α3-Fucosyltransferase-VI (FUT6)

[1]  V. Wray,et al.  In vitro α1-3 or α1-4 fucosylation of type I and II oligosaccharides with secreted forms of recombinant human fucosyltransferases III and VI , 1998, Glycoconjugate Journal.

[2]  W. van Dijk,et al.  Sialyl Lewisx epitopes do not occur on acute phase proteins in mice: relationship to the absence of α3-fucosyltransferase in the liver , 1998, Glycoconjugate Journal.

[3]  E. B. D. Brinkman-van der Linden,et al.  Inflammation-induced expression of sialyl Lewisx is not restricted to α1-acid glycoprotein but also occurs to a lesser extent on α1-antichymotrypsin and haptoglobin , 1998, Glycoconjugate Journal.

[4]  R. Kannagi.  Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer , 1997, Glycoconjugate Journal.

[5]  A. Donald,et al.  Purification, properties and possible gene assignment of an α1,3-fucosyltransferase expressed in human liver , 1995, Glycoconjugate Journal.

[6]  T. Hada,et al.  Increased plasma α (1 → 3)-l-fucosyltransferase activities in patients with hepatocellular carcinoma , 1995, Glycoconjugate Journal.

[7]  T. Irimura,et al.  A Remodeling System of the 3′-Sulfo-Lewis a and 3′-Sulfo-Lewis x Epitopes* , 2001, The Journal of Biological Chemistry.

[8]  P. Bross,et al.  The C-terminal N-glycosylation sites of the human alpha1,3/4-fucosyltransferase III, -V, and -VI (hFucTIII, -V, adn -VI) are necessary for the expression of full enzyme activity. , 2000, Glycobiology.

[9]  R. Oriol,et al.  FUT4 and FUT9 genes are expressed early in human embryogenesis. , 2000, Glycobiology.

[10]  E. Berger,et al.  Localization of α1,3-fucosyltransferase VI in Weibel–Palade bodies of human endothelial cells , 2000 .

[11]  K. Senger,et al.  Transfection of α(1,3)fucosyltransferase antisense sequences impairs the proliferative and tumorigenic ability of human colon carcinoma cells , 2000 .

[12]  P. Schlag,et al.  Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases , 2000, Gut.

[13]  T. Nishi,et al.  Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer. , 2000, Cancer research.

[14]  E. Berger,et al.  Expression of functional soluble forms of human beta-1, 4-galactosyltransferase I, alpha-2,6-sialyltransferase, and alpha-1, 3-fucosyltransferase VI in the methylotrophic yeast Pichia pastoris. , 2000, Biochemical and biophysical research communications.

[15]  R. Suzuki,et al.  Molecular cloning of a novel CC chemokine, interleukin‐11 receptor α‐locus chemokine (ILC), which is located on chromosome 9p13 and a potential homologue of a CC chemokine encoded by molluscum contagiosum virus , 1999, FEBS letters.

[16]  E. Berger,et al.  alpha1,3Fucosyltransferase VI is expressed in HepG2 cells and codistributed with beta1,4galactosyltransferase I in the golgi apparatus and monensin-induced swollen vesicles. , 1999, Glycobiology.

[17]  R. Cummings,et al.  A Novel Glycosulfopeptide Binds to P-selectin and Inhibits Leukocyte Adhesion to P-selectin* , 1999, The Journal of Biological Chemistry.

[18]  P. Schlag,et al.  Altered mRNA expression of glycosyltransferases in human gastric carcinomas. , 1999, Biochimica et biophysica acta.

[19]  Y. Koda,et al.  Allelic diversity of the human plasma α(1,3)fucosyltransferase gene (FUT6) , 1999 .

[20]  E. Holmes,et al.  Analysis of the expression and enzymatic properties of alpha1-->3fucosyltransferase from human lung carcinoma NCI-H69 and PC9 cells. , 1999, Glycobiology.

[21]  N. Kochibe,et al.  Plasma α1,3-Fucosyltransferase Deficiency in Schizophrenia , 1999, Experimental and Clinical Immunogenetics.

[22]  J. Cusack,et al.  Expression of Human α(1,3)Fucosyltransferase Antisense Sequences Inhibits Selectin-mediated Adhesion and Liver Metastasis of Colon Carcinoma Cells , 1999 .

[23]  R Mollicone,et al.  Divergent evolution of fucosyltransferase genes from vertebrates, invertebrates, and bacteria. , 1999, Glycobiology.

[24]  E. Holmes,et al.  Human α1,3/4-Fucosyltransferases , 1998, The Journal of Biological Chemistry.

[25]  S. Shetterly,et al.  Human alpha1,3/4-fucosyltransferases. I. Identification of amino acids involved in acceptor substrate binding by site-directed mutagenesis. , 1998, The Journal of biological chemistry.

[26]  M. Marcinko,et al.  Human alpha1,3/4-fucosyltransferases. II. A single amino acid at the COOH terminus of FucT III and V alters their kinetic properties. , 1998, The Journal of biological chemistry.

