β-Amyloid protein-dependent nitric oxide production from microglial cells and neurotoxicity

[1]  D. Ferrari,et al.  Activation of microglial cells by β-amyloid protein and interferon-γ , 1995, Nature.

[2]  D. Walker,et al.  Complement and cytokine gene expression in cultured microglia derived from postmortem human brains , 1995, Journal of neuroscience research.

[3]  L. Facci,et al.  Inflammatory Mediator Stimulation of Astrocytes and Meningeal Fibroblasts Induces Neuronal Degeneration via the Nitridergic Pathway , 1995, Journal of neurochemistry.

[4]  T. Owens,et al.  Inflammatory cytokines in the brain: does the CNS shape immune responses? , 1994, Immunology today.

[5]  P. Eikelenboom,et al.  Inflammatory mechanisms in Alzheimer's disease. , 1994, Trends in pharmacological sciences.

[6]  J. Pollock,et al.  Nitric oxide synthase activity is elevated in brain microvessels in Alzheimer's disease. , 1994, Biochemical and biophysical research communications.

[7]  Brian J Cummings,et al.  β-Amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease , 1994, Neuroscience.

[8]  T. Dawson,et al.  Gases as biological messengers: nitric oxide and carbon monoxide in the brain , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[9]  T. Owens,et al.  Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis. , 1994, International immunology.

[10]  W. McDonald,et al.  Inverse association of anti‐inflammatory treatments and Alzheimer's disease , 1994, Neurology.

[11]  Hong Wang,et al.  Induction of Nitric Oxide Synthase in Rat C6 Glioma Cells , 1994, Journal of neurochemistry.

[12]  S. Moncada,et al.  The L-arginine-nitric oxide pathway. , 1993, The New England journal of medicine.

[13]  Y. Kitamura,et al.  Inducible nitric oxide synthase in glial cells , 1993, Neuroscience Research.

[14]  L. Ignarro,et al.  Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. , 1993, Journal of immunology.

[15]  A. Nussler,et al.  Inflammation, immunoregulation, and inducible nitric oxide synthase , 1993, Journal of leukocyte biology.

[16]  D. Reis,et al.  Synthesis of nitric oxide in CNS glial cells , 1993, Trends in Neurosciences.

[17]  A. Kaszniak,et al.  Clinical trial of indomethacin in Alzheimer's disease , 1993, Neurology.

[18]  D. Dickson,et al.  Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ , 1993, Journal of Neuroimmunology.

[19]  Khadija Iqbal,et al.  Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease. , 1993, Archives of biochemistry and biophysics.

[20]  M J Ball,et al.  Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease. , 1993, The Journal of biological chemistry.

[21]  D. Dickson,et al.  Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease , 1993, Glia.

[22]  T. Molitor,et al.  Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. , 1992, Journal of immunology.

[23]  J. Marx Alzheimer's debate boils over. , 1992, Science.

[24]  C. Nathan,et al.  Nitric oxide as a secretory product of mammalian cells , 1992, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[25]  M. Simmons,et al.  Induction of Nitric Oxide Synthase in Glial Cells , 1992, Journal of neurochemistry.

[26]  G. Kreutzberg,et al.  Cytotoxicity of microglia , 1992, Journal of Neuroimmunology.

[27]  D. Selkoe,et al.  Mass spectrometry of purified amyloid beta protein in Alzheimer's disease. , 1992, The Journal of biological chemistry.

[28]  K. Boje,et al.  Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death , 1992, Brain Research.

[29]  S. Moncada The 1991 Ulf von Euler Lecture. The L-arginine: nitric oxide pathway. , 1992, Acta physiologica Scandinavica.

[30]  H. Hartung,et al.  Production of nitrite by neonatal rat microglial cells/brain macrophages. , 1992, Cellular immunology.

[31]  C. Cotman,et al.  β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease , 1992, Brain Research.

[32]  S. Moncada,et al.  Nitric oxide: physiology, pathophysiology, and pharmacology. , 1991, Pharmacological reviews.

[33]  D. Selkoe The molecular pathology of Alzheimer's disease , 1991, Neuron.

[34]  H. Eizawa,et al.  Calmodulin-independent nitric oxide synthase from rat polymorphonuclear neutrophils. , 1991, The Journal of biological chemistry.

[35]  J. Garthwaite Glutamate, nitric oxide and cell-cell signalling in the nervous system , 1991, Trends in Neurosciences.

[36]  V. Perry,et al.  Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain , 1990, Neuroscience.

[37]  D. Kirschner,et al.  Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. , 1990, Science.

[38]  P. Mcgeer,et al.  Anti-inflammatory drugs and Alzheimer disease , 1990, The Lancet.

[39]  K. Kristensson,et al.  Gamma-interferon-like immunoreactivity in axotomized rat motor neurons , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[40]  K. Beyreuther,et al.  A4 Protein in Alzheimer's Disease: Primary and Secondary Cellular Events in Extracellular Amyloid Deposition , 1989, Journal of neuropathology and experimental neurology.

[41]  T. Olsson,et al.  Interferon‐gamma‐like immunoreactivity in certain neurons of the central and peripheral nervous system , 1989, Journal of neuroscience research.

[42]  R. Henneberry,et al.  Excitatory amino acid neurotoxicity at the N-methyl-d-aspartate receptor in cultured neurons: role of the voltage-dependent magnesium block , 1989, Brain Research.

[43]  D. Selkoe,et al.  Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease , 1989, Journal of Neuroimmunology.

[44]  L. Villa-komaroff,et al.  Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. , 1989, Science.

[45]  C. Nathan,et al.  Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. , 1988, Journal of immunology.

[46]  P. Mcgeer,et al.  Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue , 1988, Neuroscience Letters.

[47]  G. Glenner Alzheimer's disease: Its proteins and genes , 1988, Cell.

[48]  M. Marletta,et al.  Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines, or interferon-gamma. , 1987, Journal of immunology.

[49]  H. Hatanaka,et al.  Differential effects of nerve-growth factor and glioma-conditioned medium on neurons cultured from various regions of fetal rat central nervous system , 1986 .

[50]  D Giulian,et al.  Characterization of ameboid microglia isolated from developing mammalian brain , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[51]  K. McCarthy,et al.  Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue , 1980, The Journal of cell biology.

[52]  J. Drapier,et al.  Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. , 1988, European journal of immunology.