Genetics in endocrinology: genetic variation in deiodinases: a systematic review of potential clinical effects in humans.
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[1] M. Sapio,et al. Prevalence of Dio2T92A polymorphism and its association with thyroid autoimmunity , 2013, Journal of Endocrinological Investigation.
[2] Lorna M. Lopez,et al. A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function , 2013, PLoS genetics.
[3] K. Alzoubi,et al. The role of type II deiodinase polymorphisms in clinical management of hypothyroid patients treated with levothyroxine. , 2013, Experimental and clinical endocrinology & diabetes.
[4] B. Alina,et al. Thr92Ala Polymorphism of Human Type 2 Deiodinase Gene (hD2) Affects the Development of Graves' Disease, Treatment Efficiency, and Rate of Remission , 2012, Clinical & developmental immunology.
[5] A. Morgan,et al. Selenium, Selenoprotein Genes and Crohn’s Disease in a Case-Control Population from Auckland, New Zealand , 2012, Nutrients.
[6] C. Davis,et al. Selenoproteins and cancer prevention. , 2012, Annual review of nutrition.
[7] F. Celi,et al. The -258A/G (SNP rs12885300) polymorphism of the human type 2 deiodinase gene is associated with a shift in the pattern of secretion of thyroid hormones following a TRH-induced acute rise in TSH. , 2012, European journal of endocrinology.
[8] F. Stamatian,et al. The effect of the D1-C785T polymorphism in the type 1 iodothyronine deiodinase gene on the circulating thyroid hormone levels in Romanian women with preeclampsia. Association with the degree of severity and pregnancy outcome of preeclampsia , 2012, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
[9] P. Slagboom,et al. Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues , 2012, Annals of the rheumatic diseases.
[10] T. Visser,et al. Changes within the thyroid axis after long‐term TSH‐suppressive levothyroxine therapy , 2012, Clinical endocrinology.
[11] J. Bassett,et al. Thyroid hormone metabolism in skeletal development and adult bone maintenance , 2012, Trends in Endocrinology & Metabolism.
[12] B. Casey,et al. Subclinical Thyroid Disease and the Incidence of Hypertension in Pregnancy , 2012, Obstetrics and gynecology.
[13] C. Bogardus,et al. Association analyses of variants in the DIO2 gene with early-onset type 2 diabetes mellitus in Pima Indians. , 2012, Thyroid : official journal of the American Thyroid Association.
[14] M. Pino-Yanes,et al. Type 2 deiodinase and host responses of sepsis and acute lung injury. , 2011, American journal of respiratory cell and molecular biology.
[15] Fuchang Zhang,et al. A Family-based Association Study of DIO2 and children mental retardation in the Qinba region of China , 2011, Journal of Human Genetics.
[16] M. van Wely,et al. Significance of (sub)clinical thyroid dysfunction and thyroid autoimmunity before conception and in early pregnancy: a systematic review. , 2011, Human reproduction update.
[17] S. Beach,et al. The relationship of deiodinase 1 genotype and thyroid function to lifetime history of major depression in three independent populations , 2011, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[18] S. le Cessie,et al. The type 2 deiodinase ORFa-Gly3Asp polymorphism (rs12885300) influences the set point of the hypothalamus-pituitary-thyroid axis in patients treated for differentiated thyroid carcinoma. , 2011, The Journal of clinical endocrinology and metabolism.
[19] J. Houwing-Duistermaat,et al. Osteoarthritis susceptibility genes influence the association between hip morphology and osteoarthritis. , 2011, Arthritis and rheumatism.
[20] A. Hofman,et al. A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels. , 2011, European journal of endocrinology.
[21] J. Dora,et al. D2 Thr92Ala and PPARγ2 Pro12Ala Polymorphisms Interact in the Modulation of Insulin Resistance in Type 2 Diabetic Patients , 2011, Obesity.
[22] S. Wajner,et al. Deiodinases: the balance of thyroid hormone: type 1 iodothyronine deiodinase in human physiology and disease. , 2011, The Journal of endocrinology.
[23] S. Wajner,et al. Type 1 iodothyronine deiodinase in human physiology and disease Deiodinases: the balance of thyroid hormone , 2011 .
[24] A. Magno,et al. The calcium-sensing receptor: a molecular perspective. , 2011, Endocrine reviews.
[25] F. Celi,et al. The Thr92Ala 5' type 2 deiodinase gene polymorphism is associated with a delayed triiodothyronine secretion in response to the thyrotropin-releasing hormone-stimulation test: a pharmacogenomic study. , 2010, Thyroid : official journal of the American Thyroid Association.
[26] P. Slagboom,et al. 012 FUNCTIONAL CHARACTERIZATION OF OA RISK POLYMORPHISM RS225014 AT DIO2 IN HUMAN OA CARTILAGE , 2010 .
[27] A. Maia,et al. Association of the type 2 deiodinase Thr92Ala polymorphism with type 2 diabetes: case-control study and meta-analysis. , 2010, European journal of endocrinology.
