blood-brain barrier function in a protein kinase Cε-dependent manner Yoshifumi Sonobe, Hideyuki Takeuchi, Kunio Kataoka, Hua Li, Shijie Jin, Maya Mimuro, Yoshio Hashizume, Yasuteru Sano, Takashi Kanda, Tetsuya Mizuno, and Akio Suzumura From the 1 Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan, the 2 Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 21 Karimata, Yazako, Nagakute-cho, Aichi 480-1195, Japan, and the 3 Department of Neurology and Clinical Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-kogushi, Ube, 755-8505, Japan.