A component-based framework for molecular robotic development as smart drug system

This paper presents a component-based framework for molecular robotic development. We proposed a new model for dynamic structural DNA nanotechnology, based on component for development of molecular robotics which parts can be composed, decomposed and replaced. Moreover, the molecular robotics model is designed to function as a drug delivery system. Molecular robots are structured from DNA, RNA, gels, and enzymes and include five components: the main body and the sensing, processing, actuating, and drug release components. We simulate the components and the framework mechanisms using Nucleic Acid Package software, Visual DNA strand displacement simulation, CadNano and Computer-aided engineering for DNA Origami.