1998, Journal of immunology.

[52]  S. Hachimura,et al.  Lactobacillus casei Inhibits Antigen-Induced IgE Secretion through Regulation of Cytokine Production in Murine Splenocyte Cultures , 1998, International Archives of Allergy and Immunology.

[53]  M. Torres,et al.  Cytokine Profiles for Peripheral Blood Lymphocytes from Patients with Active Pulmonary Tuberculosis and Healthy Household Contacts in Response to the 30-Kilodalton Antigen ofMycobacterium tuberculosis , 1998, Infection and Immunity.

[54]  M. Burdick,et al.  Induction of gamma interferon production in human alveolar macrophages by Mycobacterium tuberculosis , 1997, Infection and immunity.

[55]  O. Kwon.  The role of nitric oxide in the immune response of tuberculosis. , 1997, Journal of Korean medical science.

[56]  J. Mudgett,et al.  Identification of nitric oxide synthase as a protective locus against tuberculosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[57]  G. Trinchieri,et al.  Cytokines acting on or secreted by macrophages during intracellular infection (IL-10, IL-12, IFN-gamma). , 1997, Current opinion in immunology.

[58]  E. Isolauri,et al.  Probiotics: a novel approach in the management of food allergy. , 1997, The Journal of allergy and clinical immunology.

[59]  G. Kaplan,et al.  Comparable growth of virulent and avirulent Mycobacterium tuberculosis in human macrophages in vitro. , 1996, The Journal of infectious diseases.

[60]  W. Boom,et al.  Interleukin-12 production by human monocytes infected with Mycobacterium tuberculosis: role of phagocytosis , 1996, Infection and immunity.

[61]  S. Svenson,et al.  Proliferation of distinct human T cell subsets in response to live, killed or soluble extracts of Mycobacterium tuberculosis and Myco. avium , 1996, Clinical and experimental immunology.

[62]  Y. Vodovotz,et al.  Mechanism of suppression of nitric oxide synthase expression by interleukin‐4 in primary mouse macrophages , 1994, Journal of leukocyte biology.

[63]  B. Bloom,et al.  Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages , 1993, Infection and immunity.

[64]  S. Tannenbaum,et al.  Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. , 1982, Analytical biochemistry.

[65]  V. Deretic,et al.  Autophagy in immunity against mycobacterium tuberculosis: a model system to dissect immunological roles of autophagy. , 2009, Current topics in microbiology and immunology.

[66]  G. Rook,et al.  Type 2 cytokine gene activation and its relationship to extent of disease in patients with tuberculosis. , 2000, The Journal of infectious diseases.