Toxicity of cationic lipids and cationic polymers in gene delivery.
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Shubiao Zhang | Hongtao Lv | B. Wang | S. Cui | Jie Yan | Shubiao Zhang | Hongtao Lv | Bing Wang | Shaohui Cui | Jie Yan
[1] A. Balaban,et al. Pyridinium‐Based Cationic Lipids as Gene‐Transfer Agents , 2003 .
[2] F. Devínsky,et al. Amphiphilic detergents inhibit production of IgG and IgM by human peripheral blood mononuclear cells. , 1993, Immunology Letters.
[3] Dexi Liu,et al. Synthesis of bifunctional cationic compound for gene delivery , 2001 .
[4] Lisbeth Illum,et al. Chitosan as a Novel Nasal Delivery System for Peptide Drugs , 1994, Pharmaceutical Research.
[5] A. Chaudhuri,et al. Common co‐lipids, in synergy, impart high gene transfer properties to transfection‐incompetent cationic lipids , 2005, FEBS letters.
[6] L. Schmitt,et al. Use of a quaternary ammonium detergent in liposome mediated DNA transfection of mouse L-cells. , 1989, Biochimica et biophysica acta.
[7] T. Yotsuyanagi,et al. Effect of oligopeptides on gene expression: comparison of DNA/peptide and DNA/peptide/liposome complexes. , 2004, International journal of pharmaceutics.
[8] C. Y. Chow,et al. A novel series of amphiphilic imidazolinium compounds for in vitro and in vivo gene delivery. , 1995, Biochemistry.
[9] A. Maheshwari,et al. Biodegradable polymer-based interleukin-12 gene delivery: role of induced cytokines, tumor infiltrating cells and nitric oxide in anti-tumor activity , 2002, Gene Therapy.
[10] J. Ruysschaert,et al. The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids , 1997, FEBS letters.
[11] K. Ulbrich,et al. Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA. , 1999, Bioconjugate chemistry.
[12] Duane D. Miller,et al. Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery. , 2002, Biomacromolecules.
[13] D. Scherman,et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[14] M. Nantz,et al. A novel tetraester construct that reduces cationic lipid-associated cytotoxicity. Implications for the onset of cytotoxicity. , 1998, Biochemistry.
[15] J. Northrop,et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[16] R. Mahato. Water insoluble and soluble lipids for gene delivery. , 2005, Advanced drug delivery reviews.
[17] H. Gao,et al. Synthesis of a novel series of cationic lipids that can act as efficient gene delivery vehicles through systematic heterocyclic substitution of cholesterol derivatives , 2001, Gene Therapy.
[18] D. Lasič. LIPOSOMES in GENE DELIVERY , 1997 .
[19] S. Hart,et al. A nonviral vector system for efficient gene transfer to corneal endothelial cells via membrane integrins. , 1997, Transplantation.
[20] P. Reynier,et al. A hydroxyethylated cholesterol-based cationic lipid for DNA delivery: effect of conditioning. , 2004, International journal of pharmaceutics.
[21] E. Canning,et al. A triploblast origin for Myxozoa? , 1998, Nature.
[22] A. El-Aneed,et al. An overview of current delivery systems in cancer gene therapy. , 2004, Journal of controlled release : official journal of the Controlled Release Society.
[23] W. Hennink,et al. A comparative study of different cationic transfection agents for in vivo gene delivery after intravenous administration , 2004 .
[24] C. Dass. Vehicles for oligonucleotide delivery to tumours , 2002, The Journal of pharmacy and pharmacology.
[25] N. Phillips,et al. Toxicity and immunomodulatory activity of liposomal vectors formulated with cationic lipids toward immune effector cells. , 1997, Biochimica et biophysica acta.
[26] P. Cullis,et al. On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids , 2001, Gene Therapy.
[27] C. Pouton,et al. Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids. , 1998, Journal of controlled release : official journal of the Controlled Release Society.
