Sinogram restoration for low-dose X-ray computed tomography using regularized Perona–Malik equation with intuitionistic fuzzy entropy

Edges and flat areas in the sinogram of low-dose X-ray computed tomography are difficult to distinguish. This lack of distinction leads to excessive smoothing in the sinogram restoration. To address this problem, we propose a sinogram restoration algorithm using the regularized Perona–Malik (P–M) equation with intuitionistic fuzzy entropy. Firstly, considering the sinogram fuzziness, a novel edge indicator function is constructed using both the gradient magnitude and intuitionistic fuzzy entropy. Secondly, using the constructed edge indicator function as the diffusion coefficient, a novel regularized P–M equation smoothing model is presented. The proposed model overcomes the shortage of traditional P–M equations, which are ill-conditioned. Moreover, it performs diffusion with different directions and intensities in different regions of the sinogram. The optimal solution of the proposed algorithm is obtained by using the additional operator splitting method. Finally, the reconstructed image is achieved by filtered back projection from the smoothed sinogram. Experimental results show that the presented method can retain important edges while smoothing noise and perform better than others.

[1]  Quan Zhang,et al.  Noise Reduction for Low-dose CT Sinogram Based on Fuzzy Entropy: Noise Reduction for Low-dose CT Sinogram Based on Fuzzy Entropy , 2014 .

[2]  Ioannis K. Vlachos,et al.  Inner Product Based Entropy in the Intuitionistic Fuzzy Setting , 2006, Int. J. Uncertain. Fuzziness Knowl. Based Syst..

[3]  W. Kalender,et al.  Generalized multi-dimensional adaptive filtering for conventional and spiral single-slice, multi-slice, and cone-beam CT. , 2001, Medical physics.

[4]  Zhengrong Liang,et al.  Dose reduction for kilovotage cone-beam computed tomography in radiation therapy. , 2008, Physics in medicine and biology.

[5]  Yuanke Zhang,et al.  Statistical Sinogram Smoothing for Low-Dose CT With Segmentation-Based Adaptive Filtering , 2010, IEEE Transactions on Nuclear Science.

[6]  Luo Ouyang,et al.  Noise correlation in CBCT projection data and its application for noise reduction in low-dose CBCT. , 2014, Medical physics.

[7]  Yi Liu,et al.  The statistical sinogram smoothing via adaptive-weighted total variation regularization for low-dose X-ray CT , 2014 .

[8]  Euclid Seeram,et al.  Computed Tomography: Physical Principles, Clinical Applications, and Quality Control , 1994 .

[9]  Jing Wang,et al.  Multiscale Penalized Weighted Least-Squares Sinogram Restoration for Low-Dose X-Ray Computed Tomography , 2008, IEEE Transactions on Biomedical Engineering.

[10]  Janusz Kacprzyk,et al.  Entropy for intuitionistic fuzzy sets , 2001, Fuzzy Sets Syst..

[11]  Joachim Hornegger,et al.  Ray Contribution Masks for Structure Adaptive Sinogram Filtering , 2012, IEEE Transactions on Medical Imaging.

[12]  P. Lions,et al.  Image selective smoothing and edge detection by nonlinear diffusion. II , 1992 .

[13]  Daniel Kolditz,et al.  Iterative reconstruction methods in X-ray CT. , 2012, Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics.

[14]  Jitendra Malik,et al.  Scale-Space and Edge Detection Using Anisotropic Diffusion , 1990, IEEE Trans. Pattern Anal. Mach. Intell..

[15]  Huazhong Shu,et al.  Artifact Suppressed Dictionary Learning for Low-Dose CT Image Processing , 2014, IEEE Transactions on Medical Imaging.

[16]  K. P. Kim,et al.  Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study , 2012, The Lancet.

[17]  Krassimir T. Atanassov,et al.  Intuitionistic fuzzy sets , 1986 .

[18]  G. Zeng Noise-weighted spatial domain FBP algorithm. , 2014, Medical physics.

[19]  Jing Wang Noise reduction for low-dose x-ray computed tomography , 2006 .

[20]  Max A. Viergever,et al.  Efficient and reliable schemes for nonlinear diffusion filtering , 1998, IEEE Trans. Image Process..

[21]  Quan Zhang,et al.  Noise reduction for low-dose X-ray CT based on fuzzy logical in stationary wavelet domain , 2013 .

[22]  Limin Luo,et al.  Bayesian sinogram smoothing with an anisotropic diffusion weighted prior for low-dose X-ray computed tomography , 2013 .

[23]  Quan Zhang,et al.  Low-dose CT statistical iterative reconstruction via modified MRF regularization , 2016, Comput. Methods Programs Biomed..

[24]  J. Hsieh Adaptive streak artifact reduction in computed tomography resulting from excessive x-ray photon noise. , 1998, Medical physics.

[25]  Amir Nakib,et al.  Medical image denoising via optimal implementation of non-local means on hybrid parallel architecture , 2016, Comput. Methods Programs Biomed..