Order out of chaos: assembly of ligand binding sites in heparan sulfate.
暂无分享,去创建一个
[1] R. Dwek,et al. Concepts and principles of O-linked glycosylation. , 1998, Critical reviews in biochemistry and molecular biology.
[2] A. D. de Agostini,et al. Anticoagulant heparan sulfate proteoglycans expression in the rat ovary peaks in preovulatory granulosa cells. , 2001, Glycobiology.
[3] C. Hirschberg,et al. A single protein catalyzes both N-deacetylation and N-sulfation during the biosynthesis of heparan sulfate. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[4] R. Beddington,et al. The Molecular Phenotype of Heparan Sulfate in theHs2st −/− Mutant Mouse* , 2001, The Journal of Biological Chemistry.
[5] V. Hascall,et al. Proteoglycan core protein families. , 1986, Annual review of biochemistry.
[6] J. Turnbull,et al. Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains. , 1994, The Journal of biological chemistry.
[7] U. Lindahl,et al. Biosynthesis of heparan sulfate in rat liver. Characterization of polysaccharides obtained with intact cells and with a cell-free system. , 1982, The Journal of biological chemistry.
[8] F. Hanisch,et al. O-Glycosylation of the Mucin Type , 2001, Biological chemistry.
[9] C. Hirschberg,et al. Molecular cloning and expression of a glycosaminoglycan N-acetylglucosaminyl N-deacetylase/N-sulfotransferase from a heparin-producing cell line. , 1994, The Journal of biological chemistry.
[10] L. Kjellén,et al. Expression of the mouse mastocytoma glucosaminyl N-deacetylase/ N-sulfotransferase in human kidney 293 cells results in increased N-sulfation of heparan sulfate. , 1996, Biochemistry.
[11] A. Lander,et al. Differential binding of chemokines to glycosaminoglycan subpopulations , 1994, Current Biology.
[12] E. Guillén,et al. Mammalian Golgi apparatus UDP-N-acetylglucosamine transporter: molecular cloning by phenotypic correction of a yeast mutant. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[13] K. Biemann,et al. Sequencing of 3-O sulfate containing heparin decasaccharides with a partial antithrombin III binding site. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[14] M. Höök,et al. Biosynthesis of heparin. Assay and properties of the microsomal N-acetyl-D-glucosaminyl N-deacetylase. , 1980, The Journal of biological chemistry.
[15] A. Malmström,et al. Biosynthesis of heparin. Assay and properties of the microsomal uronosyl C-5 epimerase. , 1979, The Journal of biological chemistry.
[16] K. Kleesiek,et al. Molecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II. , 2000, Journal of molecular biology.
[17] M. Lovett,et al. The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes , 1996, Nature Genetics.
[18] J. Turnbull,et al. A strategy for rapid sequencing of heparan sulfate and heparin saccharides. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[19] L. Eriksson,et al. Structure of heparan sulphate from human brain, with special regard to Alzheimer's disease. , 1995, The Biochemical journal.
[20] W. Halfter,et al. Agrin: an extracellular matrix heparan sulfate proteoglycan involved in cell interactions and synaptogenesis. , 1996, Perspectives on developmental neurobiology.
[21] Z. Shriver,et al. Direct isolation and sequencing of specific protein-binding glycosaminoglycans , 2001, Nature Medicine.
[22] D. Schlessinger,et al. Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome , 1996, Nature Genetics.
[23] R L Jackson,et al. Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes. , 1991, Physiological reviews.
[24] E. Ruoslahti,et al. Analysis of glycosaminoglycan substitution in decorin by site-directed mutagenesis. , 1990, The Journal of biological chemistry.
[25] C. Kevil,et al. Translational enhancement of FGF-2 by eIF-4 factors, and alternate utilization of CUG and AUG codons for translation initiation. , 1995, Oncogene.
[26] N. Schwartz,et al. Biosynthesis of chondroitin sulfate: interaction between xylosyltransferase and galactosyltransferase. , 1974, Biochemical and biophysical research communications.
[27] U. Lindahl,et al. Domain Structure of Heparan Sulfates from Bovine Organs* , 1996, The Journal of Biological Chemistry.
[28] G. Barsh,et al. Transgenic Expression of Syndecan-1 Uncovers a Physiological Control of Feeding Behavior by Syndecan-3 , 2001, Cell.
[29] S. Selleck,et al. Structural analysis of glycosaminoglycans in animals bearing mutations in sugarless, sulfateless, and tout-velu. Drosophila homologues of vertebrate genes encoding glycosaminoglycan biosynthetic enzymes. , 2000, The Journal of biological chemistry.
[30] J. Turnbull,et al. Molecular organization of the interferon gamma-binding domain in heparan sulphate. , 1995, The Biochemical journal.
[31] M. Salmivirta,et al. Sequence analysis of heparan sulphate and heparin oligosaccharides. , 1999, The Biochemical journal.
