Phytotherapy and food applications from Brassica genus

Plants of the genus Brassica occupy the top place among vegetables in the world. This genus, which contains a group of six related species of a global economic significance, three of which are diploid: Brassica nigra (L.) K. Koch, Brassica oleracea L., and Brassica rapa L. and three are amphidiploid species: Brassica carinata A. Braun, Brassica juncea (L.) Czern., and Brassica napus L. These varieties are divided into oily, fodder, spice, and vegetable based on their morphological structure, chemical composition, and usefulness of plant organs. The present review provides information about habitat, phytochemical composition, and the bioactive potential of Brassica plants, mainly antioxidant, antimicrobial, anticancer activities, and clinical studies in human. Brassica vegetables are of great economic importance around the world. At present, Brassica plants are grown together with cereals and form the basis of global food supplies. They are distinguished by high nutritional properties from other vegetable plants, such as low fat and protein content and high value of vitamins, fibers along with minerals. In addition, they possess several phenolic compounds and have a unique type of compounds namely glucosinolates that differentiate these crops from other vegetables. These compounds are also responsible for numerous biological activities to the genus Brassica as described in this review.

[1]  F. Di Gioia,et al.  Glucosinolates , 2021, Food Bioactives and Health.

[2]  Shriya Bhatt,et al.  Antioxidant and prebiotic potential of Murraya koenigii and Brassica oleracea var. botrytis leaves as food ingredient , 2020 .

[3]  C. Houston-Price,et al.  The Relationship between Glucosinolates and the Sensory Characteristics of Steamed-Pureed Turnip (Brassica Rapa subsp. Rapa L.) , 2020, Foods.

[4]  O. Hur,et al.  Glucosinolate Content in Brassica Genetic Resources and Their Distribution Pattern within and between Inner, Middle, and Outer Leaves , 2020, Plants.

[5]  A. Camargo,et al.  Phytochemical profile and functionality of Brassicaceae species , 2020 .

[6]  Jai-Sing Yang,et al.  Potential effects of allyl isothiocyanate on inhibiting cellular proliferation and inducing apoptotic pathway in human cisplatin-resistant oral cancer cells. , 2020, Journal of the Formosan Medical Association = Taiwan yi zhi.

[7]  K. Ohba,et al.  Molecular Mechanisms of the Anti-Cancer Effects of Isothiocyanates from Cruciferous Vegetables in Bladder Cancer , 2020, Molecules.

[8]  M. G. Collett,et al.  Investigating the cause of Brassica-associated liver disease (BALD) in cattle: Progoitrin-derived nitrile toxicosis in rats , 2019, Toxicon: X.

[9]  Bo Sun,et al.  Health-promoting phytochemicals and antioxidant capacity in different organs from six varieties of Chinese kale , 2019, Scientific Reports.

[10]  U. Sohn,et al.  Benzyl Isothiocyanate Induces Apoptosis via Reactive Oxygen Species-Initiated Mitochondrial Dysfunction and DR4 and DR5 Death Receptor Activation in Gastric Adenocarcinoma Cells , 2019, Biomolecules.

[11]  C. Chiu,et al.  Broccoli (Brassica oleracea L. var. italica) Sprouts as the Potential Food Source for Bioactive Properties: A Comprehensive Study on In Vitro Disease Models , 2019, Foods.

[12]  H. Çubukçu,et al.  Different effects of heating and freezing treatments on the antioxidant properties of broccoli, cauliflower, garlic and onion. An experimental in vitro study , 2019, Sao Paulo medical journal = Revista paulista de medicina.

[13]  A. Bartoszek,et al.  Phytochemical composition and biological activities of differently pigmented cabbage (Brassica oleracea var. capitata) and cauliflower (Brassica oleracea var. botrytis) varieties. , 2019, Journal of the science of food and agriculture.

[14]  Y. Chang,et al.  Valorizing cabbage (Brassica oleracea L. var. capitata) and capsicum (Capsicum annuum L.) wastes: in vitro health-promoting activities , 2019, Journal of Food Science and Technology.