[28] Y. Barenholz,et al. Novel dextran–spermine conjugates as transfecting agents: comparing water-soluble and micellar polymers , 2005, Gene Therapy.
[29] D. Hoekstra,et al. Novel pyridinium surfactants for efficient, nontoxic in vitro gene delivery. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[30] A. Balaban,et al. Pyridinium cationic lipids in gene delivery: an in vitro and in vivo comparison of transfection efficiency versus a tetraalkylammonium congener. , 2005, Archives of biochemistry and biophysics.
[31] Takuro Niidome,et al. In vitro gene transfection using dendritic poly(L-lysine). , 2002, Bioconjugate chemistry.
[32] D. Fischer,et al. A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity , 1999, Pharmaceutical Research.
[33] T. Schiestel,et al. A nonviral DNA delivery system based on surface modified silica-nanoparticles can efficiently transfect cells in vitro. , 2000, Bioconjugate chemistry.
[34] Z. Bebők,et al. Gene delivery systems--gene therapy vectors for cystic fibrosis. , 2004, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.
[35] M. Hashida,et al. Interaction between DNA–cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid , 2001, Gene Therapy.
[36] M. Linial,et al. Quaternary ammonium polysaccharides for gene delivery. , 2005, Bioconjugate chemistry.
[37] Clive J Roberts,et al. Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. , 2002, Bioconjugate chemistry.
[38] C. Dass. Biochemical and biophysical characteristics of lipoplexes pertinent to solid tumour gene therapy. , 2002, International journal of pharmaceutics.
[39] H. Junginger,et al. Chitosan and its derivatives as intestinal absorption enhancers. , 2001, Advanced drug delivery reviews.
[40] J H Senior,et al. Interaction of positively-charged liposomes with blood: implications for their application in vivo. , 1991, Biochimica et biophysica acta.
[41] R. Epand,et al. Effect of cationic cholesterol derivatives on gene transfer and protein kinase C activity. , 1992, Biochimica et biophysica acta.
[42] A. Göpferich,et al. Polyethylenimine-based non-viral gene delivery systems. , 2005, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[43] M. D. Brown,et al. Preliminary characterization of novel amino acid based polymeric vesicles as gene and drug delivery agents. , 2000, Bioconjugate chemistry.
[44] C H Wu,et al. Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. , 1987, The Journal of biological chemistry.
[45] A. Rolland. Gene medicines: the end of the beginning? , 2005, Advanced drug delivery reviews.
[46] C. Férec,et al. Cation substitution in cationic phosphonolipids: a new concept to improve transfection activity and decrease cellular toxicity. , 2000, Journal of medicinal chemistry.
[47] A. Urtti,et al. Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies. , 1999, Biochimica et biophysica acta.
[48] Takuro Niidome,et al. Characters of dendritic poly(L-lysine) analogues with the terminal lysines replaced with arginines and histidines as gene carriers in vitro. , 2004, Biomaterials.
[49] Dongliang Liu,et al. Synthesis and characterization of a series of carbamate-linked cationic lipids for gene delivery , 2005, Lipids.
[50] D. Thompson,et al. Synthesis of acid-labile diplasmenyl lipids for drug and gene delivery applications. , 1999, Chemistry and physics of lipids.
[51] A. Mikos,et al. Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle. , 1999, Journal of biomedical materials research.
[52] R. Kumar,et al. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. , 1994, The Journal of biological chemistry.
[53] Martin L Read,et al. Systemic circulation of poly(L-lysine)/DNA vectors is influenced by polycation molecular weight and type of DNA: differential circulation in mice and rats and the implications for human gene therapy. , 2001, Blood.
[54] W. Hennink,et al. Endosomal Escape of Polymeric Gene Delivery Complexes Is Not Always Enhanced by Polymers Buffering at Low pH , 2004 .
[55] Michael J. Derelanko,et al. Handbook of Toxicology , 2001 .