[32] R. Midura,et al. Structural analysis of the linkage region oligosaccharides and unsaturated disaccharides from chondroitin sulfate using CarboPac PA1. , 1992, The Journal of biological chemistry.
[33] C. Bandtlow,et al. Proteoglycans in the developing brain: new conceptual insights for old proteins. , 2000, Physiological reviews.
[34] D. Beeler,et al. 6-O-Sulfotransferase-1 Represents a Critical Enzyme in the Anticoagulant Heparan Sulfate Biosynthetic Pathway* , 2001, The Journal of Biological Chemistry.
[35] M. Schnölzer,et al. First Isolation of Human UDP-d-Xylose: Proteoglycan Core Protein β-d-Xylosyltransferase Secreted from Cultured JAR Choriocarcinoma Cells* , 2001, The Journal of Biological Chemistry.
[36] S. Oka,et al. Molecular cloning and expression of a second glucuronyltransferase involved in the biosynthesis of the HNK-1 carbohydrate epitope. , 1999, Biochemical and biophysical research communications.
[37] M. Bernfield,et al. Heparan sulfate and chondroitin sulfate proteoglycans inhibit E‐selectin binding to endothelial cells , 2001, Journal of cellular biochemistry.
[38] M. Salmivirta,et al. Age-dependent Modulation of Heparan Sulfate Structure and Function* , 1998, The Journal of Biological Chemistry.
[39] R. Rosenberg,et al. Cell mutants defective in synthesizing a heparan sulfate proteoglycan with regions of defined monosaccharide sequence. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[40] U. Lindahl,et al. Biosynthesis of heparin. The D-glucuronosyl- and N-acetyl-D-glucosaminyltransferase reactions and their relation to polymer modification. , 1992, The Biochemical journal.
[41] Nobuyuki Itoh,et al. Fibroblast growth factors , 2001, Genome Biology.
[42] L. Fransson,et al. Structure of the heparan sulfate-protein linkage region. Demonstration of the sequence galactosyl-galactosyl-xylose-2-phosphate. , 1985, The Journal of biological chemistry.
[43] R. Mulligan,et al. Pathway-specific regulation of the synthesis of anticoagulantly active heparan sulfate. , 1994, The Journal of biological chemistry.
[44] M. Wagner,et al. Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1) , 1995, Nature Genetics.
[45] N. Schwartz,et al. Topography of glycosylation and UDP-xylose production. , 1993, The Journal of biological chemistry.
[46] P. Berninsone,et al. Heparan sulfate/heparin N-deacetylase/N-sulfotransferase. The N-sulfotransferase activity domain is at the carboxyl half of the holoenzyme. , 1998, The Journal of biological chemistry.
[47] R. Pope,et al. Analysis of heparan sulfate oligosaccharides by nano-electrospray ionization mass spectrometry. , 2001, Glycobiology.
[48] K. Yoshida,et al. Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase-3A SulfatesN-Unsubstituted Glucosamine Residues* , 1999, The Journal of Biological Chemistry.
[49] J. J. Schwartz,et al. The Retinoic Acid and cAMP-dependent Up-regulation of 3-O-Sulfotransferase-1 Leads to a Dramatic Augmentation of Anticoagulantly Active Heparan Sulfate Biosynthesis in F9 Embryonal Carcinoma Cells* , 1998, The Journal of Biological Chemistry.
[50] L. Kjellén,et al. Regulated Diversity of Heparan Sulfate* , 1998, The Journal of Biological Chemistry.
[51] J. Filmus,et al. Glypicans in growth control and cancer. , 2001, Glycobiology.
[52] S. Pérez,et al. Experimental proof for the structure of a thrombin-inhibiting heparin molecule. , 2001, Chemistry.
[53] N. Perrimon,et al. Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events , 2001, Nature Cell Biology.
[54] L. Kjellén,et al. Biosynthesis of heparin. Relationship between the polymerization and sulphation processes. , 1989, The Biochemical journal.
[55] M. Krasnow,et al. Genetic control of branching morphogenesis. , 1999, Science.
[56] J. Hassell,et al. Identification of Sites in Domain I of Perlecan That Regulate Heparan Sulfate Synthesis* , 1997, The Journal of Biological Chemistry.
[57] H. Kitagawa,et al. The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis , 2000, EMBO reports.
[58] T. A. Fritz,et al. Partial purification and substrate specificity of heparan sulfate alpha-N-acetylglucosaminyltransferase I: synthesis, NMR spectroscopic characterization and in vitro assays of two aryl tetrasaccharides. , 1997, Glycobiology.
[59] M. Porcionatto,et al. Structure of heparan sulfate: identification of variable and constant oligosaccharide domains in eight heparan sulfates of different origins. , 1998, Cellular and molecular biology.
[60] J. Esko,et al. An Animal Cell Mutant Defective in Heparan Sulfate Hexuronic Acid 2-O-Sulfation* , 1996, The Journal of Biological Chemistry.
