The Possible Etiological Role of CMV & EBV Latent Infections in Polycystic Ovary Syndrome Iraqi patients

To investigate whether or not there is a causal relationship between latent infection of CMV & EBV and polycystic ovary syndrome (PCOS) in a sample of Iraqi women, 60 blood samples were obtained from PCOS patients with age range ( 20-40) years who attended Kamal Al-Samaria IVF Center in Baghdad-Iraq, and (30) blood samples from apparently healthy age-matched women. By using ELISA technique anti-CMV & anti-EBV IgG specific Abs were explored in sera separated from blood samples of both patients and controls. The results revealed that 10 (≈16.7%) out of the 60 PCOS women were positive for CMV compared to only one (≈3.3%) positive case recorded in the control group. On the other hand, positive results of anti-EBV IgG Abs were recorded in 27 (≈ 45%) out of the 60 cases of women with PCOS, in comparison, no one (0%) of the 30 control women was positive for this test. Such results provide objective indications for these viruses as being involved in an aspect of causal events behind PCOS.

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