Inducible nitric oxide synthase deficiency promotes murine-β-coronavirus induced demyelination

[1]  S. Elledge,et al.  Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis , 2022, Science.

[2]  B. Saha,et al.  CD40L protects against mouse hepatitis virus-induced neuroinflammatory demyelination , 2021, PLoS pathogens.

[3]  P. Rayman,et al.  Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection , 2020, PLoS pathogens.

[4]  I. Amit,et al.  Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer , 2020, Cell.

[5]  K. Shindler,et al.  CD4 Deficiency Causes Poliomyelitis and Axonal Blebbing in Murine Coronavirus-Induced Neuroinflammation , 2020, Journal of Virology.

[6]  G. Lal,et al.  The iNOS Activity During an Immune Response Controls the CNS Pathology in Experimental Autoimmune Encephalomyelitis , 2019, Front. Immunol..

[7]  D. Pal,et al.  A proline insertion-deletion in the spike glycoprotein fusion peptide of mouse hepatitis virus strongly alters neuropathology , 2019, The Journal of Biological Chemistry.

[8]  M. Simons,et al.  Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model , 2018, Nature Neuroscience.

[9]  S. Perlman,et al.  Microglia are required for protection against lethal coronavirus encephalitis in mice , 2018, The Journal of clinical investigation.

[10]  F. Feng,et al.  Inhibiting Interleukin 17 Can Ameliorate the Demyelination Caused by A. cantonensis via iNOS Inhibition , 2017, Mediators of inflammation.

[11]  A. D. de Vos,et al.  Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages. , 2016, Cell reports.

[12]  C. Bogdan Nitric oxide synthase in innate and adaptive immunity: an update. , 2015, Trends in immunology.

[13]  R. Cohrs,et al.  Mouse Hepatitis Virus Infection Upregulates Genes Involved in Innate Immune Responses , 2014, PloS one.

[14]  I. Müller,et al.  Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages , 2014, Front. Immunol..

[15]  A. Maghazachi,et al.  Multiple sclerosis and the role of immune cells. , 2014, World journal of experimental medicine.

[16]  J. D. Sarma Microglia-mediated neuroinflammation is an amplifier of virus-induced neuropathology , 2014, Journal of NeuroVirology.

[17]  C. Rapôso,et al.  Sildenafil (Viagra) Protective Effects on Neuroinflammation: The Role of iNOS/NO System in an Inflammatory Demyelination Model , 2013, Mediators of inflammation.

[18]  S. Weiss,et al.  Enhanced green fluorescent protein expression may be used to monitor murine coronavirus spread in vitro and in the mouse central nervous system , 2002, Journal of NeuroVirology.

[19]  T. Lane,et al.  Lack of nitric oxide synthase type 2 (NOS2) results in reduced neuronal apoptosis and mortality following mouse hepatitis virus infection of the central nervous system , 2002, Journal of NeuroVirology.

[20]  K. Shindler,et al.  Mechanisms of Primary Axonal Damage in a Viral Model of Multiple Sclerosis , 2009, The Journal of Neuroscience.

[21]  H. Neumann,et al.  Debris clearance by microglia: an essential link between degeneration and regeneration , 2008, Brain : a journal of neurology.

[22]  K. Shindler,et al.  Experimental Optic Neuritis Induced by a Demyelinating Strain of Mouse Hepatitis Virus , 2008, Journal of Virology.

[23]  Z. Goodman Grading and staging systems for inflammation and fibrosis in chronic liver diseases. , 2007, Journal of hepatology.

[24]  D. Quiceno,et al.  L-arginine availability regulates T-lymphocyte cell-cycle progression. , 2007, Blood.

[25]  H. Neumann,et al.  Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2 , 2005, The Journal of experimental medicine.

[26]  J. Rose,et al.  Inducible nitric oxide synthase in chronic active multiple sclerosis plaques: distribution, cellular expression and association with myelin damage , 2004, Journal of Neuroimmunology.

[27]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[28]  J. Ting,et al.  The Protective Role of Nitric Oxide in a Neurotoxicant- Induced Demyelinating Model1 , 2002, The Journal of Immunology.

[29]  S. Ghosh,et al.  Ligation of CD40 Stimulates the Induction of Nitric-oxide Synthase in Microglial Cells* , 2001, The Journal of Biological Chemistry.

[30]  Christian Bogdan,et al.  Nitric oxide and the immune response , 2001, Nature Immunology.

[31]  Gregory F. Wu,et al.  Coronavirus-Induced Demyelination Occurs in the Absence of Inducible Nitric Oxide Synthase , 2000, Journal of Virology.

[32]  Gregory F. Wu,et al.  Macrophage Infiltration, but Not Apoptosis, Is Correlated with Immune-Mediated Demyelination following Murine Infection with a Neurotropic Coronavirus , 1999, Journal of Virology.

[33]  L. Ignarro,et al.  Cutting Edge: Antisense Knockdown of Inducible Nitric Oxide Synthase Inhibits Induction of Experimental Autoimmune Encephalomyelitis in SJL/J Mice , 1998, The Journal of Immunology.

[34]  J. Weidner,et al.  This information is current as Gene NOS 2 Exacerbated in Mice Lacking the Experimental Autoimmune Encephalomyelitis Is , 1998 .

[35]  P. Stahl,et al.  The mannose receptor is a pattern recognition receptor involved in host defense. , 1998, Current opinion in immunology.

[36]  L. Ignarro,et al.  Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice. , 1998, Journal of immunology.

[37]  R. Sobel,et al.  Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis. , 1997, Journal of immunology.

[38]  J. Merrill,et al.  The role of nitric oxide in multiple sclerosis , 1997, Journal of Molecular Medicine.

[39]  M. Mcdaniel,et al.  Experimental allergic encephalomyelitis in the rat is inhibited by aminoguanidine, an inhibitor of nitric oxide synthase , 1996, Journal of Neuroimmunology.

[40]  O. Smithies,et al.  Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[41]  H. Hartung,et al.  Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis , 1995, Journal of Neuroimmunology.

[42]  Carl Nathan,et al.  Nitric oxide synthases: Roles, tolls, and controls , 1994, Cell.

[43]  A. Cross,et al.  Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice. , 1994, The Journal of clinical investigation.

[44]  D. McFarlin,et al.  Immunological aspects of demyelinating diseases. , 1992, Annual review of immunology.

[45]  D. Gilden,et al.  Persistence of mouse hepatitis virus A59 RNA in a slow virus demyelinating infection in mice as detected by in situ hybridization , 1984, Journal of virology.

[46]  L. Rorke,et al.  Experimental demyelination produced by the A59 strain of mouse hepatitis virus , 1984, Neurology.