The Role of Non-Phagocytic Cells in Mycobacterial Infections

Tuberculosis is one of the infectious diseases with great impact in the world. It affects mainly to young adults in the productive stage of the life and most of the deaths due to this disease occur in developing countries. All the cities are affected, but 85% of the cases occur in Africa (30%) and Asia (55%). In 2009, the WHO reported 9.4 million new cases, 14 million prevalent cases and 1.7 million deaths; in addition, there is an estimate that one third part of the world-wide population lodges the latent infection. These data place tuberculosis like the third cause of death at world-wide level, after HIV/AIDS and cardiac diseases (WHO, 2010).

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