Drug Metabolism in the Neonate and Young Infant

[1]  G. Kearns,et al.  Pharmacogenetics and development: are infants and children at increased risk for adverse outcomes? , 1995, Current opinion in pediatrics.

[2]  D. May.  Genetic Differences in Drug Disposition , 1994, Journal of clinical pharmacology.

[3]  P. Watkins.  Noninvasive tests of CYP3A enzymes. , 1994, Pharmacogenetics.

[4]  R. Isbrucker,et al.  Acetylator phenotyping: the urinary caffeine metabolite ratio in slow acetylators correlates with a marker of systemic NAT1 activity. , 1994, Pharmacogenetics.

[5]  B. Tang,et al.  Caffeine as a probe for CYP1A2 activity: potential influence of renal factors on urinary phenotypic trait measurements. , 1994, Pharmacogenetics.

[6]  D. Grant,et al.  Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions. , 1994, Pharmacogenetics.

[7]  L. Swenson,et al.  Developmental expression of human microsomal epoxide hydrolase. , 1994, The Journal of pharmacology and experimental therapeutics.

[8]  K. Mcculloch,et al.  Alterations in theophylline metabolism during the first year of life , 1993, Clinical pharmacology and therapeutics.

[9]  B. Tang,et al.  The use of caffeine for enzyme assays: A critical appraisal , 1993, Clinical pharmacology and therapeutics.

[10]  D. Grant.  Molecular genetics of the N-acetyltransferases. , 1993, Pharmacogenetics.

[11]  M. Pirmohamed,et al.  Idiosyncratic drug reactions: a mechanistic evaluation of risk factors. , 1992, British journal of clinical pharmacology.

[12]  R. Kauffman,et al.  Pharmacokinetic Studies in Paediatric Patients , 1992, Clinical pharmacokinetics.

[13]  T. Cresteil,et al.  Expression of CYP2D6 in developing human liver. , 1991, European journal of biochemistry.

[14]  M. Relling,et al.  Concordance of P450 2D6 (debrisoquine hydroxylase) phenotype and genotype: inability of dextromethorphan metabolic ratio to discriminate reliably heterozygous and homozygous extensive metabolizers. , 1991, Pharmacogenetics.

[15]  A. Rane,et al.  Differential foetal development of the O- and N-demethylation of codeine and dextromethorphan in man. , 1991, British journal of clinical pharmacology.

[16]  G. Amidon,et al.  Pharmacokinetics and Pharmacodynamics of Nifedipine in Children with Bronchopulmonary Dysplasia and Pulmonary Hypertension , 1991, Pediatric Research.

[17]  R. Finnell,et al.  Prenatal Prediction of Risk of the Fetal Hydantoin Syndrome , 1990 .

[18]  P. J. Bladeren.  Conjugation reactions in drug metabolism: An integrated approach: edited by Gerard J. Mulder, Taylor & Francis, 1990. £49.00 (413 pages) ISBN 0 85066 738 0 , 1990 .

[19]  M. Richard,et al.  Caffeine Acetylator Phenotyping during Maturation in Infants , 1990, Pediatric Research.

[20]  R. Finnell,et al.  Prenatal prediction of risk of the fetal hydantoin syndrome. , 1990, The New England journal of medicine.

[21]  D. Yealy,et al.  Survival of a child despite unusually high blood ethanol levels. , 1989, The American journal of emergency medicine.

[22]  T. Kamataki,et al.  Molecular cloning and sequence analysis of cDNA containing the entire coding region for human fetal liver cytochrome P-450. , 1989, Journal of biochemistry.

[23]  R. Isoaho,et al.  Elimination and metabolic effects of ethanol in mother, fetus, and newborn infant. , 1972, American journal of obstetrics and gynecology.

[24]  P. Pikkarainen,et al.  Development of Alcohol Dehydrogenase Activity in the Human Liver , 1967, Pediatric Research.

[25]  J. Idle,et al.  Pharmacogenetic Phenotyping and Genotyping , 1994, Clinical pharmacokinetics.

[26]  S. Wrighton,et al.  The human hepatic cytochromes P450 involved in drug metabolism. , 1992, Critical reviews in toxicology.

[27]  T. Cresteil,et al.  Cytochrome P450-dependent metabolism of dextromethorphan: fetal and adult studies. , 1992, Developmental pharmacology and therapeutics.

[28]  D. Mayers,et al.  Chloral hydrate disposition following single-dose administration to critically ill neonates and children. , 1991, Developmental pharmacology and therapeutics.

[29]  G. Pons,et al.  Developmental changes of caffeine elimination in infancy. , 1988, Developmental pharmacology and therapeutics.

[30]  A. Rane,et al.  Polymorphic acetylation of 7-amino-clonazepam in human liver cytosol. , 1984, Pediatric pharmacology.