Improving low-dose X-ray CT images by Weighted Intensity Averaging over Large-scale Neighborhoods

How to reduce the radiation dose delivered to the patients is always an important concern since the introduction of computed tomography (CT). With respect to patients' care, the least possible radiation dose is demanded. Though clinically desired, low-dose CT (LDCT) images tend to be severely degraded by quantum noise and artifacts under low dose scan protocols. This paper proposes to improve the LDCT images by Weighted Intensity Averaging over Large-scale Neighborhoods (WIA-LN). In the implementation of the proposed WIA-LN method, the processed pixel intensities are from a selective weighted intensity averaging of the pixels belonging to different organs or attenuation tissues within large-scale neighborhoods. Effective suppression of noise and artifacts in LDCT images without obvious loss of fine anatomic features are realized. In experiment, CT images of different doses from a Siemens CT with 16 detector rows are used. Results validate an excellent performance of the proposed approach in improving clinical LDCT images.

[1]  J. Hsieh Adaptive streak artifact reduction in computed tomography resulting from excessive x-ray photon noise. , 1998, Medical physics.

[2]  B. Schmidt,et al.  A PC program for estimating organ dose and effective dose values in computed tomography , 1999, European Radiology.

[3]  Pierrick Coupé,et al.  An Optimized Blockwise Nonlocal Means Denoising Filter for 3-D Magnetic Resonance Images , 2008, IEEE Transactions on Medical Imaging.

[4]  Rainer Raupach,et al.  The effect of dose reduction and feasibility of edge-preserving noise reduction on the detection of liver lesions using MSCT , 2007, European Radiology.

[5]  P. Yger,et al.  An Optimized Blockwise Non Local Means Denoising Filter for 3D Magnetic Resonance Images , 2007 .

[6]  Rainer Raupach,et al.  CT images of abdomen and pelvis: effect of nonlinear three-dimensional optimized reconstruction algorithm on image quality and lesion characteristics. , 2005, Radiology.

[7]  Jean-Michel Morel,et al.  A non-local algorithm for image denoising , 2005, 2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'05).

[8]  K S Lee,et al.  Low-Dose, Volumetric Helical CT: Image Quality, Radiation Dose, and Usefulness for Evaluation of Bronchiectasis , 2000, Investigative radiology.

[9]  Kazuo Awai,et al.  Improvement of Low-Contrast Detectability in Low-Dose Hepatic Multidetector Computed Tomography Using a Novel Adaptive Filter: Evaluation With a Computer-Simulated Liver Including Tumors , 2006, Investigative radiology.

[10]  D A Pierce,et al.  Radiation-Related Cancer Risks at Low Doses among Atomic Bomb Survivors , 2000, Radiation research.

[11]  M. Kalra,et al.  Strategies for CT radiation dose optimization. , 2004, Radiology.

[12]  D. Brenner,et al.  Computed tomography--an increasing source of radiation exposure. , 2007, The New England journal of medicine.

[13]  Guillermo Sapiro,et al.  Fast image and video denoising via nonlocal means of similar neighborhoods , 2005, IEEE Signal Processing Letters.

[14]  Thomas L Toth,et al.  Low-dose CT of the abdomen: evaluation of image improvement with use of noise reduction filters pilot study. , 2003, Radiology.