Effects of Excipients on the Chemical and Physical Stability of Glucagon during Freeze-Drying and Storage in Dried Formulations
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J. Carpenter | W. Qi | S. Prestrelski | W. Fang | J. Kinzell
[1] Kenneth E. Avis,et al. Biotechnology and Biopharmaceutical Manufacturing, Processing, and Preservation , 2020 .
[2] Theodore W Randolph,et al. Inhibition of agitation-induced aggregation of an IgG-antibody by hydroxypropyl-beta-cyclodextrin. , 2010, Journal of pharmaceutical sciences.
[3] Brian M. Murphy,et al. Stability of Protein Pharmaceuticals: An Update , 2010, Pharmaceutical Research.
[4] D. Hambly,et al. The effect of sucrose hydrolysis on the stability of protein therapeutics during accelerated formulation studies. , 2009, Journal of pharmaceutical sciences.
[5] Susanne Hostrup,et al. Recent trends in stabilising peptides and proteins in pharmaceutical formulation – considerations in the choice of excipients , 2009, Expert opinion on drug delivery.
[6] Tomi Järvinen,et al. The stability and dissolution properties of solid glucagon/gamma-cyclodextrin powder. , 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[7] B. Kerwin. Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways. , 2008, Journal of pharmaceutical sciences.
[8] S. Auriola,et al. The effect of cyclodextrins on chemical and physical stability of glucagon and characterization of glucagon/gamma-CD inclusion complexes. , 2008, Journal of pharmaceutical sciences.
[9] Michael J. Pikal,et al. Protein Stability During Freezing: Separation of Stresses and Mechanisms of Protein Stabilization , 2007, Pharmaceutical development and technology.
[10] S. Yoshioka,et al. β-Relaxation of Insulin Molecule in Lyophilized Formulations Containing Trehalose or Dextran as a Determinant of Chemical Reactivity , 2006, Pharmaceutical Research.
[11] M. Sawai,et al. Studies on the mechanism of aspartic acid cleavage and glutamine deamidation in the acidic degradation of glucagon. , 2005, Journal of pharmaceutical sciences.
[12] B. Chauhan,et al. Cyclodextrins: application in different routes of drug administration. , 2005, Acta pharmaceutica.
[13] S. Onoue,et al. Mishandling of the Therapeutic Peptide Glucagon Generates Cytotoxic Amyloidogenic Fibrils , 2004, Pharmaceutical Research.
[14] N. Warne,et al. Optimizing storage stability of lyophilized recombinant human interleukin-11 with disaccharide/hydroxyethyl starch mixtures. , 2004, Journal of pharmaceutical sciences.
[15] Theodore W Randolph,et al. Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-gamma. , 2003, Journal of pharmaceutical sciences.
[16] L. Kirsch,et al. The relative rates of glutamine and asparagine deamidation in glucagon fragment 22-29 under acidic conditions. , 2002, Journal of pharmaceutical sciences.
[17] L. Kirsch,et al. The degradation pathways of glucagon in acidic solutions. , 2000, International journal of pharmaceutics.
[18] Y. Wang,et al. The formation and mechanism of multimerization in a freeze-dried peptide. , 2000, International journal of pharmaceutics.
[19] C. Schebor,et al. Stability to hydrolysis and browning of trehalose, sucrose and raffinose in low-moisture systems in relation to their use as protectants of dry biomaterials , 1999 .
[20] E. Topp,et al. Solid-state chemical stability of proteins and peptides. , 1999, Journal of pharmaceutical sciences.
[21] S. Frokjaer,et al. Effects of additives on the stability of recombinant human factor XIII during freeze-drying and storage in the dried solid. , 1998, Archives of biochemistry and biophysics.
[22] M. Manning,et al. Effect of Tween 20 on freeze-thawing- and agitation-induced aggregation of recombinant human factor XIII. , 1998, Journal of pharmaceutical sciences.
[23] Michael J. Pikal,et al. Rational Design of Stable Lyophilized Protein Formulations: Some Practical Advice , 1997, Pharmaceutical Research.
[24] B. D. Anderson,et al. Solid-state stability of human insulin. II. Effect of water on reactive intermediate partitioning in lyophiles from pH 2-5 solutions: stabilization against covalent dimer formation. , 1997, Journal of pharmaceutical sciences.
[25] B. D. Anderson,et al. Solid-State Stability of Human Insulin I. Mechanism and the Effect of Water on the Kinetics of Degradation in Lyophiles from pH 2–5 Solutions , 1996, Pharmaceutical Research.
[26] D. Granner,et al. The genes of hepatic glucose metabolism. , 1990, The Journal of biological chemistry.
[27] W. Caughey,et al. Protein secondary structures in water from second-derivative amide I infrared spectra. , 1990, Biochemistry.
[28] R. Borchardt,et al. Stability of Protein Pharmaceuticals , 1989, Pharmaceutical Research.
[29] A. D. Osborne,et al. Secondary structure and dynamics of glucagon in solution. , 1982, Biochimica et biophysica acta.
[30] K. Flanders,et al. [25-oxindolylalanine]glucagon and [27-methionine sulfoxide]glucagon: preparation, purification, and characterization. , 1982, Biochemistry.
[31] Nooijen Wj,et al. Immunogenicity and Bioactivity of Glucagon, Modified at Methionine-27 , 1979 .
[32] W. Gratzer,et al. Conformational nature of monomeric glucagon. , 1974, European journal of biochemistry.
[33] J. M. Creeth,et al. Presence ot trimers in glucagon solution. , 1972, European journal of biochemistry.
[34] W. Gratzer,et al. Relation between conformation and association state. A study of the association equilibrium of glucagon. , 1969, The Journal of biological chemistry.
[35] W. Gratzer,et al. Formation and structure of gels and fibrils from glucagon. , 1969, European journal of biochemistry.
[36] A. Puigserver,et al. Kinetics of hydrolysis of fructooligosaccharides in mineral-buffered aqueous solutions: influence of pH and temperature. , 2003, Journal of agricultural and food chemistry.
[37] Theodore W Randolph,et al. Surfactant-protein interactions. , 2002, Pharmaceutical biotechnology.
[38] W. Caughey,et al. Infrared methods for study of hemoglobin reactions and structures. , 1994, Methods in enzymology.
[39] H. Kempen,et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. , 1979, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.