[28] J. Houwing-Duistermaat,et al. Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility , 2010, Annals of the rheumatic diseases.
[29] J. Romijn,et al. The type 2 deiodinase Thr92Ala polymorphism is associated with increased bone turnover and decreased femoral neck bone mineral density , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[30] Y. Xiong,et al. Association study between polymorphisms in selenoprotein genes and susceptibility to Kashin-Beck disease. , 2010, Osteoarthritis and cartilage.
[31] R. H. Bassett,et al. Optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts , 2010, Proceedings of the National Academy of Sciences.
[32] N. Timpson,et al. The effect of genetic variation in PDE8B and DIO1 on thyroid hormone levels , 2010 .
[33] J P Vandenbroucke,et al. How to assess the external validity of therapeutic trials: a conceptual approach. , 2010, International journal of epidemiology.
[34] Yongyong Shi,et al. Association of genetic polymorphisms in the type II deiodinase gene with bipolar disorder in a subset of Chinese population , 2009, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[35] E. Grineva,et al. Type 2 deiodinase Thr92Ala polymorphism impact on clinical course and myocardial remodeling in patients with Graves' disease , 2009, Cell cycle.
[36] E. Fliers,et al. Thr92Ala polymorphism in the type 2 deiodinase is not associated with T4 dose in athyroid patients or patients with Hashimoto thyroiditis , 2009, Clinical endocrinology.
[37] B. Glaser,et al. Preliminary evidence that a functional polymorphism in type 1 deiodinase is associated with enhanced potentiation of the antidepressant effect of sertraline by triiodothyronine. , 2009, Journal of affective disorders.
[38] A. Hofman,et al. Impact of thyroid function and polymorphisms in the type 2 deiodinase on blood pressure: the Rotterdam Study and the Rotterdam Scan Study , 2009, Clinical endocrinology.
[39] A. Uitterlinden,et al. The effect of genetic variation in the type 1 deiodinase gene on the interindividual variation in serum thyroid hormone levels: an investigation in healthy Danish twins , 2009, Clinical endocrinology.
[40] A. Bianco,et al. For some, L-thyroxine replacement might not be enough: a genetic rationale. , 2009, The Journal of clinical endocrinology and metabolism.
[41] T. Frayling,et al. Common variation in the DIO2 gene predicts baseline psychological well-being and response to combination thyroxine plus triiodothyronine therapy in hypothyroid patients. , 2009, The Journal of clinical endocrinology and metabolism.
[42] T. Frayling,et al. Common variation in the DIO2 gene predicts baseline psychological well-being and response to combination T4/T3 therapy in patients on thyroid hormone replacement , 2009 .
[43] D. Hernandez,et al. A common variation in deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triiodothyronine. , 2008, The Journal of clinical endocrinology and metabolism.
[44] Cornelia M van Duijn,et al. Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. , 2008, Human molecular genetics.
[45] D. Levy,et al. Lack of association between the type 2 deiodinase A/G polymorphism and hypertensive traits: the Framingham Heart Study. , 2008, Hypertension.
[46] T. Montesano,et al. Type 2 deiodinase polymorphism (threonine 92 alanine) predicts L-thyroxine dose to achieve target thyrotropin levels in thyroidectomized patients. , 2008, The Journal of clinical endocrinology and metabolism.
[47] Vincenzo Trischitta,et al. Interaction of DIO2 T92A and PPARγ2 P12A Polymorphisms in the Modulation of Metabolic Syndrome , 2007, Obesity.
[48] L. Liang,et al. A genome-wide association study of global gene expression , 2007, Nature Genetics.
[49] G. Ness,et al. Activation of the hepatic LDL receptor promoter by thyroid hormone. , 2007, Biochimica et biophysica acta.
[50] A. Maia,et al. Type 2 deiodinase Thr92Ala polymorphism is not associated with arterial hypertension in type 2 diabetes mellitus patients. , 2007, Hypertension.
[51] C. Fox,et al. The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study. , 2007, Thyroid : official journal of the American Thyroid Association.
[52] P. Hopkins,et al. Ala92 Type 2 Deiodinase Allele Increases Risk for the Development of Hypertension , 2007, Hypertension.
[53] A. Hofman,et al. The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe. , 2007, The Journal of clinical endocrinology and metabolism.
[54] T. Visser,et al. Genetic variation in thyroid hormone pathway genes; polymorphisms in the TSH receptor and the iodothyronine deiodinases. , 2006, European journal of endocrinology.
[55] F. Celi,et al. Functional characterization of the 258 A/G (D2-ORFa-Gly3Asp) human type-2 deiodinase polymorphism: a naturally occurring variant increases the enzymatic activity by removing a putative repressor site in the 5' UTR of the gene. , 2006, Thyroid : official journal of the American Thyroid Association.
[56] J. Tijssen,et al. Thyrotropin, but not a polymorphism in type II deiodinase, predicts response to paroxetine in major depression. , 2006, European journal of endocrinology.
