Repellent activities of essential oils and monoterpenes against Culex pipiens pallens.

Essential oils of Eulcalyptus globulus, Lavender officinalis, Rosemarinus officinalis, and Thymus vulgaris were examined for their repellent activities against Culex pipiens pallens. All 4 essential oils effectively repelled adult mosquitoes on hairless mice. Essential oil of T. vulgaris (thyme) had potent repellent activity within the tested materials, with a protection rate of 91% at a concentration of 0.05% topical treatment. Thyme essential oil significantly extended the duration of protection until 3 bites by mosquitoes. With gas chromatography-mass spectrometry analysis, thyme essential oil was a rich source of 5 monoterpenes, including in descending order thymol, p-cymene, carvacrol, linalool, and alpha-terpinene. These 5 monoterpenes also were assessed to determine their repellent activities to the mosquitoes. alpha-Terpinene had a potent repellent activity with a protection rate of 97% at a concentration of 0.05% topical treatment. Additionally, carvacrol and thymol showed an equivalent level of repellency. A spray-type solution containing 2% alpha-terpinene was tested for its repellent activity against Cx. pipiens. This solution showed stronger repellent activity than the currently used repellent N,N-diethyl-m-methylbenzamide (deet).

[1]  Park,et al.  Cross-resistance of a chlorpyrifos-methyl resistant strain of Oryzaephilus surinamensis (Coleoptera: Cucujidae) to fumigant toxicity of essential oil extracted from Eucalyptus globulus and its major monoterpene, 1,8-cineole. , 2000, Journal of stored products research.

[2]  D. Barnard.  Repellency of essential oils to mosquitoes (Diptera: Culicidae). , 1999, Journal of medical entomology.

[3]  F. Chandre,et al.  Pyrethroid resistance in Culex quinquefasciatus from West Africa , 1998, Medical and veterinary entomology.

[4]  J. Hemingway,et al.  Resistance management strategies in malaria vector mosquito control. Baseline data for a large‐scale field trial against Anopheles albimanus in Mexico , 1998, Medical and veterinary entomology.

[5]  A. Tucker,et al.  Essential oil analysis and field evaluation of the citrosa plant "Pelargonium citrosum" as a repellent against populations of Aedes mosquitoes. , 1996, Journal of the American Mosquito Control Association.

[6]  H. Nishimura,et al.  Rotundial, a new natural mosquito repellent from the leaves of Vitex rotundifolia. , 1995, Bioscience, biotechnology, and biochemistry.

[7]  R. Gupta,et al.  Evaluation of the laboratory rabbit model for screening topical mosquito repellents. , 1994, Journal of the American Mosquito Control Association.

[8]  S. Frances,et al.  Response of Anopheles dirus and Aedes albopictus to repellents in the laboratory. , 1993, Journal of the American Mosquito Control Association.

[9]  H. Nishimura,et al.  New mosquito repellent from Eucalyptus camaldulensis , 1993 .

[10]  Marsha A. Raebel,et al.  Insect Repellent (N,N-Diethyl-m-Toluamide) Cardiovascular Toxicity in an Adult , 1993, The Annals of pharmacotherapy.

[11]  M. Perich,et al.  Botanical derivatives in mosquito control: a review. , 1991, Journal of the American Mosquito Control Association.

[12]  M. A. Ansari,et al.  Relative efficacy of various oils in repelling mosquitoes. , 1995, Indian journal of malariology.

[13]  R. Wirtz,et al.  Evaluation of the laboratory mouse model for screening topical mosquito repellents. , 1994, Journal of the American Mosquito Control Association.

[14]  F. Benoit,et al.  Dermal absorption of the insect repellent DEET (N,N-diethyl-m-toluamide) in rats and monkeys: effect of anatomical site and multiple exposure. , 1989, Journal of toxicology and environmental health.