[61] J. Stow,et al. Localization of human heparan glucosaminyl N-deacetylase/N-sulphotransferase to the trans-Golgi network. , 1997, The Biochemical journal.
[62] L. Kjellén,et al. Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns. , 2000, Biochemistry.
[63] R. Vivès,et al. Regulation of FGF-1 mitogenic activity by heparan sulfate oligosaccharides is dependent on specific structural features: differential requirements for the modulation of FGF-1 and FGF-2. , 2000, Glycobiology.
[64] H. Freeze,et al. A Novel Method to Co-localize Glycosaminoglycan-Core Oligosaccharide Glycosyltransferases in Rat Liver Golgi , 1995, The Journal of Biological Chemistry.
[65] J. Esko,et al. Amino acid determinants that drive heparan sulfate assembly in a proteoglycan. , 1994, The Journal of biological chemistry.
[66] J. Funderburgh. MINI REVIEW Keratan sulfate: structure, biosynthesis, and function , 2000 .
[67] J. Hirsh,et al. Heparin Binding Proteins Contribution to Heparin Rebound After Cardiopulmonary Bypass , 1993, Circulation.
[68] H. Nakato,et al. Drosophila Heparan Sulfate 6-O-Sulfotransferase (dHS6ST) Gene , 2001, The Journal of Biological Chemistry.
[69] A. Varki,et al. Calcium-dependent heparin-like ligands for L-selectin in nonlymphoid endothelial cells. , 1993, Science.
[70] K. Yoshida,et al. Human Homolog of Caenorhabditis elegans sqv-3 Gene Is Galactosyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans* , 1999, The Journal of Biological Chemistry.
[71] L. Kjellén,et al. Proteoglycans: structures and interactions. , 1991, Annual review of biochemistry.
[72] M. Höök,et al. Biosynthesis of heparin. Studies on the microsomal sulfation process. , 1975, The Journal of biological chemistry.
[73] M. Lyon,et al. Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants. , 1994, The Journal of biological chemistry.
[74] T. Darden,et al. Heparan/Chondroitin Sulfate Biosynthesis , 2000, The Journal of Biological Chemistry.
[75] R. Iozzo. The Biology of the Small Leucine-rich Proteoglycans , 1999, The Journal of Biological Chemistry.
[76] L. Rosenfeld,et al. Location of specific oligosaccharides in heparin in terms of their distance from the protein linkage region in the native proteoglycan. , 1988, The Journal of biological chemistry.
[77] P. Robbins,et al. Transporters of nucleotide sugars, ATP, and nucleotide sulfate in the endoplasmic reticulum and Golgi apparatus. , 1998, Annual review of biochemistry.
[78] J. Silbert,et al. Effects of brefeldin A on the localization of chondroitin sulfate-synthesizing enzymes. Activities in subfractions of the Golgi from chick embryo epiphyseal cartilage. , 1992, The Journal of biological chemistry.
[79] J. Marsh,et al. Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila. , 1997, Development.
[80] D. Stainier,et al. UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish. , 2001, Science.
[81] J. J. Schwartz,et al. Molecular Cloning and Expression of Mouse and Human cDNAs Encoding Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase* , 1997, The Journal of Biological Chemistry.
[82] I. Fuki,et al. Cell-surface heparan sulfate proteoglycans: dynamic molecules mediating ligand catabolism , 1997, Current opinion in lipidology.
[83] J. J. Schwartz,et al. The Effect of Precursor Structures on the Action of Glucosaminyl 3-O-Sulfotransferase-1 and the Biosynthesis of Anticoagulant Heparan Sulfate* , 2001, The Journal of Biological Chemistry.
[84] G. Palade,et al. Sulfated compounds in the zymogen granules of the guinea pig pancreas , 1978, The Journal of cell biology.
[85] P. Spear,et al. Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry. , 2001, The Journal of clinical investigation.
[86] S. Stringer,et al. Specific Binding of the Chemokine Platelet Factor 4 to Heparan Sulfate* , 1997, The Journal of Biological Chemistry.
[87] C. McCormick,et al. The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[88] J. Massagué,et al. A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[89] D. Feingold,et al. Biosynthesis of heparin. Loss of C-5 hydrogen during conversion of D-glucuronic to L-iduronic acid residues. , 1976, Biochemical and biophysical research communications.
[90] P. de Waard,et al. Structural studies on sulfated oligosaccharides derived from the carbohydrate-protein linkage region of chondroitin 6-sulfate proteoglycans of shark cartilage. I. Six compounds containing 0 or 1 sulfate and/or phosphate residues. , 1992, The Journal of biological chemistry.
[91] E. Quentin,et al. A genetic defect in the biosynthesis of dermatan sulfate proteoglycan: galactosyltransferase I deficiency in fibroblasts from a patient with a progeroid syndrome. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[92] M. Gordon,et al. IL-12 is a heparin-binding cytokine. , 1999, Journal of immunology.
