MRI evaluation of microvascular obstruction in experimental reperfused acute myocardial infarction using a T1 and T2 preparation pulse sequence

To investigate a T1 and T2 preparation pulse sequence to evaluate microvascular obstruction (MO) in a porcine model of reperfused acute myocardial infarction (AMI).

[1]  C. Higgins,et al.  Influence of severity of myocardial injury on distribution of macromolecules: extravascular versus intravascular gadolinium-based magnetic resonance contrast agents. , 1997, Journal of the American College of Cardiology.

[2]  G. Pohost,et al.  The effect of postinfarction intramyocardial hemorrhage on transverse relaxation time , 1992, Magnetic resonance in medicine.

[3]  K. Sugimura,et al.  Hemorrhagic myocardial infarction after coronary reperfusion detected in vivo by magnetic resonance imaging in humans: prevalence and clinical implications. , 1999, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[4]  Katherine C. Wu,et al.  Quantification and time course of microvascular obstruction by contrast-enhanced echocardiography and magnetic resonance imaging following acute myocardial infarction and reperfusion. , 1998, Journal of the American College of Cardiology.

[5]  S. Kaul,et al.  Microvasculature in acute myocardial ischemia: part II: evolving concepts in pathophysiology, diagnosis, and treatment. , 2004, Circulation.

[6]  G. Korb,et al.  Blood Supply of the Myocardium after Temporary Coronary Occlusion , 1966, Circulation research.

[7]  R. Kloner,et al.  Relationship between no reflow and infarct size as influenced by the duration of ischemia and reperfusion. , 2002, American journal of physiology. Heart and circulatory physiology.

[8]  Maythem Saeed,et al.  Gadomer-enhanced MR imaging in the detection of microvascular obstruction: alleviation with nicorandil therapy. , 2005, Radiology.

[9]  Long-term clinical outcome and predictors of major adverse cardiac events after percutaneous interventions on saphenous vein grafts. , 2001, Journal of the American College of Cardiology.

[10]  K. Okumura,et al.  Angiographic no-reflow phenomenon as a predictor of adverse long-term outcome in patients treated with percutaneous transluminal coronary angioplasty for first acute myocardial infarction. , 2000, Journal of the American College of Cardiology.

[11]  A. Bjørnerud,et al.  Assessment of T1 and T  *2 effects in vivo and ex vivo using iron oxide nanoparticles in steady state—dependence on blood volume and water exchange , 2002, Magnetic resonance in medicine.

[12]  H. A. Oldewurtel,et al.  Dissociation of myocardial sodium and potassium alterations in mild versus severe ischemia. , 1980, The American journal of physiology.

[13]  C. Lorenz,et al.  Measurement of the gadopentetate dimeglumine partition coefficient in human myocardium in vivo: normal distribution and elevation in acute and chronic infarction. , 2001, Radiology.

[14]  H. Kestler,et al.  Sequelae of acute myocardial infarction regarding cardiac structure and function and their prognostic significance as assessed by magnetic resonance imaging. , 2005, European heart journal.

[15]  G. Wright,et al.  Vasodilator Response Assessment in Porcine Myocardium With Magnetic Resonance Relaxometry , 2002, Circulation.

[16]  D Revel,et al.  Differentiation of reversible and irreversible myocardial injury by MR imaging with and without gadolinium-DTPA. , 1986, Radiology.

[17]  F S Prato,et al.  Serial nuclear magnetic resonance imaging of acute myocardial infarction with and without reperfusion. , 1988, American heart journal.

[18]  J. Schulz-Menger,et al.  T1 mapping in patients with acute myocardial infarction. , 2003, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[19]  A. Carpentier,et al.  Microcirculatory changes following early reperfusion in experimentel myocardial infarction , 1976, Virchows Archiv A.

[20]  C. Kramer.  The prognostic significance of microvascular obstruction after myocardial infarction as defined by cardiovascular magnetic resonance. , 2005, European heart journal.

