Pattern of Lung Cancer in Turkey, 1994–1998

Background: Lung cancer is the most common neoplasm in Turkey, but there is not enough data on the characteristics of this mortal illness in our country. Objectives and Methods: The Turkish Thoracic Society, Lung and Pleural Malignancies Study Group (TTS-LPMSG) conducted a national retrospective hospital-based study to determine the pattern of lung cancer in Turkey. Results: A total of 11,849 lung cancer patients were studied between 1994 and 1998, 90.4% were male and 9.6% were female. The majority of patients were smokers (77.9%) or ex-smokers (10.8%). The mean age at the time of diagnosis was 58.4 years (20–84) and 56.7% of the patients were aged between 46 and 65 years. The most common histological types were squamous cell (45.4%), small cell (SCLC; 20.5%) and adenocarcinoma (20.2%). The majority of patients with non-small-cell lung cancer were diagnosed with metastatic disease (40.4%). Of the patients with SCLC patients, 37.9% had limited stage disease and 62.7% extensive stage disease at diagnosis. Conclusion: The results of the largest data so far collected in Turkey show that the vast majority of patients with lung cancer are male, squamous cell is the most common histological type, and only a small proportion of patients are diagnosed at an early stage.

[1]  Y. Koh,et al.  Characteristics of lung cancer in Korea, 1997. , 2000, Lung cancer.

[2]  J. Olsen,et al.  Incidence of lung cancer in Denmark: historical and actual status. , 1999, Lung cancer.

[3]  R. Marks,et al.  Current guidelines for the management of small cell lung cancer. , 1999, Mayo Clinic proceedings.

[4]  G. Gürsel,et al.  Hospital based survey of lung cancer in Turkey, a developing country, where smoking is highly prevalent. , 1998, Lung cancer.

[5]  M. Rossignol,et al.  International differences in epidemiology of lung adenocarcinoma. , 1997, Lung cancer.

[6]  W. Travis,et al.  United States lung carcinoma incidence trends: Declining for most histologic types among males, increasing among females , 1996, Cancer.

[7]  D Hoffmann,et al.  Smoking and lung cancer: scientific challenges and opportunities. , 1994, Cancer research.

[8]  J. Samet The epidemiology of lung cancer. , 1993, Chest.

[9]  O. Matsubara,et al.  Increasing incidence and changing histopathology of primary lung cancer in Japan. A review of 282 autopsied cases , 1988, Cancer.

[10]  Y. Shimosato,et al.  Histological Typing of Lung Tumours 1 , 1981 .

[11]  B. Yorulmaz,et al.  Pleural calcification, pleural mesotheliomas, and bronchial cancers caused by tremolite dust. , 1980, Thorax.

[12]  I. Todd,et al.  Bronchial Carcinoma , 1930, Edinburgh Medical Journal.

[13]  S. Eser,et al.  Incidence in Izmir in 1993-1994: first results from Izmir Cancer Registry. , 2001, European journal of cancer.

[14]  R. Hubbard,et al.  Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study. , 2000, American journal of respiratory and critical care medicine.

[15]  A. Jemal,et al.  Global cancer statistics , 2011, CA: a cancer journal for clinicians.

[16]  Taylor Murray,et al.  Cancer statistics, 1998 , 1998, CA: a cancer journal for clinicians.

[17]  H. Hansen,et al.  Lung cancer. , 1990, Cancer chemotherapy and biological response modifiers.

[18]  D. Ferluga,et al.  [Pulmonary scar cancer and tumourlet (author's transl)]. , 1979, Praxis und Klinik der Pneumologie.

[19]  AJ McMichael,et al.  Have increases in solar ultraviolet exposure contributed to the rise in incidence of non-Hodgkin's lymphoma? , 1996, British Journal of Cancer.