[27]  D. Lombardo,et al.  Fucosyltransferase activities in human pancreatic tissue: comparative study between cancer tissues and established tumoral cell lines. , 1998, Glycobiology.

[28]  R. Kannagi,et al.  Gene expression of fucosyl- and sialyl-transferases which synthesize sialyl Lewisx, the carbohydrate ligands for E-selectin, in human breast cancer. , 1998, International journal of oncology.

[29]  R. Kannagi,et al.  Identification of a Major Carbohydrate Capping Group of the L-selectin Ligand on High Endothelial Venules in Human Lymph Nodes as 6-Sulfo Sialyl Lewis X* , 1998, The Journal of Biological Chemistry.

[30]  E. Berger,et al.  Trafficking and localization studies of recombinant alpha1, 3-fucosyltransferase VI stably expressed in CHO cells. , 1998, Glycobiology.

[31]  M. Costache,et al.  Evolution of Fucosyltransferase Genes in Vertebrates* , 1997, The Journal of Biological Chemistry.

[32]  D. Joziasse,et al.  Acceptor specificity of GDP-Fuc:Galβ1→4GlcNAc-R α3-fucosyltransferase VI (FucT VI) expressed in insect cells as soluble, secreted enzyme , 1997 .

[33]  M. Costache,et al.  Advances in molecular genetics of a-2- and a-3/4-fucosyltransferases , 1997 .

[34]  R. Kannagi,et al.  Altered mRNA expression of specific molecular species of fucosyl‐ and sialyl‐transferases in human colorectal cancer tissues , 1997, International journal of cancer.

[35]  J. Lowe.  Selectin ligands, leukocyte trafficking, and fucosyltransferase genes. , 1997, Kidney international.

[36]  M. Costache,et al.  Molecular Cloning and Expression of a Bovine α(1,3)-Fucosyltransferase Gene Homologous to a Putative Ancestor Gene of the Human FUT3-FUT5-FUT6 Cluster* , 1997, The Journal of Biological Chemistry.

[37]  M. Bird,et al.  Chemical modification of an alpha 3-fucosyltransferase; definition of amino acid residues essential for enzyme activity. , 1997, Biochimica et biophysica acta.

[38]  S. Hung,et al.  Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack. , 1997, Biochemistry.

[39]  伊藤 浩明.  Altered mRNA expression of specific molecular species of fucosyl- and sialyltransferases in human colorectal cancer tissues , 1997 .

[40]  R. Oriol,et al.  Identification of a New Plasma α(1,3)Fucosyltransferase (FUT6) Allele Requires an Extended Genotyping Strategy , 1996, Vox sanguinis.

[41]  Chi‐Huey Wong,et al.  Mechanism and specificity of human α-1,3-fucosyltransferase V , 1996 .

[42]  R. Dicioccio,et al.  Specificity analysis of three clonal and five non-clonal alpha 1,3-L-fucosyltransferases with sulfated, sialylated, or fucosylated synthetic carbohydrates as acceptors in relation to the assembly of 3'-sialyl-6'-sulfo Lewis x (the L-selectin ligand) and related complex structures. , 1996, Biochemistry.

[43]  W. Dippold,et al.  α(1,3)Fucosyltransferase expression in E‐selectin‐mediated binding of gastrointestinal tumor cells , 1996, International journal of cancer.

[44]  R. Oriol,et al.  A Missense Mutation in the FUT6 Gene Results in Total Absence of α3-Fucosylation of Human α1-Acid Glycoprotein* , 1996, The Journal of Biological Chemistry.

[45]  E. Berger,et al.  Immunodetection of alpha 1-3 fucosyltransferase (FucT-V). , 1996, European journal of cell biology.

[46]  Z. Xu,et al.  Structure-function analysis of human alpha1,3-fucosyltransferase. Amino acids involved in acceptor substrate specificity. , 1996, The Journal of biological chemistry.

[47]  A. Nagpurkar,et al.  Characterization and purification of fucosyltransferases from the cytosol of rat colon. , 1996, The international journal of biochemistry & cell biology.

[48]  S. Raychoudhury,et al.  Glycosidic specificity of fucosyltransferases present in rat epididymal spermatozoa. , 1995, Journal of andrology.

[49]  J. Lowe,et al.  Human α(1,3/1,4)-Fucosyltransferases Discriminate between Different Oligosaccharide Acceptor Substrates through a Discrete Peptide Fragment (*) , 1995, The Journal of Biological Chemistry.

[50]  B. Weston,et al.  Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms. , 1995, The Journal of biological chemistry.

[51]  K. Wirtz,et al.  A Sphingomyelin-transferring Protein from Chicken Liver. USE OF PYRENE-LABELED PHOSPHOLIPID (*) , 1995, The Journal of Biological Chemistry.

