Mass Drug Administration and Integrated Control for the World's High‐Prevalence Neglected Tropical Diseases

This year, through mass drug administration, hundreds of millions of the world's poorest people will receive a single annual dose of one or more drugs to treat their parasitic worm infections or trachoma, conditions also known as the neglected tropical diseases (NTDs). Such essential medicines are increasingly being delivered as a package of drugs to target multiple NTDs simultaneously. This integrated approach to NTD control is now recognized as an important and vital global public health solution.

[1]  F. Richards,et al.  Integration of mass drug administration programmes in Nigeria: The challenge of schistosomiasis. , 2006, Bulletin of the World Health Organization.

[2]  E. Ottesen Global programme to eliminate lymphatic filariasis. , 2009, Releve epidemiologique hebdomadaire.

[3]  J. Utzinger,et al.  Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis. , 2008, JAMA.

[4]  Peter J Hotez,et al.  “Rapid-Impact Interventions”: How a Policy of Integrated Control for Africa's Neglected Tropical Diseases Could Benefit the Poor , 2005, PLoS medicine.

[5]  Peter J Hotez,et al.  Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm , 2006, The Lancet.

[6]  J. Vercruysse,et al.  Failure of mebendazole in treatment of human hookworm infections in the southern region of Mali. , 1997, The American journal of tropical medicine and hygiene.

[7]  E. Michael,et al.  Global mapping of lymphatic filariasis. , 1997, Parasitology today.

[8]  Peter J. Hotez,et al.  Neglected Tropical Diseases in Sub-Saharan Africa: Review of Their Prevalence, Distribution, and Disease Burden , 2009, PLoS neglected tropical diseases.

[9]  Annette Olsen,et al.  Efficacy and safety of drug combinations in the treatment of schistosomiasis, soil-transmitted helminthiasis, lymphatic filariasis and onchocerciasis. , 2007, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[10]  Soil-transmitted helminthiasis. Progress report on number of children treated with anthelminthic drugs: an update towards the 2010 global target. , 2008, Releve epidemiologique hebdomadaire.

[11]  A. Fenwick New initiatives against Africa's worms. , 2006, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[12]  Wei Wu,et al.  Oral drug therapy for multiple neglected tropical diseases: a systematic review. , 2007, JAMA.

[13]  Christl A Donnelly,et al.  Morbidity indicators of Schistosoma mansoni: relationship between infection and anemia in Ugandan schoolchildren before and after praziquantel and albendazole chemotherapy. , 2006, The American journal of tropical medicine and hygiene.

[14]  E. Miri,et al.  Triple drug administration (TDA), with praziquantel, ivermectin and albendazole, for the prevention of three neglected tropical diseases in Nigeria , 2008, Annals of tropical medicine and parasitology.

[15]  Meeting of the International Task Force for Disease Eradication, April 2011. , 2011, Releve epidemiologique hebdomadaire.

[16]  C. Knirsch,et al.  The Effect of Azithromycin on Ivermectin Pharmacokinetics—A Population Pharmacokinetic Model Analysis , 2008, PLoS neglected tropical diseases.

[17]  S. Kietinun,et al.  Assessments of pharmacokinetic drug interactions and tolerability of albendazole, praziquantel and ivermectin combinations. , 2006, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[18]  C. Donnelly,et al.  Assessment of ultrasound morbidity indicators of schistosomiasis in the context of large-scale programs illustrated with experiences from Malian children. , 2006, The American journal of tropical medicine and hygiene.

[19]  D. Durrheim,et al.  Current Concepts Control of Neglected Tropical Diseases , 2007 .

[20]  L. Savioli,et al.  Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar. , 2003, Bulletin of the World Health Organization.

[21]  Alan Fenwick,et al.  Recent progress in integrated neglected tropical disease control. , 2007, Trends in parasitology.

[22]  Maria Elena Bottazzi,et al.  The Neglected Tropical Diseases of Latin America and the Caribbean: A Review of Disease Burden and Distribution and a Roadmap for Control and Elimination , 2008, PLoS neglected tropical diseases.

[23]  L. Chitsulo,et al.  Triple Co-Administration of Ivermectin, Albendazole and Praziquantel in Zanzibar: A Safety Study , 2008, PLoS neglected tropical diseases.

[24]  Jeffrey D Sachs,et al.  Incorporating a Rapid-Impact Package for Neglected Tropical Diseases with Programs for HIV/AIDS, Tuberculosis, and Malaria , 2006, PLoS medicine.

[25]  Marcel Tanner,et al.  Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. , 2006, The Lancet. Infectious diseases.

[26]  D. Jamison,et al.  Onchocerciasis -- Disease and Mortality in Sub-Saharan Africa , 2006 .

[27]  P. J. Hooper,et al.  The Global Programme to Eliminate Lymphatic Filariasis: Health Impact after 8 Years , 2008, PLoS neglected tropical diseases.

[28]  Peter J Hotez,et al.  Rescuing the bottom billion through control of neglected tropical diseases , 2009, The Lancet.

[29]  Edridah M Tukahebwa,et al.  Epidemiology and geography of Schistosoma mansoni in Uganda: implications for planning control , 2004, Tropical medicine & international health : TM & IH.

[30]  J. Utzinger,et al.  Food-borne trematodiasis: current chemotherapy and advances with artemisinins and synthetic trioxolanes. , 2007, Trends in parasitology.

[31]  D. Boakye,et al.  Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two-phase epidemiological study , 2007, The Lancet.