[15]  H. Domínguez,et al.  Recovery of aqueous phase of broccoli obtained by MHG technique for development of hydrogels with antioxidant properties , 2019, LWT.

[16]  G. Węgrzyn,et al.  Mechanism of selective anticancer activity of isothiocyanates relies on differences in DNA damage repair between cancer and healthy cells , 2019, European Journal of Nutrition.

[17]  Ho-Young Park,et al.  Rhamnogalacturonan-I-Type Polysaccharide Purified from Broccoli Exerts Anti-Metastatic Activities Via Innate Immune Cell Activation. , 2019, Journal of medicinal food.

[18]  Fenghong Huang,et al.  Primary Metabolites and Polyphenols in Rapeseed (Brassica napus L .) Cultivars in China , 2019, Journal of the American Oil Chemists' Society.

[19]  Yuan Li,et al.  Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway , 2019, International journal of food sciences and nutrition.

[20]  G. Ribaudo,et al.  HPLC and NMR quantification of bioactive compounds in flowers and leaves of Brassica rapa: the influence of aging , 2019, Natural product research.

[21]  A. Zawada,et al.  Amaranth (Amaranthus cruentus L.) and canola (Brassica napus L.) oil impact on the oxidative metabolism of neutrophils in the obese patients* , 2019, Pharmaceutical biology.

[22]  S. Paul,et al.  Phytochemical and Health-Beneficial Progress of Turnip (Brassica rapa). , 2019, Journal of food science.

[23]  A. Mollica,et al.  Polyphenolic composition, enzyme inhibitory effects ex-vivo and in-vivo studies on two Brassicaceae of north-central Italy. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[24]  I. Aguiló‐Aguayo,et al.  Steaming and sous-vide: Effects on antioxidant activity, vitamin C, and total phenolic content of Brassica vegetables , 2018, International Journal of Gastronomy and Food Science.

[25]  F. Luciano,et al.  Combination of garlic essential oil, allyl isothiocyanate, and nisin Z as bio-preservatives in fresh sausage. , 2018, Meat science.

[26]  Jian-Min Yuan,et al.  Isothiocyanates: Translating the Power of Plants to People. , 2018, Molecular nutrition & food research.

[27]  Qi Zhang,et al.  Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β‐catenin pathway , 2018, Phytotherapy research : PTR.

[28]  R. Holley,et al.  Control of Salmonella enterica and Listeria monocytogenes in hummus using allyl isothiocyanate. , 2018, International journal of food microbiology.

[29]  B. Salehi,et al.  Veronica persica Poir. extract - antibacterial, antifungal and scolicidal activities, and inhibitory potential on acetylcholinesterase, tyrosinase, lipoxygenase and xanthine oxidase. , 2018, Cellular and molecular biology.

[30]  B. Salehi,et al.  In vitro and in vivo assessment of free radical scavenging and antioxidant activities of Veronica persica Poir. , 2018, Cellular and molecular biology.

[31]  Anubhuti Sharma,et al.  GC–MS detection and determination of major volatile compounds in Brassica juncea L. leaves and seeds , 2018 .

[32]  C. Sălăvăstru,et al.  Traditional and ethnobotanical dermatology practices in Romania and other Eastern European countries. , 2018, Clinics in dermatology.

[33]  H. Nawaz,et al.  Optimization of extraction yield and antioxidant properties of Brassica oleracea Convar Capitata Var L. leaf extracts. , 2018, Food chemistry.

[34]  R. Azevedo,et al.  Evaluation of the Genotoxic and Antigenotoxic Effects of Andiroba (Carapa guianensis Aublet) Oil and Nanoemulsion on Swiss Mice , 2018 .

[35]  D. Bideshi,et al.  Antimicrobial activity of broccoli (Brassica oleracea var. italica) cultivar Avenger against pathogenic bacteria, phytopathogenic filamentous fungi and yeast , 2018, Journal of applied microbiology.

[36]  Mahmudur Rahman,et al.  Brassicaceae Mustards: Traditional and Agronomic Uses in Australia and New Zealand , 2018, Molecules.