[52]  M. Palcic,et al.  Acceptor specificity of different length constructs of human recombinant alpha 1,3/4-fucosyltransferases. Replacement of the stem region and the transmembrane domain of fucosyltransferase V by protein A results in an enzyme with GDP-fucose hydrolyzing activity. , 1995, The Journal of biological chemistry.

[53]  Z. Xu,et al.  Structure-function analysis of human alpha 1-->3fucosyltransferases. A GDP-fucose-protected, N-ethylmaleimide-sensitive site in FucT-III and FucT-V corresponds to Ser178 in FucT-IV. , 1995, The Journal of biological chemistry.

[54]  A. Olsen,et al.  Physical maps of human α(1,3)fucosyltransferase genes FUT3–FUT6 on chromosomes 19p13.3 and 11q21 , 1995 .

[55]  R. Oriol,et al.  Detection and Characterization of Lewis Antigens in Plasma of Lewis‐Negative Individuals Evidence of Chain Extension as a Result of Reduced Fucosyltransferase Competition , 1994, Vox sanguinis.

[56]  R. Kannagi,et al.  Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant. , 1994, The Journal of biological chemistry.

[57]  K. Sasaki,et al.  Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes. , 1994, The Journal of biological chemistry.

[58]  R. Oriol,et al.  Molecular basis for plasma α(1,3)-fucosyltransferase gene deficiency (FUT6) , 1994 .

[59]  S. Yamamoto,et al.  Fucosyltransferase‐producing sialyl Lea and sialyl Lex carbohydrate antigen in benign and malignant gastrointestinal mucosa , 1994, Cancer.

[60]  G. Walz,et al.  A sialyl-Le(x)-negative melanoma cell line binds to E-selectin but not to P-selectin. , 1994, Cancer research.

[61]  R. Jain,et al.  Lactose as affinity eluent and a synthetic sulfated copolymer as inhibitor, in conjunction with synthetic and natural acceptors, differentiate human milk Lewis-type and plasma-type alpha-L-fucosyltransferases. , 1994, Biochemical and biophysical research communications.

[62]  R. Oriol,et al.  Detection and Characterization of Lewis Antigens in Plasma of Lewis-Negative Individuals , 1994 .

[63]  R. Kannagi,et al.  Expression of alpha-(1,3)-fucosyltransferases which synthesize sialyl Le(x) and sialyl Le(a), the carbohydrate ligands for E- and P-selectins,in human malignant cell lines. , 1993, Cancer research.

[64]  R. Oriol,et al.  Alpha-3-fucosyltransferases and their glycoconjugate antigen products in the developing human kidney. , 1993, Laboratory investigation; a journal of technical methods and pathology.

[65]  D. H. van den Eijnden,et al.  Efficient enzymatic synthesis of the sialyl‐LewisX tetrasaccharide , 1993, FEBS letters.

[66]  W. van Dijk,et al.  Inflammation-induced expression of sialyl Lewis X-containing glycan structures on alpha 1-acid glycoprotein (orosomucoid) in human sera , 1993, The Journal of experimental medicine.

[67]  T. Ando,et al.  Human alpha-1,3 fucosyltransferase (FucT-VI) gene is located at only 13 kb 3' to the Lewis type fucosyltransferase (FucT-III) gene on chromosome 19. , 1993, Biochemical and biophysical research communications.

[68]  R. Kannagi,et al.  Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium. , 1993, Cancer research.

[69]  J. Lowe,et al.  Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. , 1992, The Journal of biological chemistry.

[70]  B. Bowen,et al.  The cloning and expression of a human alpha-1,3 fucosyltransferase capable of forming the E-selectin ligand. , 1992, Biochemical and biophysical research communications.

[71]  J. Lowe,et al.  Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities. , 1992, The Journal of biological chemistry.

[72]  Jamel Chelly,et al.  Illegitimate transcription: Its use in the study of inherited disease , 1992, Human mutation.

[73]  T. Ørntoft,et al.  Lewis Blood Group Antigens in Salivary Glands and Stratified Epithelium: Lack of Regulation of Lewis Antigen Expression in Ductal and Buccal Mucosal Lining Epithelia 1 , 1991, Vox sanguinis.

[74]  R. Kannagi,et al.  Adhesion of human cancer cells to vascular endothelium mediated by a carbohydrate antigen, sialyl Lewis A. , 1991, Biochemical and biophysical research communications.

[75]  S. Thompson,et al.  Changes in fucose metabolism associated with heavy drinking and smoking: a preliminary report. , 1991, Clinica chimica acta; international journal of clinical chemistry.

[76]  M. Du,et al.  Fucosyltransferases: Differential plasma and tissue alterations in hepatocellular carcinoma and cirrhosis , 1991, Hepatology.

[77]  S. Hakomori,et al.  Differential tissue expression of the Lewis blood group antigens: enzymatic, immunohistologic, and immunochemical evidence for Lewis a and b antigen expression in Le(a-b-) individuals. , 1991, Blood.

[78]  A. Gibaud,et al.  Acceptor specificity and tissue distribution of three human α‐3‐fucosyltransferases , 1990 .