An Integrated Micro-Analytical System for Complex Vapor Mixtures

A micro gas chromatograph (muGC) capable of quantitatively analyzing the components of complex vapor mixtures at trace concentrations is described. The muGC features a micro- preconcentrator/focuser (muPCF), dual-column pressure- and temperature-programmed separation module, and an integrated array of nanoparticle-coated chemiresistors. The latest design modifications and performance data are presented. Highlights include a 4-min separation of a 30-component mixture with a 3-m DRIE Si/glass microcolumn, a 14-sec separation of an 11-component mixture on a 25-cm microcolumn, a complete multi-vapor analysis from a hybrid microsystem that combines analytical, rf- wireless, and microcontroller modules, and a rapid analysis driven by a 4-stage peristaltic micropump.

[1]  A. Matzger,et al.  Chemiresistor array with nanocluster interfaces as a micro-GC detector , 2003, TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664).

[2]  K. Wise,et al.  High-performance temperature-programmed microfabricated gas chromatography columns , 2005, Journal of Microelectromechanical Systems.

[3]  R. Sacks,et al.  Stop-flow programmable selectivity with a dual-column ensemble of microfabricated etched silicon columns and air as carrier gas. , 2005, Analytical chemistry.

[4]  K. Najafi,et al.  A fully integrated high-efficiency peristaltic 18-stage gas micropump with active microvalves , 2007, 2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS).

[5]  M. Christophersen,et al.  Formation technique for macroporous morphology superlattice , 2005 .

[6]  E. Zellers,et al.  Exploiting charge-transfer complexation for selective measurement of gas-phase olefins with nanoparticle-coated chemiresistors. , 2007, Analytical chemistry.

[7]  K. Wise,et al.  First-generation hybrid MEMS gas chromatograph. , 2005, Lab on a chip.

[8]  R. Sacks,et al.  Silicon microfabricated column with microfabricated differential mobility spectrometer for GC analysis of volatile organic compounds. , 2005, Analytical chemistry.

[9]  Chunrong Jia,et al.  Rapid determination of ETS markers with a prototype field-portable GC employing a microsensor array detector. , 2007, Journal of environmental monitoring : JEM.

[10]  J. M. Bauer,et al.  Recent advancements in the gas-phase MicroChemLab , 2006, IEEE Sensors Journal.

[11]  E. Zellers,et al.  Model of vapor-induced resistivity changes in gold-thiolate monolayer-protected nanoparticle sensor films. , 2007, Analytical chemistry.

[12]  S. Terry,et al.  A gas chromatographic air analyzer fabricated on a silicon wafer , 1979, IEEE Transactions on Electron Devices.

[13]  Masoud Agah,et al.  Temperature-programmed GC using silicon microfabricated columns with integrated heaters and temperature sensors. , 2007, Analytical chemistry.

[14]  E. Zellers,et al.  Passive calibration-vapor source for a micro gas chromatograph. , 2003 .

[15]  K. Wise,et al.  Integrated high-pressure 4-stage micropump for high-speed micro gas chromatography , 2006 .

[16]  A. Noy,et al.  Ultrafast gas chromatography on single-wall carbon nanotube stationary phases in microfabricated channels. , 2006, Analytical chemistry.

[17]  A. deMello,et al.  On-chip chromatography: the last twenty years. , 2002 .

[18]  K. Najafi,et al.  A Micropump-Driven High-Speed MEMS Gas Chromatography System , 2007, TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference.

[19]  Kensall D. Wise Wireless Integrated Microsystems (WIMS): Coming Revolution in the Gathering of Information , 2005 .