[56] S. W. Kim,et al. Water-soluble lipopolymer for gene delivery. , 2001, Bioconjugate chemistry.
[57] J. Hughes,et al. Synthesis of a single-tailed cationic lipid and investigation of its transfection. , 1999, Journal of controlled release : official journal of the Controlled Release Society.
[58] K. Ulbrich,et al. Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate‐mediated targeting in vitro and prolonged plasma circulation in vivo , 2002, The journal of gene medicine.
[59] Shubiao Zhang,et al. Cationic compounds used in lipoplexes and polyplexes for gene delivery. , 2004, Journal of controlled release : official journal of the Controlled Release Society.
[60] A. Roosjen,et al. Synthesis and characteristics of biodegradable pyridinium amphiphiles used for in vitro DNA delivery , 2002 .
[61] E. Schacht,et al. Structure-activity relationships of poly(L-lysines): effects of pegylation and molecular shape on physicochemical and biological properties in gene delivery. , 2002, Journal of controlled release : official journal of the Controlled Release Society.
[62] D. Thompson,et al. Formation of Plasmid-Based Transfection Complexes with an Acid-Labile Cationic Lipid: Characterization of in Vitro and in Vivo Gene Transfer , 2002, Pharmaceutical Research.
[63] Sung Wan Kim,et al. Water-Soluble and Low Molecular Weight Chitosan-Based Plasmid DNA Delivery , 2001, Pharmaceutical Research.
[64] T. Elliott,et al. Solid-phase synthesis of 89 polyamine-based cationic lipids for DNA delivery to mammalian cells. , 2004, Chemistry.
[65] J. H. Li,et al. Toxicity of cationic lipid-ribozyme complexes in human prostate tumor cells can mimic ribozyme activity. , 1996, Biochemical and molecular medicine.
[66] C. van Nostrum,et al. Polymer Side-Chain Degradation as a Tool to Control the Destabilization of Polyplexes , 2004, Pharmaceutical Research.
[67] Sanchita Bhattacharya,et al. Characterization of cationic lipid-protamine–DNA (LPD) complexes for intravenous gene delivery , 1998, Gene Therapy.
[68] Manouchehr Mirshahi,et al. Efficacy of dendrimer‐mediated angiostatin and TIMP‐2 gene delivery on inhibition of tumor growth and angiogenesis: In vitro and in vivo studies , 2003, International journal of cancer.
[69] A. Mikos,et al. Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency , 1999, Gene Therapy.
[70] R. Epand,et al. Inhibition of protein kinase C by cationic amphiphiles. , 1992, Biochemistry.
[71] A. Mikos,et al. Poly(ethylenimine) and its role in gene delivery. , 1999, Journal of controlled release : official journal of the Controlled Release Society.
[72] Jianjun Hu,et al. Synthesis of carbamate-linked lipids for gene delivery. , 2005, Bioorganic & medicinal chemistry letters.
[73] S. W. Kim,et al. Development of biomaterials for gene therapy. , 2000, Molecular therapy : the journal of the American Society of Gene Therapy.
[74] K. Yao,et al. Chitosan and its derivatives--a promising non-viral vector for gene transfection. , 2002 .
[75] C. Springer,et al. Synthesis of novel cationic lipids: effect of structural modification on the efficiency of gene transfer. , 2002, Journal of medicinal chemistry.
[76] C. van Nostrum,et al. Cationic polymethacrylates with covalently linked membrane destabilizing peptides as gene delivery vectors. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[77] D. Friend,et al. Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. , 1996, Biochimica et biophysica acta.
[78] Lonnie D Shea,et al. Controlled release systems for DNA delivery. , 2004, Molecular therapy : the journal of the American Society of Gene Therapy.
[79] Sung Wan Kim,et al. Polyethylenimine with acid-labile linkages as a biodegradable gene carrier. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[80] L. Smith,et al. Peptide-based gene delivery. , 1999, Current opinion in molecular therapeutics.
