Nicotinamide riboside enhances in vitro beta-adrenergic brown adipose tissue activity in humans.
暂无分享,去创建一个
J. Auwerx | W. D. van Marken Lichtenbelt | P. Schrauwen | K. Gariani | G. Schaart | J. Hoeks | J. Jörgensen | E. Nascimento | Michiel P B Moonen | Carlijn M. E. Remie | Emmani B. M. Nascimento
[1] L. Sidossis,et al. Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans. , 2016, Cell metabolism.
[2] M. V. van Gisbergen,et al. Genetic Markers of Brown Adipose Tissue Identity and In Vitro Brown Adipose Tissue Activity in Humans , 2018, Obesity.
[3] Yue Yang,et al. Dihydronicotinamide riboside is a potent NAD+ concentration enhancer in vitro and in vivo , 2019, The Journal of Biological Chemistry.
[4] J. Holst,et al. Effects of nicotinamide riboside on endocrine pancreatic function and incretin hormones in obese, non-diabetic men. , 2019, The Journal of clinical endocrinology and metabolism.
[5] C. Müller,et al. Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors , 2014, Nature.
[6] Felix M Mottaghy,et al. Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. , 2013, The Journal of clinical investigation.
[7] B. Spiegelman,et al. A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat , 2015, Cell.
[8] Nallely López-López,et al. Altered levels of sirtuin genes (SIRT1, SIRT2, SIRT3 and SIRT6) and their target genes in adipose tissue from individual with obesity. , 2019, Diabetes & metabolic syndrome.
[9] F. Mottaghy,et al. The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity. , 2015, Cell metabolism.
[10] A. Palou,et al. Programming of the Beige Phenotype in White Adipose Tissue of Adult Mice by Mild Resveratrol and Nicotinamide Riboside Supplementations in Early Postnatal Life , 2018, Molecular nutrition & food research.
[11] Johan Auwerx,et al. Sirtuins as regulators of metabolism and healthspan , 2012, Nature Reviews Molecular Cell Biology.
[12] S. Schmid,et al. Cold‐Induced Brown Adipose Tissue Activity Alters Plasma Fatty Acids and Improves Glucose Metabolism in Men , 2017, The Journal of clinical endocrinology and metabolism.
[13] F. Villarroya,et al. Beyond the sympathetic tone: the new brown fat activators. , 2013, Cell metabolism.
[14] M. Miyagawa,et al. High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans , 2009, Diabetes.
[15] Jan Nedergaard,et al. Brown adipose tissue: function and physiological significance. , 2004, Physiological reviews.
[16] A. Doria,et al. Activation of human brown adipose tissue by a β3-adrenergic receptor agonist. , 2015, Cell metabolism.
[17] J. Baur,et al. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. , 2017, Cell metabolism.
[18] F. Mottaghy,et al. Brown adipose tissue activity after a high-calorie meal in humans. , 2013, The American journal of clinical nutrition.
[19] P. Puigserver,et al. Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α , 2006, Cell.
[20] A. Sauve,et al. Syntheses of nicotinamide riboside and derivatives: effective agents for increasing nicotinamide adenine dinucleotide concentrations in mammalian cells. , 2007, Journal of medicinal chemistry.
[21] J. Auwerx,et al. Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans , 2020, The American journal of clinical nutrition.
[22] Mark S. Schmidt,et al. A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects. , 2018, The American journal of clinical nutrition.
[23] J. Auwerx,et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation , 2006, Nature.
[24] J. Auwerx,et al. Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice , 2015, Hepatology.
[25] J. Auwerx,et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. , 2012, Cell metabolism.
[26] A. Hsueh,et al. Increasing ovarian NAD+ levels improve mitochondrial functions and reverse ovarian aging. , 2020, Free radical biology & medicine.
[27] J. Treebak,et al. Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin‐resistant men , 2019, The Journal of physiology.
[28] R. Zechner,et al. Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice. , 2018, Cell metabolism.
[29] J. Auwerx,et al. Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity , 2017, Nature.
[30] C. Brenner,et al. Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder , 2020, Scientific Reports.
[31] J. Auwerx,et al. Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3 , 2014, EMBO molecular medicine.
[32] J. Orava,et al. Functional brown adipose tissue in healthy adults. , 2009, The New England journal of medicine.
[33] R. Aebersold,et al. NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice , 2016, Science.
[34] Mami Matsushita,et al. Recruited brown adipose tissue as an antiobesity agent in humans. , 2013, The Journal of clinical investigation.
[35] F. Mottaghy,et al. Short-term Cold Acclimation Recruits Brown Adipose Tissue in Obese Humans , 2015, Diabetes.
[36] J. Auwerx,et al. NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. , 2015, Cell metabolism.
[37] J. Orava,et al. Different metabolic responses of human brown adipose tissue to activation by cold and insulin. , 2011, Cell metabolism.
[38] Yu-cai Fu,et al. Direct evidence of sirtuin downregulation in the liver of non-alcoholic fatty liver disease patients. , 2014, Annals of clinical and laboratory science.
[39] E. Palmer,et al. Identification and importance of brown adipose tissue in adult humans. , 2009, The New England journal of medicine.
[40] S. Kajimura,et al. UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis , 2017, Nature Medicine.
[41] Mark S. Schmidt,et al. Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity‐induced axonal degeneration , 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[42] B. Spiegelman,et al. Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human , 2012, Cell.
[43] J. Auwerx,et al. NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation , 2016, Science Translational Medicine.
[44] E. Verdin. NAD+ in aging, metabolism, and neurodegeneration , 2015, Science.
[45] W. D. van Marken Lichtenbelt,et al. Cold-activated brown adipose tissue in healthy men. , 2009, The New England journal of medicine.
[46] E. Ropelle,et al. Nicotinamide riboside induces a thermogenic response in lean mice , 2018, Life sciences.
[47] B. Pedersen,et al. A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans. , 2013, Cell metabolism.
[48] R. Kardon,et al. Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice , 2016, Scientific Reports.