[37]  M. Ghaedi,et al.  Ultrasound assisted extraction of phenolic acids from broccoli vegetable and using sonochemistry for preparation of MOF-5 nanocubes: Comparative study based on micro-dilution broth and plate count method for synergism antibacterial effect. , 2018, Ultrasonics sonochemistry.

[38]  K. Kataoka,et al.  Structural analysis of an innate immunostimulant from broccoli, Brassica oleracea var. italica. , 2017, Drug discoveries & therapeutics.

[39]  K. Baek,et al.  Green biosynthesis of magnetic iron oxide (Fe3O4) nanoparticles using the aqueous extracts of food processing wastes under photo-catalyzed condition and investigation of their antimicrobial and antioxidant activity. , 2017, Journal of photochemistry and photobiology. B, Biology.

[40]  M. Schreiner,et al.  Isothiocyanates, Nitriles, and Epithionitriles from Glucosinolates Are Affected by Genotype and Developmental Stage in Brassica oleracea Varieties , 2017, Front. Plant Sci..

[41]  M. Inoue,et al.  Cruciferous Vegetable Intake Is Inversely Associated with Lung Cancer Risk among Current Nonsmoking Men in the Japan Public Health Center (JPHC) Study. , 2017, The Journal of nutrition.

[42]  F. Di Gioia,et al.  Vegetable Organosulfur Compounds and their Health Promoting Effects. , 2017, Current pharmaceutical design.

[43]  A. Serra,et al.  Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study , 2017, Nutrients.

[44]  J. Hébert,et al.  Effect of Cruciferous Vegetable Intake on Oxidative Stress Biomarkers: Differences by Breast Cancer Status , 2017, Cancer investigation.

[45]  N. Sabaou,et al.  Chemical Variability and Biological Activities of Brassica rapa var. rapifera Parts Essential Oils Depending on Geographic Variation and Extraction Technique , 2017, Chemistry & biodiversity.

[46]  M. Dekker,et al.  Optimizing isothiocyanate formation during enzymatic glucosinolate breakdown by adjusting pH value, temperature and dilution in Brassica vegetables and Arabidopsis thaliana , 2017, Scientific Reports.

[47]  Chun Chen,et al.  Effects of Tibetan turnip (Brassica rapa L.) on promoting hypoxia-tolerance in healthy humans. , 2017, Journal of ethnopharmacology.

[48]  K. G. Ramawat,et al.  Genetics and Breeding of Brassica Crops , 2017 .

[49]  I. Pavlović,et al.  White cabbage (Brassica oleracea var. capitata f. alba): botanical, phytochemical and pharmacological overview , 2017, Phytochemistry Reviews.

[50]  Jihyeung Ju,et al.  Anti-cancer activities of Brassica juncea leaves in vitro , 2016, EXCLI journal.

[51]  A. Tiwari,et al.  Phytochemical screening of red cabbage (Brassica oleracea) powder and juice - A comparative study , 2016 .

[52]  R. Holley,et al.  Inhibition of Listeria monocytogenes on cooked cured chicken breasts by acidified coating containing allyl isothiocyanate or deodorized Oriental mustard extract. , 2016, Food microbiology.

[53]  Muhammad Maqsood Alam,et al.  Documenting the indigenous knowledge on medicinal flora from communities residing near Swat River (Suvastu) and in high mountainous areas in Swat-Pakistan. , 2016, Journal of ethnopharmacology.

[54]  M. Gola,et al.  Irritant contact dermatitis caused by Savoy cabbage , 2016, Contact dermatitis.

[55]  Dharani Mayilsamy,et al.  ANTICANCER STUDY OF HEMATOLOGICAL AND SURVIVAL PERIOD IN BRASSICA RAPA CHINENSIS LINN. USING IN VIVO MODEL IN MICE , 2016 .

[56]  J. Fahey,et al.  Brassica: Characteristics and Properties , 2016 .