[81] Kari Syrjänen,et al. Comparison of Cell Proliferation and Toxicity Assays Using Two Cationic Liposomes , 1994, Pharmaceutical Research.
[82] Lisbeth Illum,et al. Effect of Chitosan on the Permeability of Monolayers of Intestinal Epithelial Cells (Caco-2) , 1994, Pharmaceutical Research.
[83] S. Funari,et al. Biophysical and biochemical properties of a binary lipid mixture for DNA transfection. , 2005, Colloids and surfaces. B, Biointerfaces.
[84] D. Fischer,et al. Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[85] M. Hashida,et al. Targeted delivery of plasmid DNA to hepatocytes in vivo: optimization of the pharmacokinetics of plasmid DNA/galactosylated poly(L-lysine) complexes by controlling their physicochemical properties. , 1998, The Journal of pharmacology and experimental therapeutics.
[86] Qing Ge,et al. Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[87] K. Heider,et al. Polycation‐based DNA complexes for tumor‐targeted gene delivery in vivo , 1999, The journal of gene medicine.
[88] F. Szoka,et al. Physicochemical characterization and purification of cationic lipoplexes. , 1999, Biophysical journal.
[89] S. Kawakami,et al. Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes. , 1998, Biochemical and biophysical research communications.
[90] H. Strey,et al. Improved DNA: liposome complexes for increased systemic delivery and gene expression , 1997, Nature Biotechnology.
[91] J. Cusack,et al. Introduction to cancer gene therapy. , 2002, Surgical oncology clinics of North America.
[92] R. Leventis,et al. Interactions of mammalian cells with lipid dispersions containing novel metabolizable cationic amphiphiles. , 1990, Biochimica et biophysica acta.
[93] P. Artursson,et al. Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo , 2003, The journal of gene medicine.
[94] J. Kroeze,et al. Synthesis of Pyridinium Amphiphiles Used for Transfection and Some Characteristics of Amphiphile/DNA Complex Formation , 2000 .
[95] Y. Barenholz,et al. Dextran-spermine-based polyplexes--evaluation of transgene expression and of local and systemic toxicity in mice. , 2006, Biomaterials.
[96] J. S. Park,et al. New cationic liposomes for gene transfer into mammalian cells with high efficiency and low toxicity. , 2001, Bioconjugate chemistry.
[97] F. Devínsky,et al. Immunomodulatory activity of some amphiphilic compounds. , 1990, Die Pharmazie.
[98] P. Hornsby,et al. Transfection by Polyethyleneimine-Coated Microspheres , 2001, Journal of drug targeting.
[99] J. Ruysschaert,et al. Formation and intracellular trafficking of lipoplexes and polyplexes. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.
[100] D. Fischer,et al. Poly(ethylenimine-co-L-lactamide-co-succinamide): a biodegradable polyethylenimine derivative with an advantageous pH-dependent hydrolytic degradation for gene delivery. , 2002, Bioconjugate chemistry.
[101] R. Ghirlando,et al. Mode of formation and structural features of DNA-cationic liposome complexes used for transfection. , 1993, Biochemistry.
[102] F. Alexis,et al. Low molecular weight polyethylenimines linked by β‐cyclodextrin for gene transfer into the nervous system , 2006, The journal of gene medicine.
[103] A. Mikos,et al. Poly(ethylenimine)-mediated gene delivery affects endothelial cell function and viability. , 2001, Biomaterials.
[104] J. Mcgregor,et al. Soluble biodegradable polymer-based cytokine gene delivery for cancer treatment. , 2000, Molecular therapy : the journal of the American Society of Gene Therapy.
[105] N. Weiner,et al. Application of membrane-based dendrimer/DNA complexes for solid phase transfection in vitro and in vivo. , 2000, Biomaterials.
[106] P. Searle,et al. Vectors based on reducible polycations facilitate intracellular release of nucleic acids , 2003, The journal of gene medicine.