[93] C. McCormick,et al. The link between heparan sulfate and hereditary bone disease: finding a function for the EXT family of putative tumor suppressor proteins. , 2001, The Journal of clinical investigation.
[94] H. Kitagawa,et al. Molecular Cloning and Expression of Glucuronyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans* , 1998, The Journal of Biological Chemistry.
[95] Y. Okumura,et al. The phosphorylated and/or sulfated structure of the carbohydrate-protein-linkage region isolated from chondroitin sulfate in the hybrid proteoglycans of Engelbreth-Holm-Swarm mouse tumor. , 1992, European journal of biochemistry.
[96] S. Jhanwar,et al. Expression of GPC3, an X-linked recessive overgrowth gene, is silenced in malignant mesothelioma , 2000, Oncogene.
[97] M. Salmivirta,et al. Binding of Heparin/Heparan Sulfate to Fibroblast Growth Factor Receptor 4* , 2001, The Journal of Biological Chemistry.
[98] H. Piwnica-Worms,et al. The G2 DNA Damage Checkpoint Delays Expression of Genes Encoding Mitotic Regulators* , 2001, The Journal of Biological Chemistry.
[99] D. Feingold,et al. Biosynthesis of heparin. Substrate specificity of heparosan N-sulfate D-glucuronosyl 5-epimerase. , 1984, The Journal of biological chemistry.
[100] H. Ertesvåg,et al. Hexuronyl C5-epimerases in alginate and glycosaminoglycan biosynthesis. , 2001, Biochimie.
[101] L. Gotow,et al. Oligosaccharide Sequence of Human Breast Cancer Cell Heparan Sulfate with High Affinity for Laminin* , 1998, The Journal of Biological Chemistry.
[102] R. Pettersson,et al. Characterization of fibroblast growth factor 1 binding heparan sulfate domain. , 1999, Glycobiology.
[103] L. Pedersen,et al. Crystal Structure of the Sulfotransferase Domain of Human Heparan Sulfate N-Deacetylase/ N-Sulfotransferase 1* , 1999, The Journal of Biological Chemistry.
[104] H. Yoshida,et al. Structural differences and the presence of unsubstituted amino groups in heparan sulphates from different tissues and species. , 1997, The Biochemical journal.
[105] S. Hemmerich,et al. MINI REVIEW Carbohydrate sulfotransferases in lymphocyte homing , 2000 .
[106] H. Horvitz,et al. Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[107] Z. Shriver,et al. Sequencing complex polysaccharides. , 1999, Science.
[108] D. Martindale,et al. The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate , 1998, Nature Genetics.
[109] R. U. Margolis,et al. Disaccharide Composition of Heparan Sulfates: Brain, Nervous Tissue Storage Organelles, Kidney, and Lung , 1994, Journal of neurochemistry.
[110] J. Spring,et al. Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans. , 1992, Annual review of cell biology.
[111] H. Kitagawa,et al. Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[112] D. Spillmann,et al. Characterization of Heparin and Heparan Sulfate Domains Binding to the Long Splice Variant of Platelet-derived Growth Factor A Chain* , 1997, The Journal of Biological Chemistry.
[113] C. McKerlie,et al. Glypican-3–Deficient Mice Exhibit Developmental Overgrowth and Some of the Abnormalities Typical of Simpson-Golabi-Behmel Syndrome , 1999, The Journal of cell biology.
[114] U. Lindahl,et al. Biosynthesis of heparin. Enzymatic sulfation of pentasaccharides. , 1991, The Journal of biological chemistry.
[115] B. Olwin,et al. Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4. , 1993, The Journal of biological chemistry.
[116] E. Buddecke,et al. Two N-acetylgalactosaminyltransferase are involved in the biosynthesis of chondroitin sulfate. , 1985, European journal of biochemistry.
[117] J. Silbert,et al. Biosynthesis of chondroitin sulfate. Organization of sulfation. , 1989, The Journal of biological chemistry.
[118] J. Esko,et al. Chinese Hamster Ovary Cell Mutants Defective in Glycosaminoglycan Assembly and Glucuronosyltransferase I* , 1999, The Journal of Biological Chemistry.
[119] P. Seeberger,et al. Portable sulphotransferase domain determines sequence specificity of heparan sulphate 3-O-sulphotransferases. , 2001, The Biochemical journal.
[120] M. Petitou,et al. Biosynthesis of heparin. O-sulfation of the antithrombin-binding region. , 1988, The Journal of biological chemistry.
[121] M. Hollingsworth,et al. A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family. , 1998, The Journal of biological chemistry.
[122] N. Schwartz,et al. Xylosylation is an endoplasmic reticulum to Golgi event. , 1993, The Journal of biological chemistry.
[123] M. Höök,et al. Glycosaminoglycans and their binding to biological macromolecules. , 1978, Annual review of biochemistry.
[124] L. Rodén,et al. Biosynthesis of heparin. Transfer of N-acetylglucosamine to heparan sulfate oligosaccharides. , 1981, The Journal of biological chemistry.
