Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay.
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[1] J. Sullivan,et al. 2,6-Diamino-N-([1-(1-oxotridecyl)-2-piperidinyl]methyl)hexanamide (NPC 15437): A selective inhibitor of protein kinase C , 1991, Agents and Actions.
[2] L. Saraíva,et al. Isoform-selectivity of PKC Inhibitors Acting at the Regulatory and Catalytic Domain of Mammalian PKC-α, -βI, -δ, -η and -ζ , 2003 .
[3] M. Kazanietz,et al. Divergence and complexities in DAG signaling: looking beyond PKC. , 2003, Trends in pharmacological sciences.
[4] E. Sousa,et al. Inhibition of α, βI, δ, η and ζ Protein Kinase C Isoforms by Xanthonolignoids , 2003, Journal of enzyme inhibition and medicinal chemistry.
[5] Y. Nishizuka,et al. Protein kinase C isotypes and their specific functions: prologue. , 2002, Journal of biochemistry.
[6] M. Kazanietz,et al. Protein kinase C isozymes, novel phorbol ester receptors and cancer chemotherapy. , 2001, Current pharmaceutical design.
[7] M. Reilly,et al. Pharmacology of the receptors for the phorbol ester tumor promoters: multiple receptors with different biochemical properties. , 2000, Biochemical pharmacology.
[8] B. Webb,et al. Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis , 2000, British journal of pharmacology.
[9] M. Musashi,et al. The role of protein kinase C isoforms in cell proliferation and apoptosis. , 2000, International journal of hematology.
[10] G. King,et al. Identification of PKC-isoform-specific biological actions using pharmacological approaches. , 2000, Trends in pharmacological sciences.
[11] H. Majewski,et al. The structural requirements for phorbol esters to enhance serotonin and acetylcholine release from rat brain cortex , 1999, British Journal of Pharmacology.
[12] Xiao-ling Guo,et al. Protein Kinase Cδ-dependent Induction of Manganese Superoxide Dismutase Gene Expression by Microtubule-active Anticancer Drugs* , 1998, The Journal of Biological Chemistry.
[13] C. Pears,et al. Isoform specificity of activators and inhibitors of protein kinase C γ and δ , 1997 .
[14] Johann Hofmann,et al. The potential for isoenzyme‐selective modulation of protein kinase C , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[15] D. Fabbro,et al. Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents. , 1997, Biochemical pharmacology.
[16] H. Riedel,et al. Activation of conventional mammalian protein kinase C isoforms expressed in budding yeast modulates the cell doubling time--a potential in vivo screen for protein kinase C activators. , 1996, Cancer Detection and Prevention.
[17] P. Parker,et al. Characterization of phorbol ester binding to protein kinase C isotypes. , 1995, Molecular pharmacology.
[18] H. Riedel,et al. Differential protein kinase C ligand regulation detected in vivo by a phenotypic yeast assay , 1995, Molecular carcinogenesis.
[19] D. Fabbro,et al. Comparison of different tumour promoters and bryostatin 1 on protein kinase C activation and down-regulation in rat renal mesangial cells. , 1994, Biochemical pharmacology.
[20] P. Parker,et al. Expression of mammalian protein kinase C in Schizosaccharomyces pombe: isotype-specific induction of growth arrest, vesicle formation, and endocytosis. , 1994, Molecular biology of the cell.
[21] A. Parissenti,et al. Phorbol ester activation of functional rat protein kinase C β‐1 causes phenotype in yeast , 1993, Journal of cellular biochemistry.
[22] A. Parissenti,et al. Stimulation of calcium uptake in Saccharomyces cerevisiae by bovine protein kinase C alpha. , 1993, The Journal of biological chemistry.
[23] J. Exton,et al. Purification and characterization of the zeta isoform of protein kinase C from bovine kidney. , 1992, The Journal of biological chemistry.
[24] U. Kikkawa,et al. Catalytic properties of yeast protein kinase C: difference between the yeast and mammalian enzymes. , 1992, Journal of Biochemistry (Tokyo).
[25] P. Parker,et al. Effect of phorbol esters on protein kinase C-zeta. , 1992, The Journal of biological chemistry.
[26] J. Sullivan,et al. 2,6-Diamino-N-([1-(1-oxotridecyl)-2-piperidinyl] methyl)hexanamide (NPC 15437): a novel inhibitor of protein kinase C interacting at the regulatory domain. , 1992, Molecular pharmacology.
[27] D. Burns,et al. Protein kinase C contains two phorbol ester binding domains. , 1991, The Journal of biological chemistry.
[28] R. Patch,et al. Substituted 2-(aminomethyl)piperidines: a novel class of selective protein kinase C inhibitors. , 1991, Journal of Medicinal Chemistry.
[29] P. Parker,et al. Activation of the PKC‐isotypes α, β1, γ, δ, and ε by phorbol esters of different biological activities , 1991 .
[30] P. Parker,et al. Phorbol ester activation of the isotypes of protein kinase C from bovine and rat brain. , 1991, Biochemical Society Transactions.
[31] J. Herbert,et al. Chelerythrine is a potent and specific inhibitor of protein kinase C. , 1990, Biochemical and biophysical research communications.
[32] Y. Nishizuka,et al. Protein kinase C in Saccharomyces cerevisiae: comparison with the mammalian enzyme. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[33] K. Koehler,et al. Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[34] Terrence P. Kenakin,et al. A Pharmacologic Analysis of Drug-Receptor Interaction , 1987 .
[35] J. Darbon,et al. Phorbol esters inhibit the proliferation of MCF-7 cells. Possible implication of protein kinase C. , 1986, Biochemical pharmacology.
[36] R. Liskamp,et al. Computer-assisted molecular modeling of tumor promoters: rationale for the activity of phorbol esters, teleocidin B, and aplysiatoxin. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[37] K. Murata,et al. Transformation of intact yeast cells treated with alkali cations , 1983 .
[38] J. Niedel,et al. Phorbol diester receptor copurifies with protein kinase C. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[39] F. Marks,et al. Effects of the phorbol ester 4-O-methyl-12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo: evidence for its uselessness as a negative control compound in studies on the biological effects of phorbol ester tumor promoters. , 1982, Cancer research.
[40] G. Todaro,et al. Specific high affinity cell membrane receptors for biologically active phorbol and ingenol esters , 1980, Nature.
[41] P. Blumberg,et al. Characterization of specific binding of [3H]phorbol 12,13-dibutyrate and [3H]phorbol 12-myristate 13-acetate to mouse brain. , 1980, Cancer research.
[42] T. Slaga,et al. Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion. , 1980, Proceedings of the National Academy of Sciences of the United States of America.
[43] P. Blumberg,et al. Specific binding of phorbol ester tumor promoters to mouse skin , 1980, Cell.