Adhesive Arachnoiditis With Extensive Syringomyelia and Giant Arachnoid Cyst After Spinal and Epidural Anesthesia: A Case Report

Study Design. A case report of a patient with adhesive arachnoiditis after combined spinal and epidural anesthesia. Objective. To report an extremely rare case of paraplegia due to adhesive arachnoiditis with extensive syringomyelia (ES) and a giant anterior arachnoid spinal cyst (AASC) after spinal and epidural anesthesia for obstetric surgery. Summary of Background Data. Progressive inflammation of the arachnoid mater due to trauma, infection, or hydrocortisone was reported as early as the 1970s. However, coexistence of ES and a giant AASC after spinal and epidural anesthesia is extremely rare. Methods. A 29-year-old woman suffered from sudden anuresis 5 months after spinal and epidural anesthesia for a cesarean section and subsequently experienced paraplegia and numbness below the chest. Magnetic resonance imaging showed an AASC compressing the spinal cord at T1–T6 and an adhesive lesion at T7. Posterior laminectomy at T6–T7 and adhesiolysis for arachnoid adhesion at T7 were performed. Although there was slight recovery of locomotive function postoperatively, it gradually worsened until 3 years after surgery. Magnetic resonance imaging at that time demonstrated a giant AASC and ES at the lower-thoracic cord. The cord compressed by the AASC became thinner sagittally. Secondary surgery involving posterior laminectomy at T5–T6 and insertion of a cyst-peritoneal shunt into the AASC was performed. Results. The patient could walk without a cane 3 years after the shunt operation, although numbness and motor weakness of the lower extremities remained. Magnetic resonance imaging 3 years after the shunt operation showed a reduction of the AASC and decompression of the cord despite no improvement in ES. Conclusion. This is the first report of a patient with a giant AASC and ES caused by spinal and epidural anesthesia. Although the optimal surgical treatment for these conditions remains unclear, shunting of the cyst effectively prevented the progression of symptoms.

[1]  G. Comi,et al.  Giant Anterior Arachnoid Cyst Associated With Syringomyelia: Implications for Treatment and Follow-up , 2010, Spine.

[2]  L. Albuquerque,et al.  Giant intradural extramedullary arachnoid cyst of the thoracic spine , 2009, Journal of Clinical Neuroscience.

[3]  M. Wee,et al.  Obstetric epidurals and chronic adhesive arachnoiditis. , 2004, British journal of anaesthesia.

[4]  C. Howell,et al.  Randomised study of long term outcome after epidural versus non-epidural analgesia during labour , 2002, BMJ : British Medical Journal.

[5]  S. Hassenbusch,et al.  Evidence-based review of the literature on intrathecal delivery of pain medication. , 2000, Journal of pain and symptom management.

[6]  D. Pareyson,et al.  Imaging and outcome in severe complications of lumbar epidural anaesthesia: report of 16 cases , 2000, Neuroradiology.

[7]  O. Spigset,et al.  Peripheral neurologic deficits in relation to subarachnoid or epidural administration of local anesthetics for surgery , 1997, Acta anaesthesiologica Scandinavica.

[8]  M. Lahdensuu,et al.  Severe complications associated with epidural and spinal anaesthesias in Finland 1987–1993 A study based on patient insurance claims , 1997, Acta anaesthesiologica Scandinavica.

[9]  Aldrete Ja,et al.  Intrathecal hematoma and arachnoiditis after prophylactic blood patch through a catheter. , 1997 .

[10]  H. Renck Neurological complications of central nerve blocks , 1995, Acta anaesthesiologica Scandinavica.

[11]  N. Dahlgren,et al.  Neurological complications after anaesthesia. A follow‐up of 18 000 spinal and epidural anaesthetics performed over three years , 1995, Acta anaesthesiologica Scandinavica.

[12]  S. Abram,et al.  Complications Associated With Epidural Steroid Injections , 1995, Regional Anesthesia & Pain Medicine.

[13]  T. Todo,et al.  Lumbar adhesive arachnoiditis following attempted epidural anesthesia--case report. , 1995, Neurologia medico-chirurgica.

[14]  M. Gemma,et al.  Neurologic symptoms after epidural anaesthesia. Report of three cases , 1994, Acta anaesthesiologica Scandinavica.

[15]  B. Green,et al.  Complications of epidural anesthesia: MR appearance of abnormalities. , 1991, Radiology.

[16]  H. Wulf,et al.  Postmortem findings after epidural anaesthesia , 1990, Anaesthesia.

[17]  D. Pareyson,et al.  Epidural anaesthesia and spinal arachnoiditis , 1989, Anaesthesia.

[18]  D. A. Nelson Dangers from methylprednisolone acetate therapy by intraspinal injection. , 1988, Archives of neurology.

[19]  P. Rosenberg,et al.  Effects of continuous epidural administration of bupivacaine through a catheter in pigs. , 1986, European journal of anaesthesiology.

[20]  R. E. Kane Neurologic Deficits following Epidural or Spinal Anesthesia , 1981, Anesthesia and analgesia.

[21]  J. Bernat Intraspinal steroid therapy , 1981, Neurology.

[22]  G. Lundborg,et al.  Local Anesthetics: Importance of Mode of Application, Concentration and Adrenaline for the Appearance of Nerve Lesions: An Experimental Study of Axonal Degeneration and Barrier Damage after Intrafascicular Injection or Topical Application of Bupivacaine (Marcah®) , 1979, Acta anaesthesiologica Scandinavica.

[23]  M. W. Galbert,et al.  Epidural Injection of Autologous Blood For Postlumbar‐Puncture Headache: II. Additional Clinical Experiences and Laboratory Investigation , 1972, Anesthesia and analgesia.

[24]  I. J. Jackson,et al.  Aseptic hemogenic meningitis; an experimental study of aseptic meningeal reactions due to blood and its breakdown products. , 1949, Archives of neurology and psychiatry.