[125] J. Esko,et al. Sulfate transport-deficient mutants of Chinese hamster ovary cells. Sulfation of glycosaminoglycans dependent on cysteine. , 1986, The Journal of biological chemistry.
[126] M. Salmivirta,et al. Selectively Desulfated Heparin Inhibits Fibroblast Growth Factor-induced Mitogenicity and Angiogenesis* , 2000, The Journal of Biological Chemistry.
[127] D. Feingold,et al. Biosynthesis of heparin. Hydrogen exchange at carbon 5 of the glucuronosyl residues. , 1980, Biochemistry.
[128] A. Friedl,et al. Differential ability of heparan sulfate proteoglycans to assemble the fibroblast growth factor receptor complex in situ , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[129] J. Schlessinger,et al. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. , 2000, Molecular cell.
[130] I. Goldberg,et al. Oligosaccharide sequences of endothelial cell surface heparan sulfate proteoglycan with affinity for lipoprotein lipase. , 1994, The Journal of biological chemistry.
[131] J. Esko,et al. Cloning, Golgi Localization, and Enzyme Activity of the Full-length Heparin/Heparan Sulfate-Glucuronic Acid C5-epimerase* , 2001, The Journal of Biological Chemistry.
[132] K. Kimata,et al. Substrate specificity of the heparan sulfate hexuronic acid 2-O-sulfotransferase. , 2001, Biochemistry.
[133] M. Salmivirta,et al. Structural diversity of N-sulfated heparan sulfate domains: distinct modes of glucuronyl C5 epimerization, iduronic acid 2-O-sulfation, and glucosamine 6-O-sulfation. , 2000, Biochemistry.
[134] J. Herbert,et al. Synthesis of thrombin-inhibiting heparin mimetics without side effects , 1999, Nature.
[135] M. Filla,et al. Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition , 2001, The Journal of cell biology.
[136] J. Esko,et al. Inhibition of chondroitin and heparan sulfate biosynthesis in Chinese hamster ovary cell mutants defective in galactosyltransferase I. , 1987, The Journal of biological chemistry.
[137] R. Iozzo. Matrix proteoglycans: from molecular design to cellular function. , 1998, Annual review of biochemistry.
[138] R. Weksberg,et al. Developmental Biology: Frontiers for Clinical Genetics: Overgrowth syndromes and genomie imprinting: from mouse to man , 1998 .
[139] S. Selleck,et al. The division abnormally delayed (dally) gene: a putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila. , 1995, Development.
[140] A. Sharpe,et al. Heparin is essential for the storage of specific granule proteases in mast cells , 1999, Nature.
[141] Zheng Wei,et al. Functional Analysis of Conserved Cysteines in Heparan SulfateN-Deacetylase-N-sulfotransferases* , 1999, The Journal of Biological Chemistry.
[142] David F. Burke,et al. Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin , 2000, Nature.
[143] J. Esko,et al. Undersulfated heparan sulfate in a Chinese hamster ovary cell mutant defective in heparan sulfate N-sulfotransferase. , 1989, The Journal of biological chemistry.
[144] L. Pedersen,et al. A role of Lys614 in the sulfotransferase activity of human heparan sulfate N‐deacetylase/N‐sulfotransferase , 1998, FEBS letters.
[145] G. Hu,et al. Targeted disruption of NDST‐1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice , 2000, FEBS letters.
[146] D. Spillmann,et al. Glycosaminoglycan-protein interactions: a question of specificity , 1994 .
[147] H. Kitagawa,et al. Demonstration of the Immature Glycosaminoglycan Tetrasaccharide Sequence GlcAβ1–3Galβ1–3Galβ1–4Xyl on Recombinant Soluble Human α-Thrombomodulin , 1998, The Journal of Biological Chemistry.
[148] J. Esko,et al. Formation of HNK-1 Determinants and the Glycosaminoglycan Tetrasaccharide Linkage Region by UDP-GlcUA:Galactose β1,3-Glucuronosyltransferases* , 1999, The Journal of Biological Chemistry.
[149] M. Matzuk,et al. Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. , 2000, Developmental biology.
[150] L. Kjellén,et al. Cell-Surface Glycosaminoglycans , 1984 .
[151] U. Lindahl,et al. Mode of interaction between platelet factor 4 and heparin. , 1993, Glycobiology.
[152] S. Hubbard,et al. Structural Basis for FGF Receptor Dimerization and Activation , 1999, Cell.
[153] J. Karlinsky,et al. cDNA cloning, genomic organization and chromosomal localization of human heparan glucosaminyl N-deacetylase/N-sulphotransferase-2. , 1998, The Biochemical journal.
[154] Jian Liu,et al. Purification of Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase* , 1996, The Journal of Biological Chemistry.
[155] Eric S. Lander,et al. The diastrophic dysplasia gene encodes a novel sulfate transporter: Positional cloning by fine-structure linkage disequilibrium mapping , 1994, Cell.
