3,5,6-Trichloro-2-pyridinol confirms ototoxicity in mouse cochlear organotypic cultures and induces cytotoxicity in HEI-OC1 cells.
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F. Lian | Yu Hong | Shuangshuang Mao | Haiyan Wang | Lei Yang | Rong Chen | Fei Gui | Wenqi Xu | Mingshan Zou | Mao Huang
[1] Yingzi He,et al. 20(S)-Ginsenoside Rh1 inhibits cisplatin-induced hearing loss by inhibiting the MAPK signaling pathway and suppressing apoptosis in vitro. , 2023, Biochimica et biophysica acta. Molecular cell research.
[2] Jianyun Zhang,et al. Exploring the effects and mechanisms of organophosphorus pesticide exposure and hearing loss , 2022, Frontiers in Public Health.
[3] Yuejin Li,et al. EZH2 Regulates ANXA6 Expression via H3K27me3 and Is Involved in Angiotensin II-Induced Vascular Smooth Muscle Cell Senescence , 2022, Oxidative medicine and cellular longevity.
[4] Z. Qin,et al. Persistence behavior of chlorpyrifos and biological toxicity mechanism to cucumbers under greenhouse conditions. , 2022, Ecotoxicology and environmental safety.
[5] Junhao Hu,et al. Conditional overexpression of neuritin in supporting cells (SCs) mitigates hair cell (HC) damage and induces HC regeneration in the adult mouse cochlea after drug-induced ototoxicity , 2022, Hearing Research.
[6] Wenping Xu,et al. Evaluation of toxicological effects of organophosphorus pesticide metabolites on human HepG2 cells. , 2021, Environmental toxicology and pharmacology.
[7] Yongzhi Liu,et al. Polyphyllin D induces apoptosis and protective autophagy in breast cancer cells through JNK1-Bcl-2 pathway. , 2021, Journal of ethnopharmacology.
[8] Jinwang Li,et al. 3,5,6-trichloro-2-pyridinol intensifies the effect of chlorpyrifos on the paracrine function of Sertoli cells by preventing binding of testosterone and the androgen receptor. , 2021, Toxicology.
[9] Ying Li,et al. Advanced Oxidation Protein Products Induce G1/G0-Phase Arrest in Ovarian Granulosa Cells via the ROS-JNK/p38 MAPK-p21 Pathway in Premature Ovarian Insufficiency , 2021, Oxidative medicine and cellular longevity.
[10] Jianli Liu,et al. Cadmium induced BEAS-2B cells apoptosis and mitochondria damage via MAPK signaling pathway. , 2021, Chemosphere.
[11] P. Bhatt,et al. Insights into the microbial degradation and catalytic mechanisms of chlorpyrifos. , 2020, Environmental research.
[12] B. Jaramillo-Colorado,et al. Cytotoxic and estrogenic activity of chlorpyrifos and its metabolite 3,5,6-trichloro-2-pyridinol. Study of marine yeasts as potential toxicity indicators , 2020, Ecotoxicology.
[13] R. Salvi,et al. Hydroxypropyl-β-cyclodextrin causes massive damage to the developing auditory and vestibular system , 2020, Hearing Research.
[14] Jianying Zhou,et al. Dioscin facilitates ROS-induced apoptosis via the p38-MAPK/HSP27-mediated pathways in lung squamous cell carcinoma , 2020, International journal of biological sciences.
[15] O. Mehrpour,et al. Oxidative stress and mitochondrial dysfunction in organophosphate pesticide-induced neurotoxicity and its amelioration: a review , 2020, Environmental Science and Pollution Research.
[16] José M. López,et al. Understanding MAPK Signaling Pathways in Apoptosis , 2020, International journal of molecular sciences.
[17] S. Shan,et al. Ferulic acid attenuates oxidative DNA damage and inflammatory responses in microglia induced by benzo(a)pyrene. , 2019, International immunopharmacology.
[18] S. H. Bennekou. Updated statement on the available outcomes of the human health assessment in the context of the pesticides peer review of the active substance chlorpyrifos‐methyl , 2019, EFSA journal. European Food Safety Authority.
