New insights into the etiology of preeclampsia: identification of key elusive factors for the vascular complications.

[1]  A. Hingorani,et al.  Prospective Study of Placental Angiogenic Factors and Maternal Vascular Function Before and After Preeclampsia and Gestational Hypertension , 2010, Circulation.

[2]  S. Blackwell,et al.  Angiotensin Receptor Agonistic Autoantibody–Mediated Tumor Necrosis Factor-&agr; Induction Contributes to Increased Soluble Endoglin Production in Preeclampsia , 2010, Circulation.

[3]  B. Fazekas de St. Groth,et al.  Systemic Increase in the Ratio between Foxp3+ and IL-17-Producing CD4+ T Cells in Healthy Pregnancy but Not in Preeclampsia1 , 2009, The Journal of Immunology.

[4]  Asif Ahmed,et al.  Can the biology of VEGF and haem oxygenases help solve pre-eclampsia? , 2009, Biochemical Society transactions.

[5]  T. Okai,et al.  Cellular mRNA expressions of anti‐oxidant factors in the blood of preeclamptic women , 2009, Prenatal diagnosis.

[6]  A. Gruber,et al.  Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model , 2009, Journal of cellular and molecular medicine.

[7]  M. Saint-Geniez,et al.  TGF-β Is Required for Vascular Barrier Function, Endothelial Survival and Homeostasis of the Adult Microvasculature , 2009, PloS one.

[8]  T. Okai,et al.  Gene expression in chorionic villous samples at 11 weeks' gestation from women destined to develop preeclampsia , 2008, Prenatal diagnosis.

[9]  A. Fazleabas,et al.  Placental angiogenesis markers sFlt-1 and PlGF: response to cigarette smoke. , 2007, American journal of obstetrics and gynecology.

[10]  Graeme N. Smith,et al.  Effect of cigarette smoke on placental antioxidant enzyme expression. , 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

[11]  A. Bérard,et al.  Risk of congenital anomalies in pregnant users of statin drugs , 2007, British journal of clinical pharmacology.

[12]  Asif Ahmed,et al.  Negative Regulation of Soluble Flt-1 and Soluble Endoglin Release by Heme Oxygenase-1 , 2007, Circulation.

[13]  B. Sibai,et al.  Soluble endoglin and other circulating antiangiogenic factors in preeclampsia , 2007 .

[14]  D. Mukhopadhyay,et al.  Direct Evidence for Endothelial Vascular Endothelial Growth Factor Receptor-1 Function in Nitric Oxide–Mediated Angiogenesis , 2006, Circulation research.

[15]  I. Tkáč,et al.  Beneficial effect of simvastatin treatment on LDL oxidation and antioxidant protection is more pronounced in combined hyperlipidemia than in hypercholesterolemia. , 2006, Pharmacological research.

[16]  T. Libermann,et al.  Soluble endoglin contributes to the pathogenesis of preeclampsia , 2006, Nature Medicine.

[17]  W. März,et al.  Simvastatin Versus Ezetimibe: Pleiotropic and Lipid-Lowering Effects on Endothelial Function in Humans , 2005, Circulation.

[18]  S. Dimmeler,et al.  Risk factors for coronary artery disease, circulating endothelial progenitor cells, and the role of HMG-CoA reductase inhibitors. , 2005, Kidney international.

[19]  S. Stevens,et al.  Nitric Oxide Mediates the Effect of Fluvastatin on Intercellular Adhesion Molecule-1 and Platelet EndothelialCell Adhesion Molecule-1 Expressionon Human Endothelial cells , 2005, Annals of vascular surgery.

[20]  D. Eidelman,et al.  Downloaded from http://circres.ahajournals.org / by guest on February 23, 2013A Role for Endoglin in Coupling eNOS Activity and Regulating Vascular Tone Revealed in Hereditary , 2022 .

[21]  J. Hirsh,et al.  Use of antithrombotic agents during pregnancy: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. , 2004, Chest.

[22]  A. Zeiher,et al.  Antioxidant Effects of Statins via S-Nitrosylation and Activation of Thioredoxin in Endothelial Cells: A Novel Vasculoprotective Function of Statins , 2004, Circulation.

[23]  Napoleone Ferrara,et al.  Vascular endothelial growth factor: basic science and clinical progress. , 2004, Endocrine reviews.

[24]  D. Stevenson,et al.  End Tidal Carbon Monoxide Levels are Lower in Women with Gestational Hypertension and Pre-eclampsia , 2004, Journal of Perinatology.

[25]  Patty J. Lee,et al.  Small Interfering RNA Targeting Heme Oxygenase-1 Enhances Ischemia-Reperfusion-induced Lung Apoptosis* , 2004, Journal of Biological Chemistry.

[26]  J. López-Novoa,et al.  Endoglin regulates nitric oxide‐dependent vasodilatation , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[27]  T. Spector,et al.  Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies , 2004, The New England journal of medicine.

[28]  J. Kupiec-Weglinski,et al.  Heme oxygenase system in ischemia and reperfusion injury. , 2003, Annals of transplantation.

[29]  R. Flavell,et al.  Disruption of TGF-β signaling in T cells accelerates atherosclerosis , 2003 .

[30]  S. Cnattingius,et al.  Adverse pregnancy outcomes in snuff users. , 2003, American journal of obstetrics and gynecology.

[31]  T. Libermann,et al.  Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia , 2003 .

[32]  R. Busuttil,et al.  A novel strategy against ischemia and reperfusion injury: cytoprotection with heme oxygenase system. , 2002, Transplant immunology.

[33]  J. Oyama,et al.  Gene Therapy Strategy for Long-Term Myocardial Protection Using Adeno-Associated Virus-Mediated Delivery of Heme Oxygenase Gene , 2002, Circulation.

[34]  T. Meinertz,et al.  Endothelial Dysfunction, Oxidative Stress, and Risk of Cardiovascular Events in Patients With Coronary Artery Disease , 2001, Circulation.

[35]  James L. Park,et al.  Heme oxygenase-1 protects against vascular constriction and proliferation , 2001, Nature Medicine.

[36]  D. Stevenson,et al.  End-tidal carbon monoxide measurements in women with pregnancy-induced hypertension and preeclampsia. , 2000, American journal of obstetrics and gynecology.

[37]  S. Thom,et al.  Adaptive responses and apoptosis in endothelial cells exposed to carbon monoxide. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[38]  A. Conde-Agudelo,et al.  Cigarette smoking during pregnancy and risk of preeclampsia: a systematic review. , 1999, American journal of obstetrics and gynecology.

[39]  A. Choi,et al.  Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. , 1999, The Journal of clinical investigation.

[40]  A. Ahmed,et al.  Hemeoxygenase-1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy. , 1998, The Journal of clinical investigation.

[41]  Jeffrey S. Ginsberg,et al.  Use of antithrombotic agents during pregnancy. , 1992, Chest.

[42]  M. Beckmann,et al.  Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction. , 2007, Clinical science.

[43]  F. Kabbinavar,et al.  Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[44]  Asif Ahmed,et al.  Induction of Placental Heme Oxygenase-1 Is Protective Against TNFα-induced Cytotoxicity and Promotes Vessel Relaxation , 2000, Molecular medicine.

[45]  Asif Ahmed Heparin-binding angiogenic growth factors in pregnancy , 1997 .

[46]  R. Tyrrell,et al.  Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. , 1989, Proceedings of the National Academy of Sciences of the United States of America.