Desensitization of transient receptor potential vanilloid type-1 (TRPV1) channel as promising therapy of irritable bowel syndrome: characterization of the action of palvanil in the mouse gastrointestinal tract
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J. Fichna | M. Storr | V. Di Marzo | A. Wasilewski | M. Zielińska | J. Włodarczyk | A. Szymaszkiewicz
[1] G. Boeckxstaens,et al. Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS , 2017, Scientific Reports.
[2] J. Fichna,et al. Methyl-orvinol—Dual activity opioid receptor ligand inhibits gastrointestinal transit and alleviates abdominal pain in the mouse models mimicking diarrhea-predominant irritable bowel syndrome , 2017, Pharmacological reports : PR.
[3] M. Neurath,et al. Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain , 2016, Scientific Reports.
[4] W. Krajewska,et al. Orally administered novel cyclic pentapeptide P‐317 alleviates symptoms of diarrhoea‐predominant irritable bowel syndrome , 2015, The Journal of pharmacy and pharmacology.
[5] J. Fichna,et al. Novel mixed NOP/MOP agonist BU08070 alleviates pain and inhibits gastrointestinal motility in mouse models mimicking diarrhea-predominant irritable bowel syndrome symptoms. , 2014, European journal of pharmacology.
[6] G. Boeckxstaens,et al. Sensitivity Testing in Irritable Bowel Syndrome With Rectal Capsaicin Stimulations: Role of TRPV1 Upregulation and Sensitization in Visceral Hypersensitivity? , 2014, The American Journal of Gastroenterology.
[7] D. Julius. TRP channels and pain. , 2013, Annual review of cell and developmental biology.
[8] C. Weber,et al. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. , 2013, American journal of physiology. Gastrointestinal and liver physiology.
[9] V. Di Marzo,et al. Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature. , 2012, Pharmacological research.
[10] R. Rahmati. The transient receptor potential vanilloid receptor 1, TRPV1 (VR1) inhibits peristalsis in the mouse jejunum. , 2012, Archives of Iranian medicine.
[11] P. Holzer. Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system , 2011, Pharmacology & therapeutics.
[12] M. Bortolotti,et al. Effect of Red Pepper on Symptoms of Irritable Bowel Syndrome: Preliminary Study , 2011, Digestive Diseases and Sciences.
[13] F. Piscitelli,et al. N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. , 2011, Pharmacological research.
[14] E. Sher,et al. Pungency of TRPV1 agonists is directly correlated with kinetics of receptor activation and lipophilicity. , 2010, European journal of pharmacology.
[15] M. Kinouchi,et al. Intracolonic capsaicin stimulates colonic motility and defecation in conscious dogs. , 2010, Surgery.
[16] L. Blackshaw,et al. TRP channels: new targets for visceral pain , 2009, Gut.
[17] A. Janecka,et al. Salvinorin A inhibits colonic transit and neurogenic ion transport in mice by activating κ‐opioid and cannabinoid receptors , 2009, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[18] J. Priestley,et al. Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon. , 2009, American journal of physiology. Gastrointestinal and liver physiology.
[19] S. Gonlachanvit,et al. Effects of chili on postprandial gastrointestinal symptoms in diarrhoea predominant irritable bowel syndrome: evidence for capsaicin‐sensitive visceral nociception hypersensitivity , 2009, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[20] P. Anand,et al. Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain , 2008, Gut.
[21] Kenjiro Matsumoto,et al. Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine. , 2007, European journal of pharmacology.
[22] T. Frieling,et al. Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon. , 2006, Gastroenterology.
[23] N. Hyland,et al. The regulation of veratridine‐stimulated electrogenic ion transport in mouse colon by neuropeptide Y (NPY), Y1 and Y2 receptors , 2005, British journal of pharmacology.
[24] K. Bölcskei,et al. Investigation of the role of TRPV1 receptors in acute and chronic nociceptive processes using gene-deficient mice , 2005, Pain.
[25] P. McIntyre,et al. Cloning and functional characterization of the guinea pig vanilloid receptor 1 , 2002, Neuropharmacology.
[26] I. Sasaki,et al. Intragastric Capsaicin Stimulates Motility of Upper Gut and Proximal Colon via Distinct Pathways in Conscious Dogs , 1999, Digestive Diseases and Sciences.
[27] D. Julius,et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway , 1997, Nature.
[28] C. Maggi,et al. CGRP potentiates excitatory transmission to the circular muscle of guinea-pig colon , 1997, Regulatory Peptides.
[29] J. Teisinger,et al. A "cute" desensitization of TRPV1. , 2011, Current pharmaceutical biotechnology.
[30] A. Zinsmeister,et al. FUNCTIONAL BOWEL DISORDERS , 2007, The American Journal of Gastroenterology.
[31] Stomach , 2006, The American Journal of Gastroenterology.