[19] D. Theil,et al. Gamma‐H2AX immunofluorescence for the detection of tissue‐specific genotoxicity in vivo , 2018, Environmental and molecular mutagenesis.
[20] R. Salvi,et al. Paraquat initially damages cochlear support cells leading to anoikis-like hair cell death , 2018, Hearing Research.
[21] D. Tucci,et al. Global Hearing Loss Prevention. , 2018, Otolaryngologic clinics of North America.
[22] Ya-min Li,et al. Ascorbic acid inhibits cadmium-induced disruption of the blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways , 2018, Environmental Science and Pollution Research.
[23] D. Ruden,et al. Chronic lead exposure induces cochlear oxidative stress and potentiates noise-induced hearing loss. , 2018, Toxicology letters.
[24] Xiaoxv Dong,et al. Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway , 2018, Toxins.
[25] N. Kaciroti,et al. Prenatal organophosphate insecticide exposure and infant sensory function. , 2018, International journal of hygiene and environmental health.
[26] J. Lemasters,et al. Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells☆ , 2018, Biochemical pharmacology.
[27] Sharon G. Kujawa,et al. Cochlear synaptopathy in acquired sensorineural hearing loss: Manifestations and mechanisms , 2017, Hearing Research.
[28] R. Salvi,et al. Carbaryl‐induced ototoxicity in rat postnatal cochlear organotypic cultures , 2017, Environmental toxicology.
[29] A. Fetoni,et al. Styrene enhances the noise induced oxidative stress in the cochlea and affects differently mechanosensory and supporting cells. , 2016, Free radical biology & medicine.
[30] N. Kopjar,et al. Cytotoxic, genotoxic and biochemical markers of insecticide toxicity evaluated in human peripheral blood lymphocytes and an HepG2 cell line. , 2016, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[31] X. Mai,et al. Prenatal exposure to multiple pesticides is associated with auditory brainstem response at 9months in a cohort study of Chinese infants. , 2016, Environment international.
[32] Channy Park,et al. HEI-OC1 cells as a model for investigating drug cytotoxicity , 2016, Hearing Research.
[33] H. Ren,et al. Hepatotoxicity and nephrotoxicity induced by the chlorpyrifos and chlorpyrifos-methyl metabolite, 3,5,6-trichloro-2-pyridinol, in orally exposed mice. , 2016, The Science of the total environment.
[34] M. Hyppolito,et al. Morphological analysis of the vestibular system of guinea pigs poisoned by organophosphate , 2015, Brazilian journal of otorhinolaryngology.
[35] P. Hollenberg,et al. Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos. , 2015, Chemical research in toxicology.
[36] C. Dinh,et al. Molecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma , 2015, Front. Cell. Neurosci..
[37] C. Fujimoto,et al. Reactive Oxygen Species, Apoptosis, and Mitochondrial Dysfunction in Hearing Loss , 2015, BioMed research international.
[38] M. Abdollahi,et al. In vitro protection of human lymphocytes from toxic effects of chlorpyrifos by selenium-enriched medicines , 2015, Iranian journal of basic medical sciences.
[39] S. Ru,et al. Induction of DNA base damage and strand breaks in peripheral erythrocytes and the underlying mechanism in goldfish (Carassius auratus) exposed to monocrotophos , 2015, Fish Physiology and Biochemistry.
[40] C. Steele,et al. Cytoarchitecture of the Mouse Organ of Corti from Base to Apex, Determined Using In Situ Two-Photon Imaging , 2015, Journal of the Association for Research in Otolaryngology.
[41] Jun Wang,et al. The enzyme toxicity and genotoxicity of chlorpyrifos and its toxic metabolite TCP to zebrafish Danio rerio , 2014, Ecotoxicology.
[42] G. Gajski,et al. γ-H2AX as a biomarker for DNA double-strand breaks in ecotoxicology. , 2014, Ecotoxicology and environmental safety.
[43] R. Salvi,et al. Cadmium-Induced Ototoxicity in Rat Cochlear Organotypic Cultures , 2014, Neurotoxicity Research.
[44] L. Cunningham,et al. Lead roles for supporting actors: Critical functions of inner ear supporting cells , 2013, Hearing Research.