[57]  Ashwani Kumar Thukral,et al.  Phytochemical and Elemental Analysis of Brassica juncea L. Leaves using GC-MS and SEM-EDX , 2015 .

[58]  B. Güler,et al.  Contribution to the traditional uses of medicinal plants of Turgutlu (Manisa--Turkey). , 2015, Journal of ethnopharmacology.

[59]  A. López‐Malo,et al.  Antifungal activity of essential oils of clove (Syzygium aromaticum) and/or mustard (Brassica nigra) in vapor phase against gray mold (Botrytis cinerea) in strawberries , 2015 .

[60]  A. P. Vale,et al.  Phytochemical composition and antimicrobial properties of four varieties of Brassica oleracea sprouts , 2015 .

[61]  J. Mañes,et al.  Influence of the antimicrobial compound allyl isothiocyanate against the Aspergillus parasiticus growth and its aflatoxins production in pizza crust. , 2015, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[62]  J. Jo,et al.  Comparison of Glucosinolate Profiles in Different Tissues of Nine Brassica Crops , 2015, Molecules.

[63]  R. K. Manhas,et al.  Ethnomedicinal plants of Kathua district, J&K, India. , 2015, Journal of ethnopharmacology.

[64]  R. Holley,et al.  Control of Salmonella on fresh chicken breasts by κ-carrageenan/chitosan-based coatings containing allyl isothiocyanate or deodorized Oriental mustard extract plus EDTA. , 2015, Food microbiology.

[65]  P. Avato,et al.  Brassicaceae: a rich source of health improving phytochemicals , 2015, Phytochemistry Reviews.

[66]  A. Bekhit,et al.  Microwave and pulsed electric field assisted extractions of polyphenols from defatted canola seed cake , 2015 .

[67]  Priya Sharma,et al.  Biopharmaceutical aspects of Brassica vegetables , 2015 .

[68]  R. Dash,et al.  Effects of organic extracts and their different fractions of five Bangladeshi plants on in vitro thrombolysis , 2015, BMC Complementary and Alternative Medicine.

[69]  M. Buera,et al.  Stabilization of refrigerated avocado pulp: Effect of Allium and Brassica extracts on enzymatic browning , 2015 .

[70]  M. C. Pina-Pérez,et al.  Antimicrobial activity of cauliflower (Brassica oleracea var. Botrytis) by-product against Listeria monocytogenes , 2015 .

[71]  A. López‐Malo,et al.  Composition, diffusion, and antifungal activity of black mustard (Brassica nigra) essential oil when applied by direct addition or vapor phase contact. , 2015, Journal of food protection.

[72]  M. Hosseini,et al.  Effects of aqueous extract of turnip leaf (Brassica rapa) in alloxan-induced diabetic rats , 2015, Avicenna journal of phytomedicine.

[73]  K. Kuchta,et al.  A phytosterol enriched refined extract of Brassica campestris L. pollen significantly improves benign prostatic hyperplasia (BPH) in a rat model as compared to the classical TCM pollen preparation Qianlie Kang Pule'an Tablets. , 2015, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[74]  S. Bhandari,et al.  Chemical Composition and Antioxidant Activity in Different Tissues of Brassica Vegetables , 2015, Molecules.

[75]  J. Shim,et al.  The Effects of Broccoli Sprout Extract Containing Sulforaphane on Lipid Peroxidation and Helicobacter pylori Infection in the Gastric Mucosa , 2014, Gut and liver.

[76]  Ricardo Stefani,et al.  Active chitosan/PVA films with anthocyanins from Brassica oleraceae (Red Cabbage) as Time–Temperature Indicators for application in intelligent food packaging , 2015 .

[77]  T. Tuttolomondo,et al.  Popular uses of wild plant species for medicinal purposes in the Nebrodi Regional Park (North-Eastern Sicily, Italy). , 2014, Journal of ethnopharmacology.

[78]  A. Khanna,et al.  Pharmacognosy and Phytochemical Analysis of Brassica juncea Seeds , 2014 .