[57] M. Mori,et al. Regulation of iodothyronine deiodinase and roles of thyroid hormones in human coronary artery smooth muscle cells. , 2006, Atherosclerosis.
[58] A. Shuldiner,et al. The Thr92Ala deiodinase type 2 (DIO2) variant is not associated with type 2 diabetes or indices of insulin resistance in the old order of Amish. , 2005, Thyroid.
[59] A. Gogakos,et al. Thyroid and bone. , 2005, Archives of biochemistry and biophysics.
[60] J. Tijssen,et al. Polymorphisms in type 2 deiodinase are not associated with well-being, neurocognitive functioning, and preference for combined thyroxine/3,5,3'-triiodothyronine therapy. , 2005, The Journal of clinical endocrinology and metabolism.
[61] J. Harney,et al. Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans. , 2005, The Journal of clinical investigation.
[62] F. Celi,et al. Peripheral metabolism of thyroid hormone and glucose homeostasis. , 2005, Thyroid : official journal of the American Thyroid Association.
[63] C. Tabin,et al. The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate , 2005, Nature Cell Biology.
[64] A. Uitterlinden,et al. A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters. , 2005, American journal of physiology. Endocrinology and metabolism.
[65] J. Harney,et al. The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus. , 2005, The Journal of clinical endocrinology and metabolism.
[66] R. Turakulov,et al. Screening of SNPs at 18 positional candidate genes, located within the GD-1 locus on chromosome 14q23-q32, for susceptibility to Graves' disease: a TDT study. , 2004, Molecular genetics and metabolism.
[67] S. Duan,et al. Positive association of the DIO2 (deiodinase type 2) gene with mental retardation in the iodine-deficient areas of China , 2004, Journal of Medical Genetics.
[68] B. Larijani,et al. Thyroid hormone alteration in pre-eclamptic women , 2004, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
[69] J. Harney,et al. The mRNA structure has potent regulatory effects on type 2 iodothyronine deiodinase expression. , 2002, Molecular endocrinology.
[70] A. Shuldiner,et al. Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor. , 2002, Diabetes.
[71] P. Larsen,et al. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. , 2002, Endocrine reviews.
[72] J. Harney,et al. The Human Type 2 Iodothyronine Deiodinase Is a Selenoprotein Highly Expressed in a Mesothelioma Cell Line* , 2001, Journal of Biological Chemistry.
[73] J. Harney,et al. Regional physiological adaptation of the central nervous system deiodinases to iodine deficiency. , 2001, American journal of physiology. Endocrinology and metabolism.
[74] D. Stevens,et al. Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation. , 2000, Endocrinology.
[75] G. Canettieri,et al. Structural organization and chromosomal localization of the human type II deiodinase gene. , 2000, European journal of endocrinology.
[76] M. Rayman,et al. The importance of selenium to human health , 2000, The Lancet.
[77] M. Başbuğ,et al. Correlation between maternal thyroid function tests and endothelin in preeclampsia-eclampsia. , 1999, Obstetrics and gynecology.
[78] J. Köhrle. Local activation and inactivation of thyroid hormones: the deiodinase family , 1999, Molecular and Cellular Endocrinology.
[79] A. Dugbartey. Neurocognitive aspects of hypothyroidism. , 1998, Archives of internal medicine.
[80] W. Croteau,et al. Expression of the Type II Iodothyronine Deiodinase in Cultured Rat Astrocytes Is Selenium-dependent* , 1997, The Journal of Biological Chemistry.
[81] I. Klein,et al. Acute effects of thyroid hormone on vascular smooth muscle. , 1996, Thyroid : official journal of the American Thyroid Association.
[82] A. Colak,et al. 1508 – Association Study Of The Dio2 Gene As a Susceptibility Candidate For Schizophrenia In The Turkish Population; a Case-control Study , 2013, European psychiatry.
[83] K. Pirkalani,et al. 883 – Questionnaire On Sexual Attitude And Function 2009: a Novel Clinical And Epidemiological Computer Based Tool , 2013, European psychiatry.
[84] J. Kaufman,et al. Bone mass in young men is inversely associated with free triiodothyronine, but not with polymorphisms in deiodinases , 2011 .
[85] J. V. D. van der Post,et al. Significance of (sub)clinical thyroid dysfunction and thyroid autoimmunity before conception and in early pregnancy: a systematic review. , 2011, Human reproduction update.
[86] T. Hansen,et al. Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects. , 2007, The Journal of clinical endocrinology and metabolism.
[87] A. Uitterlinden,et al. A polymorphism in type I deiodinase is associated with circulating free insulin-like growth factor I levels and body composition in humans. , 2005, The Journal of clinical endocrinology and metabolism.
[88] A. Uitterlinden,et al. Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects. , 2003, The Journal of clinical endocrinology and metabolism.
[89] A. Heinz,et al. Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain , 2002, Molecular Psychiatry.
[90] J. Oppenheimer,et al. Functional relationship of thyroid hormone-induced lipogenesis, lipolysis, and thermogenesis in the rat. , 1991, The Journal of clinical investigation.