[45] H. Koh,et al. JNK and p38 MAPK regulate oxidative stress and the inflammatory response in chlorpyrifos-induced apoptosis. , 2013, Toxicology letters.
[46] K. Sinha,et al. Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis , 2013, Archives of Toxicology.
[47] G. Zhong,et al. Biodegradation of Chlorpyrifos and Its Hydrolysis Product 3,5,6-Trichloro-2-Pyridinol by a New Fungal Strain Cladosporium cladosporioides Hu-01 , 2012, PloS one.
[48] M. Abdollahi,et al. Protective effect of NAC against malathion-induced oxidative stress in freshly isolated rat hepatocytes. , 2012, Advanced pharmaceutical bulletin.
[49] M. Ramya,et al. Efficiency of the intestinal bacteria in the degradation of the toxic pesticide, chlorpyrifos , 2012, 3 Biotech.
[50] S. Kashanian,et al. DNA binding studies of 3, 5, 6-trichloro-2-pyridinol pesticide metabolite. , 2012, DNA and cell biology.
[51] F. Martı́nez-Soriano,et al. Efficacy of three drugs for protecting against gentamicin‐induced hair cell and hearing losses , 2012, British journal of pharmacology.
[52] Howard Hu,et al. Association between urinary 3, 5, 6-trichloro-2-pyridinol, a metabolite of chlorpyrifos and chlorpyrifos-methyl, and serum T4 and TSH in NHANES 1999-2002. , 2012, The Science of the total environment.
[53] Subash C. Gupta,et al. Chlorpyrifos induces apoptosis and DNA damage in Drosophila through generation of reactive oxygen species. , 2010, Ecotoxicology and environmental safety.
[54] J. Hoppin,et al. Hearing Loss Among Licensed Pesticide Applicators in the Agricultural Health Study , 2008, Journal of occupational and environmental medicine.
[55] J. Loscalzo,et al. Role of oxidative stress and nitric oxide in atherothrombosis. , 2008, Frontiers in bioscience : a journal and virtual library.
[56] G. Pedraza-Alva,et al. p38 Mitogen-Activated Protein Kinase Mediates the Fas-Induced Mitochondrial Death Pathway in CD8+ T Cells , 2006, Molecular and Cellular Biology.
[57] L. Costa,et al. Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. , 2005, Toxicology.
[58] Linda S Sheldon,et al. Exposures of preschool children to chlorpyrifos and its degradation product 3,5,6-trichloro-2-pyridinol in their everyday environments , 2005, Journal of Exposure Analysis and Environmental Epidemiology.
[59] M. Dellarco,et al. Comparative analysis of passive dosimetry and biomonitoring for assessing chlorpyrifos exposure in pesticide workers. , 2004, The Annals of occupational hygiene.
[60] Z. Xia,et al. Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.
[61] D. Lim,et al. A Cochlear Cell Line as an in vitro System for Drug Ototoxicity Screening , 2003, Audiology and Neurotology.
[62] K. Armbrust. Chlorothalonil and chlorpyrifos degradation products in golf course leachate. , 2001, Pest management science.
[63] Z. Xia,et al. Arsenite-Induced Apoptosis in Cortical Neurons Is Mediated by c-Jun N-Terminal Protein Kinase 3 and p38 Mitogen-Activated Protein Kinase , 2000, The Journal of Neuroscience.
[64] D. Kioussis,et al. Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[65] R. Tice,et al. A simple technique for quantitation of low levels of DNA damage in individual cells. , 1988, Experimental cell research.
[66] F. van Breukelen,et al. Effects of chlorpyrifos and trichloropyridinol on HEK 293 human embryonic kidney cells. , 2018, Chemosphere.
[67] V. Ashok Murthy,et al. Audiological Assessment in Organophosphorus Compound Poisoning , 2012, Indian Journal of Otolaryngology and Head & Neck Surgery.
[68] Melanie M. Choe,et al. The comet assay: a method to measure DNA damage in individual cells , 2006, Nature Protocols.
[69] R R Tice,et al. Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop. , 2003, Mutagenesis.