CENP-E Is a Plus End–Directed Kinetochore Motor Required for Metaphase Chromosome Alignment

[1]  K. Wood,et al.  The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A. , 1996, Journal of cell science.

[2]  E D Salmon,et al.  Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism , 1993, The Journal of cell biology.

[3]  R. Hawley,et al.  Meiotic spindle assembly in Drosophila females: behavior of nonexchange chromosomes and the effects of mutations in the nod kinesin-like protein , 1992, The Journal of cell biology.

[4]  A. Lupas,et al.  Predicting coiled coils from protein sequences , 1991, Science.

[5]  J. McIntosh,et al.  Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro , 1995, The Journal of cell biology.

[6]  B. Berger,et al.  Predicting coiled coils by use of pairwise residue correlations. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[7]  T. Mitchison.  Microtubule dynamics and kinetochore function in mitosis. , 1988, Annual review of cell biology.

[8]  Eric Karsenti,et al.  Spindle Assembly in Xenopus Egg Extracts: Respective Roles of Centrosomes and Microtubule Self-Organization , 1997, The Journal of cell biology.

[9]  G K Lewis,et al.  Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product , 1985, Molecular and cellular biology.

[10]  A. Hyman,et al.  Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy. , 1993, Methods in cell biology.

[11]  R. Zinkowski,et al.  CENP‐E, a novel human centromere‐associated protein required for progression from metaphase to anaphase. , 1991, The EMBO journal.

[12]  A. Bajer.  Functional autonomy of monopolar spindle and evidence for oscillatory movement in mitosis , 1982, The Journal of cell biology.

[13]  A. Riggs,et al.  Genomic Sequencing , 2010 .

[14]  A. Murray,et al.  Cell cycle extracts. , 1991, Methods in cell biology.

[15]  M. Kirschner,et al.  Properties of the kinetochore in vitro. II. Microtubule capture and ATP- dependent translocation , 1985, The Journal of cell biology.

[16]  C. Rieder.  The formation, structure, and composition of the mammalian kinetochore and kinetochore fiber. , 1982, International review of cytology.

[17]  A. Hyman,et al.  Morphogenetic Properties of Microtubules and Mitotic Spindle Assembly , 1996, Cell.

[18]  Ronald D. Vale,et al.  Crystal structure of the kinesin motor domain reveals a structural similarity to myosin , 1996, Nature.

[19]  M. Kirschner,et al.  Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding , 1985, The Journal of cell biology.

[20]  A. Hyman,et al.  Preparation of modified tubulins. , 1991, Methods in enzymology.

[21]  K. Ramyar,et al.  A Complex of NuMA and Cytoplasmic Dynein Is Essential for Mitotic Spindle Assembly , 1996, Cell.

[22]  E. Salmon,et al.  Oscillatory movements of monooriented chromosomes and their position relative to the spindle pole result from the ejection properties of the aster and half-spindle , 1986, The Journal of cell biology.

[23]  E. Salmon,et al.  Microtubule assembly and kinetochore directional instability in vertebrate monopolar spindles: implications for the mechanism of chromosome congression. , 1994, Journal of cell science.

[24]  Roger Cooke,et al.  Crystal structure of the motor domain of the kinesin-related motor ncd , 1996, Nature.

[25]  J. McIntosh,et al.  Tubulin hooks as probes for microtubule polarity: an analysis of the method and an evaluation of data on microtubule polarity in the mitotic spindle , 1984, The Journal of cell biology.

[26]  B. Schaar,et al.  CENP-E is a putative kinetochore motor that accumulates just before mitosis , 1992, Nature.

[27]  E. Salmon,et al.  Oscillating mitotic newt lung cell kinetochores are, on average, under tension and rarely push. , 1996, Journal of cell science.

[28]  J. Moore,et al.  Kinesin proteins: A phylum of motors for microtubule‐based motility , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.

[29]  S Inoué,et al.  1. EARLY HISTORY: THE DYNAMIC EQUILIBRIUM MODEL , 1995 .

[30]  E D Salmon,et al.  Kinetochore motility after severing between sister centromeres using laser microsurgery: evidence that kinetochore directional instability and position is regulated by tension. , 1995, Journal of cell science.

[31]  L. Goldstein,et al.  Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein , 1996, The Journal of cell biology.

[32]  G. Gorbsky,et al.  Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint , 1995, The Journal of cell biology.

[33]  Ronald D Vale,et al.  The Directional Preference of Kinesin Motors Is Specified by an Element outside of the Motor Catalytic Domain , 1997, Cell.

[34]  P. G. Wilson,et al.  Monastral bipolar spindles: implications for dynamic centrosome organization. , 1997, Journal of cell science.

[35]  Eric Karsenti,et al.  Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts , 1996, Nature.

[36]  D. L. Weeks,et al.  Identification and cloning of localized maternal RNAs from xenopus eggs , 1985, Cell.

[37]  A Khodjakov,et al.  Kinetochores moving away from their associated pole do not exert a significant pushing force on the chromosome , 1996, The Journal of cell biology.

[38]  A. Hyman,et al.  Two different microtubule-based motor activities with opposite polarities in kinetochores , 1991, Nature.

[39]  M. Kirschner,et al.  Sites of microtubule assembly and disassembly in the mitotic spindle , 1986, Cell.

[40]  T. Mitchison,et al.  XKCM1: A Xenopus Kinesin-Related Protein That Regulates Microtubule Dynamics during Mitotic Spindle Assembly , 1996, Cell.

[41]  E D Salmon,et al.  Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindle , 1994, The Journal of cell biology.

[42]  B. Schaar,et al.  Mitotic HeLa cells contain a CENP‐E‐associated minus end‐directed microtubule motor. , 1995, The EMBO journal.

[43]  J. McIntosh,et al.  Minus-end-directed motion of kinesin–coated microspheres driven by microtubule depolymerization , 1995, Nature.

[44]  G. V. Vande Woude,et al.  CENP-E is an essential kinetochore motor in maturing oocytes and is masked during mos-dependent, cell cycle arrest at metaphase II. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[45]  T. Mitchison,et al.  Mitotic spindle assembly by two different pathways in vitro , 1991, The Journal of cell biology.

[46]  Toshio Yanagida,et al.  Force measurements by micromanipulation of a single actin filament by glass needles , 1988, Nature.

[47]  M. Schliwa,et al.  Reversal in the direction of movement of a molecular motor , 1997, Nature.