EZH2-DNMT1-mediated epigenetic silencing of miR-142-3p promotes metastasis through targeting ZEB2 in nasopharyngeal carcinoma

[1]  Eld,et al.  TRPA1–FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p , 2017, Nature Communications.

[2]  Eui Tae Kim,et al.  Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. , 2017, The Journal of clinical investigation.

[3]  Jianji Pan,et al.  Gemcitabine plus cisplatin versus fluorouracil plus cisplatin in recurrent or metastatic nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase 3 trial , 2016, The Lancet.

[4]  S. Capitani,et al.  A network including PU.1, Vav1 and miR-142-3p sustains ATRA-induced differentiation of acute promyelocytic leukemia cells - a short report , 2016, Cellular Oncology.

[5]  Xinran Tang,et al.  Overexpression of Mitochondria Mediator Gene TRIAP1 by miR-320b Loss Is Associated with Progression in Nasopharyngeal Carcinoma , 2016, PLoS genetics.

[6]  G. Getz,et al.  The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis , 2016, Nature Genetics.

[7]  A. Shilatifard,et al.  Epigenetic balance of gene expression by Polycomb and COMPASS families , 2016, Science.

[8]  Andrew J. Ewald,et al.  A collective route to metastasis: Seeding by tumor cell clusters , 2016, Science.

[9]  Edwin P Hui,et al.  Nasopharyngeal carcinoma , 2016, The Lancet.

[10]  A. Jemal,et al.  Cancer statistics in China, 2015 , 2016, CA: a cancer journal for clinicians.

[11]  Ying Sun,et al.  Genome-Wide Identification of a Methylation Gene Panel as a Prognostic Biomarker in Nasopharyngeal Carcinoma , 2015, Molecular Cancer Therapeutics.

[12]  Xiaoming Qi,et al.  MiR-142-3p Suppresses SOCS6 Expression and Promotes Cell Proliferation in Nasopharyngeal Carcinoma , 2015, Cellular Physiology and Biochemistry.

[13]  T. Chan,et al.  Mycophenolic acid upregulates miR-142-3P/5P and miR-146a in lupus CD4+T cells , 2015, Lupus.

[14]  P. Boutros,et al.  Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma , 2015, Oncotarget.

[15]  Xinran Tang,et al.  MiR-34c suppresses tumor growth and metastasis in nasopharyngeal carcinoma by targeting MET , 2015, Cell Death and Disease.

[16]  Y Sun,et al.  A Bayesian network meta-analysis comparing concurrent chemoradiotherapy followed by adjuvant chemotherapy, concurrent chemoradiotherapy alone and radiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma. , 2015, Annals of oncology : official journal of the European Society for Medical Oncology.

[17]  D. Peeper,et al.  Phenotype switching: tumor cell plasticity as a resistance mechanism and target for therapy. , 2014, Cancer research.

[18]  Luca Magnani,et al.  Poised epigenetic states and acquired drug resistance in cancer , 2014, Nature Reviews Cancer.

[19]  G. Fuller,et al.  Effect of miR-142-3p on the M2 macrophage and therapeutic efficacy against murine glioblastoma. , 2014, Journal of the National Cancer Institute.

[20]  Y. Nie,et al.  Forkhead box Q1 promotes hepatocellular carcinoma metastasis by transactivating ZEB2 and VersicanV1 expression , 2014, Hepatology.

[21]  M. Fabbri,et al.  MicroRNAs and other non-coding RNAs as targets for anticancer drug development , 2013, Nature Reviews Drug Discovery.

[22]  Jiao Gao,et al.  miR-142-3p regulates the formation and differentiation of hematopoietic stem cells in vertebrates , 2013, Cell Research.

[23]  Ying Sun,et al.  MiR-451 inhibits cell growth and invasion by targeting MIF and is associated with survival in nasopharyngeal carcinoma , 2013, Molecular Cancer.

[24]  P. Lipsky,et al.  miR-142-3p Is Involved in CD25+ CD4 T Cell Proliferation by Targeting the Expression of Glycoprotein A Repetitions Predominant , 2013, The Journal of Immunology.