[79]  L. Settanni,et al.  Antibacterial activity of Borago officinalis and Brassica juncea aqueous extracts evaluated in vitro and in situ using different food model systems , 2014 .

[80]  Xiaowu Wang,et al.  Genome triplication drove the diversification of Brassica plants , 2014, Horticulture Research.

[81]  B. Stegelmeier,et al.  Could nitrile derivatives of turnip (Brassica rapa) glucosinolates be hepato- or cholangiotoxic in cattle? , 2014, Journal of agricultural and food chemistry.

[82]  M. Miyazawa,et al.  Chemical composition, aroma evaluation, and oxygen radical absorbance capacity of volatile oil extracted from Brassica rapa cv. "yukina" used in Japanese traditional food. , 2014, Journal of oleo science.

[83]  M. Atanassova,et al.  Comparative evaluation of the polyphenol composition and antioxidant capacity of propolis and Echinacea purpurea , 2014 .

[84]  P. Pasalar,et al.  A preliminary investigation of anticholinesterase activity of some Iranian medicinal plants commonly used in traditional medicine , 2014, DARU Journal of Pharmaceutical Sciences.

[85]  R. Thangam,et al.  Antioxidant and In Vitro Anticancer Effect of 2‐Pyrrolidinone Rich Fraction of Brassica oleracea var. capitata Through Induction of Apoptosis in Human Cancer Cells , 2013, Phytotherapy research : PTR.

[86]  F. Abas,et al.  Novel anticancer activity and anticancer mechanisms of Brassica oleracea L. var. capitata f. rubra , 2013 .

[87]  G. Meca,et al.  Antifungal activity of gaseous allyl, benzyl and phenyl isothiocyanate in vitro and their use for fumonisins reduction in bread , 2013 .

[88]  R. Kumar,et al.  New claims in folk veterinary medicines from Uttar Pradesh, India. , 2013, Journal of ethnopharmacology.

[89]  Yi-fang Yang,et al.  Analysis of Hydroxy Fatty Acids from the Pollen of Brassica campestris L. var. oleifera DC. by UPLC-MS/MS , 2012, Journal of pharmaceutics.

[90]  Sung Jin Kim,et al.  Antioxidant and antimicrobial activities of leafy green vegetable extracts and their applications to meat product preservation , 2013 .

[91]  E. L. Maistro,et al.  Evaluation of the genotoxic and antigenotoxic potential of Brassica oleracea L. var. acephala D.C. in different cells of mice. , 2012, Journal of ethnopharmacology.

[92]  M. E. Cartea,et al.  New insights into antioxidant activity of Brassica crops. , 2012, Food chemistry.

[93]  E. Rosa,et al.  GLUCOSINOLATE COMPOSITION OF BRASSICA IS AFFECTED BY POSTHARVEST, FOOD PROCESSING AND MYROSINASE ACTIVITY , 2012 .

[94]  L. Truelstrup Hansen,et al.  Antimicrobial activity of cyclodextrin entrapped allyl isothiocyanate in a model system and packaged fresh-cut onions. , 2012, Food microbiology.

[95]  Sin-Ae Park,et al.  Chemical Composition of the Essential Oil and Petroleum Ether Extract of Brassica napus Seeds , 2012 .

[96]  Documenting Indigenous Knowledge , 2012 .

[97]  J. R. Santin,et al.  Gastroprotective activity of hydroalcoholic extract obtained from the leaves of Brassica oleracea var. acephala DC in different animal models. , 2011, Journal of ethnopharmacology.

[98]  E. Kiarie,et al.  Growth performance, organ weights, and blood parameters of broilers fed diets containing expeller-extracted canola meal. , 2011, Poultry science.

[99]  Jorge Adolfo Silva,et al.  Low soil water content during growth contributes to preservation of green colour and bioactive compounds of cold-stored broccoli (Brassica oleraceae L.) florets , 2011 .

[100]  A. Birch,et al.  Phytochemicals of Brassicaceae in plant protection and human health--influences of climate, environment and agronomic practice. , 2011, Phytochemistry.