[156] R. Rosenberg,et al. Anticoagulant Heparan Sulfate Precursor Structures in F9 Embryonal Carcinoma Cells* , 1999, The Journal of Biological Chemistry.
[157] Christine M. Williams. Editorial Comment: Nutrition , 1997 .
[158] Joseph Schlessinger,et al. Crystal Structures of Two FGF-FGFR Complexes Reveal the Determinants of Ligand-Receptor Specificity , 2000, Cell.
[159] T. Doering,et al. Functional cloning and characterization of a UDP- glucuronic acid decarboxylase: The pathogenic fungus Cryptococcus neoformans elucidates UDP-xylose synthesis , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[160] A. Woods,et al. Syndecans: synergistic activators of cell adhesion. , 1998, Trends in cell biology.
[161] M. Lyon,et al. Liver heparan sulfate structure. A novel molecular design. , 1994, The Journal of biological chemistry.
[162] G. Giménez-Gallego,et al. Sequence Analysis of Heparan Sulfate Epitopes with Graded Affinities for Fibroblast Growth Factors 1 and 2* , 2001, The Journal of Biological Chemistry.
[163] U. Lindahl,et al. Biosynthesis of heparin/heparan sulfate. Purification of the D-glucuronyl C-5 epimerase from bovine liver. , 1994, The Journal of biological chemistry.
[164] M. Warman,et al. A member of a family of sulfate-activating enzymes causes murine brachymorphism. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[165] E. Kempner,et al. A monomeric protein in the Golgi membrane catalyzes both N-deacetylation and N-sulfation of heparan sulfate. , 1994, The Journal of biological chemistry.
[166] S. Selleck,et al. The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila , 1999, Nature.
[167] J. Silbert. Biosynthesis of heparin. IV. N-Deacetylation of a precursor glycosaminoglycan. , 1967, The Journal of biological chemistry.
[168] D. Schlessinger,et al. Frequent silencing of the GPC3 gene in ovarian cancer cell lines. , 1999, Cancer research.
[169] J. Esko,et al. Etiological point mutations in the hereditary multiple exostoses gene EXT1: a functional analysis of heparan sulfate polymerase activity. , 2001, American journal of human genetics.
[170] L. Kjellén,et al. Identification and Expression in Mouse of Two Heparan Sulfate Glucosaminyl N-Deacetylase/N-Sulfotransferase Genes* , 1998, The Journal of Biological Chemistry.
[171] K. Holme,et al. Identification of structural features of heparin required for inhibition of herpes simplex virus type 1 binding. , 1995, Virology.
[172] Expression of heparan sulphate L-iduronyl 2-O-sulphotransferase in human kidney 293 cells results in increased D-glucuronyl 2-O-sulphation. , 2000, The Biochemical journal.
[173] A. Lander,et al. Mechanisms Underlying Preferential Assembly of Heparan Sulfate on Glypican-1* , 2001, The Journal of Biological Chemistry.
[174] A. Varki,et al. Endothelial Heparan Sulfate Proteoglycans That Bind to L-Selectin Have Glucosamine Residues with Unsubstituted Amino Groups (*) , 1995, The Journal of Biological Chemistry.
[175] H. Nader,et al. Structural differences of heparan sulfates according to the tissue and species of origin. , 1983, Biochemical and biophysical research communications.
[176] J. Turnbull,et al. Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate. , 1992, The Journal of biological chemistry.
[177] S. Selleck,et al. Structural Analysis of Glycosaminoglycans inDrosophila and Caenorhabditis elegans and Demonstration That tout-velu, a Drosophila Gene Related to EXT Tumor Suppressors, Affects Heparan Sulfate in Vivo * , 2000, The Journal of Biological Chemistry.
[178] W. A. Johnson,et al. Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling. , 1997, Development.
[179] H. Horvitz,et al. SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP-N- acetylgalactosamine, and UDP-galactose , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[180] K. Yoshida,et al. The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the TargetedN-Sulfoglucosamine* , 2000, The Journal of Biological Chemistry.
[181] D. Prockop,et al. Location of xylosyltransferase in the cisternae of the rough endoplasmic reticulum of embryonic cartilage cells. , 1984, Connective tissue research.
[182] W. Hendrickson,et al. Structural interactions of fibroblast growth factor receptor with its ligands. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[183] M. Bernfield,et al. Structural Characterization of Heparan Sulfate and Chondroitin Sulfate of Syndecan-1 Purified from Normal Murine Mammary Gland Epithelial Cells , 2001, The Journal of Biological Chemistry.
[184] S. Selleck,et al. sqv-3, -7, and -8, a set of genes affecting morphogenesis in Caenorhabditis elegans, encode enzymes required for glycosaminoglycan biosynthesis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[185] J. Esko,et al. Influence of core protein sequence on glycosaminoglycan assembly. , 1996, Current opinion in structural biology.