[21]  L. Ohno-Machado,et al.  No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention. , 2003, American heart journal.

[22]  George Dangas,et al.  Impact of normalized myocardial perfusion after successful angioplasty in acute myocardial infarction. , 2002, Journal of the American College of Cardiology.

[23]  R. Schwartz.  Microvascular obstruction in acute coronary syndromes: Onward to a new therapeutic target , 2005, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[24]  R. Judd,et al.  Physiological basis of myocardial contrast enhancement in fast magnetic resonance images of 2-day-old reperfused canine infarcts. , 1995, Circulation.

[25]  Katherine C. Wu,et al.  Microvascular obstruction and left ventricular remodeling early after acute myocardial infarction. , 2000, Circulation.

[26]  E. Topol,et al.  Recognition of the importance of embolization in atherosclerotic vascular disease. , 2000, Circulation.

[27]  Assessment of reperfused acute myocardial infarction with two-phase contrast-enhanced helical CT : prediction of left ventricular function and wall thickness , 2006 .

[28]  Katherine C. Wu,et al.  Prognostic significance of microvascular obstruction by magnetic resonance imaging in patients with acute myocardial infarction. , 1998, Circulation.

[29]  Yasuo Ohashi,et al.  Assessment of reperfused acute myocardial infarction with two-phase contrast-enhanced helical CT: prediction of left ventricular function and wall thickness. , 2005, Radiology.

[30]  S. Bishop,et al.  Assessment of Postreperfusion Myocardial Hemorrhage Using Proton NMR Imaging at 1.5 T , 1992, Circulation.

[31]  R. Kloner,et al.  The "no-reflow" phenomenon after temporary coronary occlusion in the dog. , 1974, The Journal of clinical investigation.

[32]  R. Henkelman,et al.  Practical Implementation and Optimization of One‐shot T1 imaging , 1991, Magnetic resonance in medicine.

[33]  L. Becker,et al.  Progressive failure of coronary flow during reperfusion of myocardial infarction: documentation of the no reflow phenomenon with positron emission tomography. , 1990, Journal of the American College of Cardiology.

[34]  R. Kloner,et al.  No-Reflow Phenomenon Persists Long-Term After Ischemia/Reperfusion in the Rat and Predicts Infarct Expansion , 2003, Circulation.

[35]  R. Herfkens,et al.  Nuclear magnetic resonance imaging of acute myocardial infarction in dogs: alterations in magnetic relaxation times. , 1983, The American journal of cardiology.

[36]  S. Iliceto,et al.  Duration of ischemia is a major determinant of transmurality and severe microvascular obstruction after primary angioplasty: a study performed with contrast-enhanced magnetic resonance. , 2005, Journal of the American College of Cardiology.

[37]  Henry R. Halperin,et al.  Contrast-Enhanced Multidetector Computed Tomography Viability Imaging After Myocardial Infarction: Characterization of Myocyte Death, Microvascular Obstruction, and Chronic Scar , 2006, Circulation.

[38]  F. Epstein,et al.  Infarct involution and improved function during healing of acute myocardial infarction: the role of microvascular obstruction. , 2004, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[39]  E R McVeigh,et al.  Magnitude and time course of microvascular obstruction and tissue injury after acute myocardial infarction. , 1998, Circulation.

[40]  Gerald Wisenberg,et al.  Determining the extent to which delayed‐enhancement images reflect the partition‐coefficient of Gd‐DTPA in canine studies of reperfused and unreperfused myocardial infarction , 2004, Magnetic resonance in medicine.

[41]  R. Kim,et al.  Microvascular Integrity and the Time Course of Myocardial Sodium Accumulation After Acute Infarction , 2000, Circulation research.

[42]  M. Hori,et al.  Clinical implications of the 'no reflow' phenomenon. A predictor of complications and left ventricular remodeling in reperfused anterior wall myocardial infarction. , 1996, Circulation.

[43]  M. Kern,et al.  The coronary no-reflow phenomenon: a review of mechanisms and therapies. , 2001, European heart journal.