[101]  J. Grúz,et al.  Antioxidant potency of white (Brassica oleracea L. var. capitata) and Chinese (Brassica rapa L. var. pekinensis Lour.) cabbage: The influence of development stage, cultivar choice and seed selection , 2011 .

[102]  M. E. Cartea,et al.  Phenolic Compounds in Brassica Vegetables , 2010, Molecules.

[103]  G. Martínez,et al.  Influence of combined hot air and UV-C treatment on the antioxidant system of minimally processed broccoli (Brassica oleracea L. var. Italica) , 2010 .

[104]  N. Chiewchan,et al.  Effect of Processing on Antioxidants and Their Activity in Dietary Fiber Powder from Cabbage Outer Leaves , 2010 .

[105]  M. Cefola,et al.  Effect of atmosphere composition on the quality of ready-to-use broccoli raab (Brassica rapa L.). , 2010, Journal of the science of food and agriculture.

[106]  E. Chiavaro,et al.  Effect of different cooking methods on color, phytochemical concentration, and antioxidant capacity of raw and frozen brassica vegetables. , 2010, Journal of agricultural and food chemistry.

[107]  A. Vig,et al.  Bio-protective effects of glucosinolates - a review. , 2009 .

[108]  Y. Choi,et al.  Health-Affecting Compounds in Brassicaceae , 2009 .

[109]  I. Hyodo,et al.  Dietary Sulforaphane-Rich Broccoli Sprouts Reduce Colonization and Attenuate Gastritis in Helicobacter pylori–Infected Mice and Humans , 2009, Cancer Prevention Research.

[110]  Sueli Rodrigues,et al.  Ultrasound-assisted extraction. , 2009 .

[111]  Z. Iqbal,et al.  An account of the botanical anthelmintics used in traditional veterinary practices in Sahiwal district of Punjab, Pakistan. , 2008, Journal of ethnopharmacology.

[112]  Z. Iqbal,et al.  Ethnoveterinary practices for the treatment of parasitic diseases in livestock in Cholistan desert (Pakistan). , 2008, Journal of ethnopharmacology.

[113]  U. Gawlik‐Dziki Effect of hydrothermal treatment on the antioxidant properties of broccoli (Brassica oleracea var. botrytis italica) florets. , 2008, Food chemistry.

[114]  Gun-Hee Kim,et al.  Anticancer and Antimicrobial Activities of β-Phenylethyl Isothiocyanate in Brassica rapa L. , 2008 .

[115]  R. Kale,et al.  Protective effect of the cruciferous vegetable mustard leaf (Brassica campestris) against in vivo chromosomal damage and oxidative stress induced by γ‐radiation and genotoxic chemicals , 2008, Environmental and molecular mutagenesis.

[116]  Ho Yin Edwin Chan,et al.  Green tea catechins and broccoli reduce fat-induced mortality in Drosophila melanogaster. , 2008, The Journal of nutritional biochemistry.

[117]  Ho Yin Edwin Chan,et al.  Broccoli (Brassica oleracea var. botrytis L.) improves the survival and up‐regulates endogenous antioxidant enzymes in Drosophila melanogaster challenged with reactive oxygen species , 2008 .

[118]  E. Chiavaro,et al.  Effects of different cooking methods on nutritional and physicochemical characteristics of selected vegetables. , 2008, Journal of agricultural and food chemistry.

[119]  Arla,et al.  Phytochemical and Antioxidant Characterization of Brassica oleracea Var . Costata Extracts , 2008 .

[120]  Yi Lou,et al.  A steroid fraction of chloroform extract from bee pollen of Brassica campestris induces apoptosis in human prostate cancer PC‐3 cells , 2007, Phytotherapy research : PTR.

[121]  B. Ernst,et al.  Extraction and analysis of intact glucosinolates--a validated pressurized liquid extraction/liquid chromatography-mass spectrometry protocol for Isatis tinctoria, and qualitative analysis of other cruciferous plants. , 2007, Journal of chromatography. A.