[25]  Subbaya Subramanian,et al.  Triptolide Induces the Expression of miR-142-3p: A Negative Regulator of Heat Shock Protein 70 and Pancreatic Cancer Cell Proliferation , 2013, Molecular Cancer Therapeutics.

[26]  Hiroya Tamaki,et al.  PU.1-Dependent Transcriptional Regulation of miR-142 Contributes to Its Hematopoietic Cell–Specific Expression and Modulation of IL-6 , 2013, The Journal of Immunology.

[27]  C. Cordon-Cardo,et al.  A common MicroRNA signature consisting of miR-133a, miR-139-3p, and miR-142-3p clusters bladder carcinoma in situ with normal umbrella cells. , 2013, The American journal of pathology.

[28]  Ying Sun,et al.  Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. , 2012, The Lancet. Oncology.

[29]  Li-Rong Chen,et al.  miR-29a and miR-142-3p downregulation and diagnostic implication in human acute myeloid leukemia , 2012, Molecular Biology Reports.

[30]  E. Li,et al.  MiR‐142‐3p as a potential prognostic biomarker for esophageal squamous cell carcinoma , 2012, Journal of surgical oncology.

[31]  Ying Sun,et al.  Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised controlled trial. , 2012, The Lancet. Oncology.

[32]  Min Liu,et al.  MicroRNA‐142‐3p, a new regulator of RAC1, suppresses the migration and invasion of hepatocellular carcinoma cells , 2011, FEBS letters.

[33]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[34]  Zhuoshun Yang,et al.  Selective depletion of CD4+CD25+Foxp3+ regulatory T cells by low-dose cyclophosphamide is explained by reduced intracellular ATP levels. , 2010, Cancer research.

[35]  Robert A. Weinberg,et al.  Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. , 2008, Developmental cell.

[36]  A. G. de Herreros,et al.  A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. , 2008, Genes & development.

[37]  Ying Liang,et al.  Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signaling. , 2006, Cancer research.

[38]  C. Croce,et al.  MicroRNA signatures in human cancers , 2006, Nature Reviews Cancer.

[39]  F. Slack,et al.  Oncomirs — microRNAs with a role in cancer , 2006, Nature Reviews Cancer.

[40]  M. Fraga,et al.  The Polycomb group protein EZH2 directly controls DNA methylation , 2006, Nature.

[41]  J. Sham,et al.  Nasopharyngeal carcinoma , 2005, The Lancet.

[42]  V. Ambros.  The functions of animal microRNAs , 2004, Nature.

[43]  Lin He,et al.  MicroRNAs: small RNAs with a big role in gene regulation , 2004, Nature Reviews Genetics.

[44]  Lin He,et al.  MicroRNAs: small RNAs with a big role in gene regulation , 2004, Nature Reviews Genetics.

[45]  V. Ambros,et al.  A short history of a short RNA , 2004, Cell.

[46]  D. Bartel.  MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[47]  D. Bartel,et al.  MicroRNAs Modulate Hematopoietic Lineage Differentiation , 2004, Science.

[48]  M. Loda,et al.  The EZH2 polycomb transcriptional repressor--a marker or mover of metastatic prostate cancer? , 2002, Cancer cell.

[49]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[50]  D. Haber,et al.  DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development , 1999, Cell.

[51]  M. Zweig,et al.  Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. , 1993, Clinical chemistry.

[52]  Pelayo Vilar,et al.  Nasopharyngeal Carcinoma , 1966 .

[53]  Bi-Jun Huang,et al.  IL-8 suppresses E-cadherin expression in nasopharyngeal carcinoma cells by enhancing E-cadherin promoter DNA methylation. , 2016, International journal of oncology.

[54]  Jean Paul Thiery,et al.  EMT: 2016 , 2016, Cell.

[55]  Stephen T. C. Wong,et al.  EMT is not required for lung metastasis but contributes to chemoresistance , 2016 .

[56]  S. Lange,et al.  Expression and prognostic significance of hsa-miR-142-3p in acute leukemias. , 2013, Neoplasma.

[57]  A. Bird.  DNA methylation patterns and epigenetic memory. , 2002, Genes & development.