Modelling cholera in periodic environments

We propose a deterministic compartmental model for cholera dynamics in periodic environments. The model incorporates seasonal variation into a general formulation for the incidence (or, force of infection) and the pathogen concentration. The basic reproduction number of the periodic model is derived, based on which a careful analysis is conducted on the epidemic and endemic dynamics of cholera. Several specific examples are presented to demonstrate this general model, and numerical simulation results are used to validate the analytical prediction.

[1]  Xiao-Qiang Zhao,et al.  Threshold Dynamics for Compartmental Epidemic Models in Periodic Environments , 2008 .

[2]  Zhenguo Bai,et al.  Global dynamics of an SEIRS epidemic model with periodic vaccination and seasonal contact rate , 2012 .

[3]  Alessandro Margheri,et al.  Persistence in seasonally forced epidemiological models , 2012, Journal of mathematical biology.

[4]  J. Watmough,et al.  Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission. , 2002, Mathematical biosciences.

[5]  David L. Smith,et al.  Estimating the reproductive numbers for the 2008–2009 cholera outbreaks in Zimbabwe , 2011, Proceedings of the National Academy of Sciences.

[6]  D. Earn,et al.  Multiple Transmission Pathways and Disease Dynamics in a Waterborne Pathogen Model , 2010, Bulletin of mathematical biology.

[7]  Nicolas Bacaër Approximation of the Basic Reproduction Number R0 for Vector-Borne Diseases with a Periodic Vector Population , 2007, Bulletin of mathematical biology.

[8]  David M. Hartley,et al.  Hyperinfectivity: A Critical Element in the Ability of V. cholerae to Cause Epidemics? , 2005, PLoS medicine.

[9]  Uniform Persistence in Processes With Application to Nonautonomous Competitive Models , 2001 .

[10]  Threshold dynamics of a bacillary dysentery model withseasonal fluctuation , 2010 .

[11]  C. Codeço Endemic and epidemic dynamics of cholera: the role of the aquatic reservoir , 2001, BMC infectious diseases.

[12]  J. Glenn Morris,et al.  Cholera transmission: the host, pathogen and bacteriophage dynamic , 2009, Nature Reviews Microbiology.

[13]  Jin Wang,et al.  Computing the basic reproductive numbers for epidemiological models in nonhomogeneous environments , 2014, Appl. Math. Comput..

[14]  Jin Wang,et al.  On the global stability of a generalized cholera epidemiological model , 2012, Journal of biological dynamics.

[15]  Nicolas Bacaër,et al.  Growth rate and basic reproduction number for population models with a simple periodic factor. , 2007, Mathematical biosciences.

[16]  Zhisheng Shuai,et al.  Global dynamics of cholera models with differential infectivity. , 2011, Mathematical biosciences.

[17]  Shu Liao,et al.  A generalized cholera model and epidemic–endemic analysis , 2012, Journal of biological dynamics.

[18]  Jin Wang,et al.  Stability analysis and application of a mathematical cholera model. , 2011, Mathematical biosciences and engineering : MBE.

[19]  Xiao-Qiang Zhao,et al.  A periodic epidemic model in a patchy environment , 2007 .

[20]  Nicolas Bacaër,et al.  The epidemic threshold of vector-borne diseases with seasonality , 2006, Journal of mathematical biology.

[21]  Xiao-Qiang Zhao,et al.  Dynamical systems in population biology , 2003 .