[186] L. Toma,et al. The Putative Heparin-specific N-AcetylglucosaminylN-Deacetylase/N-Sulfotransferase Also Occurs in Non-heparin-producing Cells* , 1998, The Journal of Biological Chemistry.
[187] E. Bennett,et al. Cloning and Expression of a Proteoglycan UDP-Galactose:β-Xylose β1,4-Galactosyltransferase I , 1999, The Journal of Biological Chemistry.
[188] N. Perrimon,et al. Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. , 1999, Development.
[189] R. Beddington,et al. Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. , 1998, Genes & development.
[190] A. Edge,et al. Characterization of novel sequences containing 3-O-sulfated glucosamine in glomerular basement membrane heparan sulfate and localization of sulfated disaccharides to a peripheral domain. , 1990, The Journal of biological chemistry.
[191] J. Esko,et al. Molecular Cloning and Expression of a Third Member of the Heparan Sulfate/Heparin GlcNAcN-Deacetylase/ N-Sulfotransferase Family* , 1999, The Journal of Biological Chemistry.
[192] A. M. Lawson,et al. 10E4 Antigen of Scrapie Lesions Contains an Unusual Nonsulfated Heparan Motif* , 2001, The Journal of Biological Chemistry.
[193] R. Rosenberg,et al. Characterization of a cell mutant specifically defective in the synthesis of anticoagulantly active heparan sulfate. , 1994, The Journal of biological chemistry.
[194] S. Selleck,et al. Regulation of dally, an integral membrane proteoglycan, and its function during adult sensory organ formation of Drosophila. , 2001, Developmental biology.
[195] A. V. van Kessel,et al. A Family of Human β4-Galactosyltransferases , 1997, The Journal of Biological Chemistry.
[196] J. Esko,et al. Location of the glucuronosyltransferase domain in the heparan sulfate copolymerase EXT1 by analysis of Chinese hamster ovary cell mutants. , 2000, The Journal of biological chemistry.
[197] J. Esko,et al. Enzyme interactions in heparan sulfate biosynthesis: Uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[198] N. Rosenblum,et al. Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis. , 2001, Developmental biology.
[199] L. Pedersen,et al. Structure and function of sulfotransferases. , 2001, Archives of biochemistry and biophysics.
[200] R. Timpl,et al. Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin , 1999, The EMBO journal.
[201] M. Höök,et al. Biosynthesis of heparin. Concerted action of early polymer-modification reactions. , 1982, The Journal of biological chemistry.
[202] K. Kimata,et al. Characterization of Heparan Sulfate Oligosaccharides That Bind to Hepatocyte Growth Factor (*) , 1995, The Journal of Biological Chemistry.
[203] M. Lyon,et al. Highly Sensitive Sequencing of the Sulfated Domains of Heparan Sulfate* , 1999, The Journal of Biological Chemistry.
[204] O Habuchi,et al. Diversity and functions of glycosaminoglycan sulfotransferases. , 2000, Biochimica et biophysica acta.
[205] T. Hennet,et al. Biosynthesis of the Linkage Region of Glycosaminoglycans , 2001, The Journal of Biological Chemistry.
[206] N. Perrimon,et al. Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion , 1998, Nature.
[207] A. Imberty,et al. Structure/function studies of glycosyltransferases. , 1999, Current opinion in structural biology.
[208] S. Selleck,et al. Glypicans: proteoglycans with a surprise. , 2001, The Journal of clinical investigation.
[209] N. Perrimon,et al. Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. , 1999, Molecular cell.
[210] R. Eisenberg,et al. A Novel Role for 3-O-Sulfated Heparan Sulfate in Herpes Simplex Virus 1 Entry , 1999, Cell.
[211] N. Razi,et al. Biosynthesis of heparin/heparan sulfate. The D-glucosaminyl 3-O- sulfotransferase reaction: target and inhibitor saccharides , 1995, The Journal of Biological Chemistry.
[212] I. Pettersson,et al. Biosynthesis of heparin. Purification of a 110-kDa mouse mastocytoma protein required for both glucosaminyl N-deacetylation and N-sulfation. , 1991, The Journal of biological chemistry.
[213] J. Westley,et al. Biosynthesis of heparin/heparan sulfate: kinetic studies of the glucuronyl C5-epimerase with N-sulfated derivatives of the Escherichia coli K5 capsular polysaccharide as substrates. , 2000, Glycobiology.
[214] A. Oldberg,et al. Biosynthesis of decorin and glypican. , 2000, Matrix biology : journal of the International Society for Matrix Biology.
[215] J. Esko,et al. Molecular diversity of heparan sulfate. , 2001, The Journal of clinical investigation.
[216] H. Ogawa,et al. Glycosaminoglycan Binding Properties of Annexin IV, V, and VI* , 1998, The Journal of Biological Chemistry.
[217] U. Lindahl,et al. Biosynthesis of heparin/heparan sulphate: mechanism of epimerization of glucuronyl C-5. , 2000, The Biochemical journal.
