Which objective emergency department parameters leads to expedited intervention in patients with acute urinary tract calculi

Abstract Objectives: To retrospectively determine which objective measurements had an increased likelihood of requiring immediate surgical intervention in patients presenting to the emergency department (ED) with acute ureteral calculi. Materials and methods: Employing our institution's electronic medical record system, we conducted a retrospective cohort study of 4366 patients who presented to the ED with an acute ureteral calculus over an 8-year period. Data consisting of relevant demographic information, vital signs, laboratory parameters, and interventional history was obtained and analyzed. Results: This study consisted of 4366 patients presenting to the ED with acute ureteral calculi, of whom 312 (7%) required a procedure prior to being discharged. Of these 312 patients, 290 (6.6%) underwent cystoscopy with ureteral stent placement and 22 (0.5%) were sent to interventional radiology for percutaneous nephrostomy tube placement. Patients who tested positive for nitrites in their urine had a relative risk of 3.48 of receiving intervention when compared to the nitrite negative group. Conclusions: Through this retrospective cohort study, we were able to find what objective measurements were associated with an increased need for immediate surgical intervention in patients who presented to the ED with acute ureteral calculi. With this data, urologists can be better equipped to identify the patients that present in the emergency setting that will require urgent intervention.

[1]  G. Steinhardt,et al.  Which Objective Parameters Are Associated with a Positive Urine Culture in the Setting of Ureteral Calculi: The Ureteral Calculi Urinary Culture Calculator. , 2018, Journal of endourology.

[2]  A. Kambadakone,et al.  Emergency Ureteral Stone Treatment Score Predicts Outcomes of Ureteroscopic Intervention in Acute Obstructive Uropathy Secondary to Urolithiasis. , 2017, Journal of endourology.

[3]  M. Pearle,et al.  Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART I. , 2016, The Journal of urology.

[4]  G. Preminger,et al.  Emergent ureteric stent vs percutaneous nephrostomy for obstructive urolithiasis with sepsis: patterns of use and outcomes from a 15‐year experience , 2013, BJU international.

[5]  Adam C. Mues,et al.  Surgical decompression is associated with decreased mortality in patients with sepsis and ureteral calculi. , 2013, The Journal of urology.

[6]  Christopher S Saigal,et al.  Prevalence of kidney stones in the United States. , 2012, European urology.

[7]  L. Melton,et al.  Effect of age on the clinical presentation of incident symptomatic urolithiasis in the general population. , 2012, The Journal of urology.

[8]  J. Henny,et al.  Reference intervals for serum creatinine concentrations: assessment of available data for global application. , 2008, Clinical chemistry.

[9]  A. Kessels,et al.  Evaluation of the nitrite and leukocyte esterase activity tests for the diagnosis of acute symptomatic urinary tract infection in men. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[10]  C. Roehrborn,et al.  Optimal method of urgent decompression of the collecting system for obstruction and infection due to ureteral calculi. , 1998, The Journal of urology.

[11]  W. Knaus,et al.  Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. , 1992, Chest.

[12]  R. Bone,et al.  Gram-negative sepsis. Background, clinical features, and intervention. , 1991, Chest.

[13]  K Hoeg,et al.  [Kidney stones]. , 1968, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.