[122]  M. Tripathi,et al.  GLICOSINOLATES IN ANIMAL NUTRITION: A REVIEW , 2007 .

[123]  A. Podsędek Natural antioxidants and antioxidant capacity of Brassica vegetables : A review , 2007 .

[124]  Young A Lee,et al.  Protective effects of broccoli (Brassica oleracea) against oxidative damage in vitro and in vivo. , 2006, Journal of nutritional science and vitaminology.

[125]  A. Yanaka,et al.  [Effects of sulforaphane-rich broccoli sprouts on H. pylori-infected gastric mucosa]. , 2005, Nihon rinsho. Japanese journal of clinical medicine.

[126]  N. Zaffaroni,et al.  Mechanisms of action and antiproliferative properties of Brassica oleracea juice in human breast cancer cell lines. , 2005, The Journal of nutrition.

[127]  P. Civello,et al.  Effect of hot air treatments on senescence and quality parameters of harvested broccoli (Brassica oleracea L var Italica) heads , 2005 .

[128]  I. Babik Nitrogen requirements and fertilization of Brussels sprouts. , 2005 .

[129]  P. Guarrera Traditional phytotherapy in Central Italy (Marche, Abruzzo, and Latium). , 2005, Fitoterapia.

[130]  A. Silverman,et al.  Oral Broccoli Sprouts for the Treatment of Helicobacter pylori Infection: A Preliminary Report , 2004, Digestive Diseases and Sciences.

[131]  S. Seth,et al.  Medicinal plants in India. , 2004, The Indian journal of medical research.

[132]  G. Rakow,et al.  Species Origin and Economic Importance of Brassica , 2004 .

[133]  M. Uehara,et al.  Phase 1 study of multiple biomarkers for metabolism and oxidative stress after one‐week intake of broccoli sprouts , 2004, BioFactors.

[134]  M. Nakashima,et al.  [LDL-cholesterol-lowering effect of a mixed green vegetable and fruit beverage containing broccoli and cabbage in hypercholesterolemic subjects]. , 2003, Rinsho byori. The Japanese journal of clinical pathology.

[135]  Alison Munns Cabbage leaves can help inflammation of any body part , 2003, British medical journal.

[136]  T. Yokozawa,et al.  In Vitro and in vivo antioxidant effects of mustard leaf (Brassica juncea) , 2003, Phytotherapy research : PTR.

[137]  H. Matsui,et al.  Daily intake of sulforaphane-rich broccoli sprouts prevents progression of high salt diet-induced gastric atrophy in H. pylori-infected C57/BL6 mice in vivo , 2003 .

[138]  S. Yadav,et al.  Medicinal plants of India with anti-diabetic potential. , 2002, Journal of ethnopharmacology.

[139]  R. J. Tyrl,et al.  Toxic plants of North America. , 2001 .

[140]  H. S. Hussein,et al.  Toxicity, metabolism, and impact of mycotoxins on humans and animals. , 2001, Toxicology.

[141]  Y. Lee,et al.  ANTIMICROBIAL ACTIVITIES OF SULFUR COMPOUNDS DERIVED FROM S-ALK (EN) YL-L-CYSTEINE SULFOXIDES IN ALLIUM AND BRASSICA , 2001 .

[142]  S. Loft,et al.  Prevention of oxidative DNA damage in rats by brussels sprouts. , 1998, Free radical research.

[143]  Mcewan,et al.  Identification of volatile organic compounds emitted in the field by oilseed rape (Brassica napus ssp. oleifera) over the growing season , 1998, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[144]  C. Gaylarde,et al.  The antimicrobial activity of an aqueous extract of Brassica negra , 1998 .

[145]  W. Peters,et al.  Effect of Brussels sprouts on oxidative DNA-damage in man. , 1997, Cancer letters.

[146]  G. W. Robertson,et al.  The identification of potential aeroallergen/irritant(s) from oilseed rape (Brassica napus spp. oleifera): volatile organic compounds emitted during flowering progression , 1994, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[147]  ED'TESoBLO,et al.  Food "Preservatives." , 1899, The Hospital.