[218] K. Kuettner,et al. Post-translational events in proteoglycan synthesis: kinetics of synthesis of chondroitin sulfate and oligosaccharides on the core protein. , 1986, Archives of biochemistry and biophysics.
[219] J. J. Schwartz,et al. Expression of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase Isoforms Reveals Novel Substrate Specificities* , 1999, The Journal of Biological Chemistry.
[220] H. Kitagawa,et al. The Tumor Suppressor EXT-like Gene EXTL2 Encodes an α1, 4-N-Acetylhexosaminyltransferase That TransfersN-Acetylgalactosamine and N-Acetylglucosamine to the Common Glycosaminoglycan-Protein Linkage Region , 1999, The Journal of Biological Chemistry.
[221] J. Esko,et al. Repetitive Ser-Gly Sequences Enhance Heparan Sulfate Assembly in Proteoglycans (*) , 1995, The Journal of Biological Chemistry.
[222] L. Hellman,et al. Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme , 1999, Nature.
[223] J. van den Born,et al. Presence of N-Unsubstituted Glucosamine Units in Native Heparan Sulfate Revealed by a Monoclonal Antibody (*) , 1995, The Journal of Biological Chemistry.
[224] J. Esko,et al. Sulphated and undersulphated heparan sulphate proteoglycans in a Chinese hamster ovary cell mutant defective in N-sulphotransferase. , 1994, The Biochemical journal.
[225] M. Forster,et al. Conformation and dynamics of heparin and heparan sulfate. , 2000, Glycobiology.
[226] A. Oldberg,et al. Initiation of galactosaminoglycan biosynthesis , 1999 .
[227] D. Spillmann,et al. Structural Requirement of Heparan Sulfate for Interaction with Herpes Simplex Virus Type 1 Virions and Isolated Glycoprotein C* , 1997, The Journal of Biological Chemistry.
[228] U. Lindahl,et al. Glycosaminoglycans and the regulation of blood coagulation. , 1993, The Biochemical journal.
[229] W. Skarnes,et al. glypican-3 controls cellular responses to Bmp4 in limb patterning and skeletal development. , 2000, Developmental biology.
[230] A. Oldberg,et al. Biosynthesis of the proteoglycan decorin--transient 2-phosphorylation of xylose during formation of the trisaccharide linkage region. , 1997, European journal of biochemistry.
[231] N. Copeland,et al. Multiple Isoforms of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase , 1999, The Journal of Biological Chemistry.
[232] T. V. van Kuppevelt,et al. Defective Heparan Sulfate Biosynthesis and Neonatal Lethality in Mice LackingN-Deacetylase/N-Sulfotransferase-1* , 2000, The Journal of Biological Chemistry.
[233] A. Amores,et al. The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension. , 2001, Developmental cell.
[234] H. Kitagawa,et al. Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans. , 2000, Current opinion in structural biology.
[235] M. Jalkanen,et al. Characterization of the d-Glucuronyl C5-epimerase Involved in the Biosynthesis of Heparin and Heparan Sulfate* , 2001, The Journal of Biological Chemistry.
[236] J. J. Schwartz,et al. Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated? , 1997, The Journal of clinical investigation.
[237] M. Götte,et al. Functions of cell surface heparan sulfate proteoglycans. , 1999, Annual review of biochemistry.
[238] D. Spillmann,et al. Defining the Interleukin-8-binding Domain of Heparan Sulfate* , 1998, The Journal of Biological Chemistry.
[239] N. Perrimon,et al. Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling , 1999, Nature.
[240] L. Kjellén,et al. cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin. , 1994, The Journal of biological chemistry.
[241] M. Salmivirta,et al. Heparan sulfate : a piece of information , 2004 .
[242] N. Perrimon,et al. The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. , 1997, Development.
[243] M. Humphries,et al. Elucidation of the Structural Features of Heparan Sulfate Important for Interaction with the Hep-2 Domain of Fibronectin* , 2000, The Journal of Biological Chemistry.
[244] R. Iozzo,et al. The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices. , 1994, The Biochemical journal.
[245] Y. Kozutsumi,et al. Cloning and functional expression of a novel glucuronyltransferase involved in the biosynthesis of the carbohydrate epitope HNK-1. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[246] S. Selleck,et al. dally, a Drosophila glypican, controls cellular responses to the TGF-beta-related morphogen, Dpp. , 1997, Development.
[247] S. Goto,et al. UDP–sugar transporter implicated in glycosylation and processing of Notch , 2001, Nature Cell Biology.
[248] R. Iozzo. Presence of unsulfated heparan chains on the heparan sulfate proteoglycan of human colon carcinoma cells. Implications for heparan sulfate proteoglycan biosynthesis. , 1989, The Journal of biological chemistry.
[249] T. A. Fritz,et al. Two N-acetylglucosaminyltransferases catalyze the biosynthesis of heparan sulfate. , 1994, The Journal of biological chemistry.
[250] J. Esko,et al. Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4. , 2001, The Journal of biological chemistry.